Welcome guest, Login | Register


Chen Zhao


Ph.D. in Genetics, State University of New York at Stony Brook, Stony Brook, New York, 2007

Current position

Susan G. Komen Postdoctoral Fellow, Howard Hughes Medical Institute, Institute for Stem Cell and Regenerative Medicine Stanford University (Laboratory of Dr. Philip A. Beachy) (2011-present)


  1. Zhao, C. (2014). Paracrine signaling in stem cell renewal and in neoplastic tumor growth. Sci China Life Sci 57(6): 571-574.
  2. Ford, B., Boykevisch, S., Zhao, C., Kunzelmann, S., Bar-Sagi, D., Herrmann, C. and Nassar, N. (2009). Characterization of a Ras mutant with identical GDP- and GTP-bound structures. Biochemistry 48(48): 11449-11457.
  3. Garcia, A., Zheng, Y., Zhao, C., Toschi, A., Fan, J., Shraibman, N., Brown, H. A., Bar-Sagi, D., Foster, D. A. and Arbiser, J. L. (2008). Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells. Clin Cancer Res 14(13): 4267-42744.
  4. Zhao, C., Du, G., Skowronek, K., Frohman, M. A. and Bar-Sagi, D. (2007). Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol 9(6): 706-712.
  5. Tartaglia, M., Pennacchio, L. A., Zhao, C., Yadav, K. K., Fodale, V., Sarkozy, A., Pandit, B., Oishi, K., Martinelli, S., Schackwitz, W., Ustaszewska, A., Martin, J., Bristow, J., Carta, C., Lepri, F., Neri, C., Vasta, I., Gibson, K., Curry, C. J., Siguero, J. P., Digilio, M. C., Zampino, G., Dallapiccola, B., Bar-Sagi, D. and Gelb, B. D. (2007). Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome. Nat Genet 39(1): 75-79.
  6. Boykevisch, S., Zhao, C., Sondermann, H., Philippidou, P., Halegoua, S., Kuriyan, J. and Bar-Sagi, D. (2006). Regulation of ras signaling dynamics by Sos-mediated positive feedback. Curr Biol 16(21): 2173-2179.
  7. Sondermann, H.*, Zhao, C.* and Bar-Sagi, D. (2005). Analysis of Ras:RasGEF interactions by phage display and static multi-angle light scattering. Methods 37(2): 197-202. (*Equal contribution)
  8. Shi, Q., Zhangn, Y., Zhao, C., Zhong, Y., Huang, D. and Ma, D. (2000). The expression and purificiation of human Annexin V overexpressed in E. coli and the detection of apoptosis. Journal of Beijing Medical University 33(2): 167-169.
Protocols by Chen Zhao
  1. Wnt Reporter Activity Assay
  2. Hedgehog (Hh) Reporter Activity Assay