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Corinne  Augé-Gouillou

Corinne Augé-Gouillou


Ph.D. in Endocrinology, Institut Pasteur de Paris, France, 1993

Current position

Professor in Molecular Genetics, UFR Sciences & Techniques, University François Rabelais of Tours, France
Group leader (Transposases and Genetic Instability), UFR Pharmacie, University François Rabelais of Tours, France

Publications (since 2000)

  1. Bouchet, N., Jaillet, J., Gabant, G., Brillet, B., Briseno-Roa, L., Cadene, M. and Auge-Gouillou, C. (2014). cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Res 42(2): 1117-1128.
  2. Pflieger, A., Jaillet, J., Petit, A., Auge-Gouillou, C. and Renault, S. (2014). Target capture during Mos1 transposition. J Biol Chem 289(1): 100-111.
  3. Pflieger, A., Waffo Teguo, P., Papastamoulis, Y., Chaignepain, S., Subra, F., Munir, S., Delelis, O., Lesbats, P., Calmels, C., Andreola, M. L., Merillon, J. M., Auge-Gouillou, C. and Parissi, V. (2013). Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities. PLoS One 8(11): e81184.
  4. Augé-Gouillou, C. (2013). Transposons. In: Maloy and Hughes (eds). Encyclopedia of Genetics, 2nd edition. Elsevier.
  5. Jaillet, J., Genty, M., Cambefort, J., Rouault, J. D. and Auge-Gouillou, C. (2012). Regulation of mariner transposition: the peculiar case of Mos1. PLoS One 7(8): e43365.
  6. Carpentier, G., Jaillet, J., Pflieger, A., Adet, J., Renault, S. and Auge-Gouillou, C. (2011). Transposase-transposase interactions in MOS1 complexes: a biochemical approach. J Mol Biol 405(4): 892-908.
  7. Renault, S., Demattei, M. V., Lahouassa, H., Bigot, Y. and Auge-Gouillou, C. (2010). In vitro recombination and inverted terminal repeat binding activities of the Mcmar1 transposase. Biochemistry 49(17): 3534-3544.
  8. Demattei, M. V., Thomas, X., Carnus, E., Auge-Gouillou, C. and Renault, S. (2010). Site-directed integration of transgenes: transposons revisited using DNA-binding-domain technologies. Genetica 138(5): 531-540.
  9. Bouchet, N., Bischerour, J., Germon, S., Guillard, J., Dubernet, M., Viaud-Massuard, M. C., Delelis, O., Ryabinin, V., Bigot, Y. and Auge-Gouillou, C. (2009). First Mariner Mos1 transposase inhibitors. Mini Rev Med Chem 9(4): 431-439.
  10. Casteret, S., Chbab, N., Cambefort, J., Auge-Gouillou, C., Bigot, Y. and Rouleux-Bonnin, F. (2009). Physical properties of DNA components affecting the transposition efficiency of the mariner Mos1 element. Mol Genet Genomics 282(5): 531-546.
  11. S Germon, G Carpentier, N Bouchet and C Augé-Gouilllou. (2009) Engineering the activity of Mos1 transposase. Genetica. 137: 265-276.
  12. Bigot, Y., Samain, S., Auge-Gouillou, C. and Federici, B. A. (2008). Molecular evidence for the evolution of ichnoviruses from ascoviruses by symbiogenesis. BMC Evol Biol 8: 253.
  13. Sinzelle, L., Jegot, G., Brillet, B., Rouleux-Bonnin, F., Bigot, Y. and Auge-Gouillou, C. (2008). Factors acting on Mos1 transposition efficiency. BMC Mol Biol 9: 106.
  14. Brillet, B., Bigot, Y. and Auge-Gouillou, C. (2007). Assembly of the Tc1 and mariner transposition initiation complexes depends on the origins of their transposase DNA binding domains. Genetica 130(2): 105-120.
  15. Auge-Gouillou, C., Brillet, B., Hamelin, M. H. and Bigot, Y. (2005). Assembly of the mariner Mos1 synaptic complex. Mol Cell Biol 25(7): 2861-2870.
  16. Auge-Gouillou, C., Brillet, B., Germon, S., Hamelin, M. H. and Bigot, Y. (2005). Mariner Mos1 transposase dimerizes prior to ITR binding. J Mol Biol 351(1): 117-130.
  17. Bigot, Y., Brillet, B. and Auge-Gouillou, C. (2005). Conservation of Palindromic and Mirror Motifs within Inverted Terminal Repeats of mariner-like Elements. J Mol Biol 351(1): 108-116.
  18. Leroy, H., Castagnone-Sereno, P., Renault, S., Auge-Gouillou, C., Bigot, Y. and Abad, P. (2003). Characterization of Mcmar1, a mariner-like element with large inverted terminal repeats (ITRs) from the phytoparasitic nematode Meloidogyne chitwoodi. Gene 304: 35-41.
  19. Auge-Gouillou, C., Hamelin, M. H., Demattei, M. V., Periquet, G. and Bigot, Y. (2001). The ITR binding domain of the Mariner Mos-1 transposase. Mol Genet Genomics 265(1): 58-65.
  20. Auge-Gouillou, C., Hamelin, M. H., Demattei, M. V., Periquet, M. and Bigot, Y. (2001). The wild-type conformation of the Mos-1 inverted terminal repeats is suboptimal for transposition in bacteria. Mol Genet Genomics 265(1): 51-57.
  21. Leroy, H., Leroy, F., Auge-Gouillou, C., Castagnone-Sereno, P., Vanlerberghe-Masutti, F., Bigot, Y. and Abad, P. (2000). Identification of mariner-like elements from the root-knot nematode Meloidogyne spp. Mol Biochem Parasitol 107(2): 181-190.
  22. Augé-Gouillou, C., Notareschi-Leroy, H., Abad, P., Periquet, G. and Bigot, Y. (2000). Phylogenetic analysis of the functional domains of mariner-like element (MLE) transposases. Molecular and General Genetics MGG 264(4): 506-513.
  23. Demattei, M. V., Auge-Gouillou, C., Pollet, N., Hamelin, M. H., Meunier-Rotival, M. and Bigot, Y. (2000). Features of the mammal mar1 transposons in the human, sheep, cow, and mouse genomes and implications for their evolution. Mamm Genome 11(12): 1111-1116.
Protocols by Corinne Augé-Gouillou
  1. Expression and Purification of the Eukaryotic MBP-MOS1 Transposase from Sf21 Insect Cells