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Eldo T Verghese

Education

Ph.D., University of Leeds, 2014

Current position

NIHR Academic Clinical Lecturer, University of Leeds (2014-current)

Publications

  1. Kapp, J. R., Diss, T., Spicer, J., Gandy, M., Schrijver, I., Jennings, L. J., Li, M. M., Tsongalis, G. J., de Castro, D. G. and Bridge, J. A. (2014). Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial. J Clin Pathol: Jclinpath-2014-202644.
  2. Verma, R., Sundara Rajan, S., Verghese, E. T., Horgan, K., Hanby, A. M. and Lane, S. (2014). Pathological evaluation of the staging axillary lymph nodes for breast cancer: a national survey in the United Kingdom. Histopathology 65(5): 707-711.
  3. Tiernan, J. P.*, Verghese, E. T.*, Nair, A., Pathak, S., Kim, B., White, J., Thygesen, H., Horgan, K. and Hanby, A. M. (2014). Systematic review and meta-analysis of cytokeratin 19-based one-step nucleic acid amplification versus histopathology for sentinel lymph node assessment in breast cancer. Br J Surg 101(4): 298-306.
  4. Dowsett, T., Verghese, E., Pollock, S., Pollard, J., Heads, J., Hanby, A. and Speirs, V. (2014). The value of archival tissue blocks in understanding breast cancer biology. J Clin Pathol 67(3): 272-275.
  5. Langlands, F. E., Dodwell, D., Hanby, A. M., Horgan, K., Millican-Slater, R. A., Speirs, V., Verghese, E. T., Smith, L. and Hughes, T. A. (2014). PSMD9 expression predicts radiotherapy response in breast cancer. Mol Cancer 13: 73.
  6. Kim, B., Verghese, E. T. and Horgan, K. (2013). Causes of false-negative sentinel node biopsy in patients with breast cancer (Br J Surg 2013; 100: 775-783). Br J Surg 100(10): 1398-1399.
  7. Soumian, S.*, Verghese, E. T.*, Booth, M., Sharma, N., Chaudhri, S., Bradley, S., Umranikar, S., Millican-Slater, R. A., Hanby, A. M. and Francis, A. (2013). Concordance between vacuum assisted biopsy and postoperative histology: implications for the proposed Low Risk DCIS Trial (LORIS). Eur J Surg Oncol 39(12): 1337-1340.
  8. Touqan, N., Diggle, C. P., Verghese, E. T., Perry, S., Horgan, K., Merchant, W., Anwar, R., Markham, A. F., Carr, I. M. and Achuthan, R. (2013). An observational study on the expression levels of MDM2 and MDMX proteins, and associated effects on P53 in a series of human liposarcomas. BMC Clin Pathol 13(1): 32.
  9. Verghese, E. T., Drury, R., Green, C. A., Holliday, D. L., Lu, X., Nash, C., Speirs, V., Thorne, J. L., Thygesen, H. H., Zougman, A., Hull, M. A., Hanby, A. M. and Hughes, T. A. (2013). MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion. J Pathol 231(3): 388-399.
  10. Kim, B., Fatayer, H., Hanby, A. M., Horgan, K., Perry, S. L., Valleley, E. M., Verghese, E. T., Williams, B. J., Thorne, J. L. and Hughes, T. A. (2013). Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer. PLoS One 8(5): e62766.
  11. Tiernan, J. P., Perry, S. L., Verghese, E. T., West, N. P., Yeluri, S., Jayne, D. G. and Hughes, T. A. (2013). Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting. Br J Cancer 108(3): 662-667.
  12. Zougman, A., Hutchins, G. G., Cairns, D. A., Verghese, E., Perry, S. L., Jayne, D. G., Selby, P. J. and Banks, R. E. (2013). Retinoic acid-induced protein 3: identification and characterisation of a novel prognostic colon cancer biomarker. Eur J Cancer 49(2): 531-539.
  13. Drury, R., Verghese, E. T. and Hughes, T. A. (2012). The roles of microRNAs in sarcomas. J Pathol 227(4): 385-391.
  14. Shaaban, A. M., Ball, G. R., Brannan, R. A., Cserni, G., Di Benedetto, A., Dent, J., Fulford, L., Honarpisheh, H., Jordan, L. and Jones, J. L. (2012). A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences. Breast Cancer Res Tr 133(3): 949-958.
  15. Verghese, E. T.*, Shenoy, H.*, Cookson, V. J., Green, C. A., Howarth, J., Partanen, R. H., Pollock, S., Waterworth, A., Speirs, V., Hughes, T. A. and Hanby, A. M. (2011). Epithelial-mesenchymal interactions in breast cancer: evidence for a role of nuclear localized beta-catenin in carcinoma-associated fibroblasts. Histopathology 59(4): 609-618.
  16. Smith, L., Brannan, R. A., Hanby, A. M., Shaaban, A. M., Verghese, E. T., Peter, M. B., Pollock, S., Satheesha, S., Szynkiewicz, M., Speirs, V. and Hughes, T. A. (2010). Differential regulation of oestrogen receptor beta isoforms by 5' untranslated regions in cancer. J Cell Mol Med 14(8): 2172-2184.
  17. Sonwalkar, S. A., Rotimi, O., Scott, N., Verghese, E., Dixon, M., Axon, A. T. and Everett, S. M. (2010). A study of indefinite for dysplasia in Barrett’s oesophagus: reproducibility of diagnosis, clinical outcomes and predicting progression with AMACR (α‐methylacyl‐CoA‐racemase). Histopathology 56(7): 900-907.
  18. Coleman, L. J., Peter, M. B., Teall, T. J., Brannan, R. A., Hanby, A. M., Honarpisheh, H., Shaaban, A. M., Smith, L., Speirs, V., Verghese, E. T., McElwaine, J. N. and Hughes, T. A. (2009). Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity. Br J Cancer 100(9): 1393-1399.
  19. Verghese, E. T., Hanby, A. M., Speirs, V. and Hughes, T. A. (2008). Small is beautiful: microRNAs and breast cancer-where are we now? J Pathol 215(3): 214-221.
  20. Verghese, E. T., den Bakker, M. A., Campbell, A., Hussein, A., Nicholson, A. G., Rice, A., Corrin, B., Rassl, D., Langman, G., Monaghan, H., Gosney, J., Seet, J., Kerr, K., Suvarna, S. K., Burke, M., Bishop, P., Pomplun, S., Willemsen, S. and Addis, B. (2008). Interobserver variation in the classification of thymic tumours--a multicentre study using the WHO classification system. Histopathology 53(2): 218-223.
  21. Verghese, E. T., Amer, K. M. and Addis, B. J. (2007). Pyothorax-associated lymphoma: an unusual variant of an unusual tumour. Histopathology 51(1): 131-133.
    *Joint first authors
Protocols by Eldo T Verghese
  1. Three Dimensional Spheroid Co-culture Invasion Assay