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Germano Cecere


Ph.D. in Human Biology and Genetics, Department of Cellular Biotechnology and Hematology (BCE), University of Rome “La Sapienza”, 2008

Current position

Associate Research Scientist, Department of Biochemistry and Molecular Biophysics, Columbia University (12/2011- to date)


  1. Cecere, G., Hoersch, S., O'Keeffe, S., Sachidanandam, R. and Grishok, A. (2014). Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape. Nat Struct Mol Biol 21(4): 358-365. [Comment in Baumann, K. (2014). Gene expression: RNAi as a global transcriptional activator. Nat Rev Mol Cell Biol 15(5): 298.]
  2. Cecere, G. and Grishok, A. (2014). A nuclear perspective on RNAi pathways in metazoans. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839(3): 223-233.
  3. Cecere, G., Hoersch, S., Jensen, M. B., Dixit, S. and Grishok, A. (2013). The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription. Mol Cell 50(6): 894-907.
  4. Avgousti, D. C., Cecere, G. and Grishok, A. (2013). The conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in Caenorhabditis elegans. Mol Cell Biol 33(5): 999-1015.
  5. Cecere, G., Zheng, G. X., Mansisidor, A. R., Klymko, K. E. and Grishok, A. (2012). Promoters recognized by forkhead proteins exist for individual 21U-RNAs. Mol Cell 47(5): 734-745. (F1000 prime recommendation)
  6. Mansisidor, A. R.*, Cecere, G.*, Hoersch, S., Jensen, M. B., Kawli, T., Kennedy, L. M., Chavez, V., Tan, M. W., Lieb, J. D. and Grishok, A. (2011). A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegans. PLoS Genet 7(9): e1002299. (*Co-first authors)
  7. Cecere, G.* and Cogoni, C.* (2009). Quelling targets the rDNA locus and functions in rDNA copy number control. BMC Microbiol 9(1): 44. (Highly accessed articles; *Co-corresponding authors)
  8. Nolan, T.*, Cecere, G.*, Mancone, C., Alonzi, T., Tripodi, M., Catalanotto, C. and Cogoni, C. (2008). The RNA-dependent RNA polymerase essential for post-transcriptional gene silencing in Neurospora crassa interacts with replication protein A. Nucleic Acids Res 36(2): 532-538. (F1000 selection; *Co-first authors)
Protocols by Germano Cecere
  1. RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans