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Hailong Zhang

Education

Ph.D. in Tumor Immunology, Tongji medical college, Huazhong University of Science and Technology, Wuhan, China, 2007

Current position

Research Associate, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, U.S.A

Publications

  1. Zhang, H., He, J., Li, J., Tian, D., Gu, L. and Zhou, M. (2013). Methylation of RASSF1A gene promoter is regulated by p53 and DAXX. FASEB J 27(1): 232-242.
  2. Gu, L.*, Zhang, H.*, He, J., Li, J., Huang, M. and Zhou, M. (2012). MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells. Oncogene 31(11): 1342-1353. (*Co-First Author)
  3. Zhou, S., Gu, L., He, J., Zhang, H. and Zhou, M. (2011). MDM2 regulates vascular endothelial growth factor mRNA stabilization in hypoxia. Mol Cell Biol 31(24): 4928-4937.
  4. He, J., Gu, L., Zhang, H. and Zhou, M. (2011). Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma. Cell Cycle 10(17): 2994-3002.
  5. Chen, H., Xiao, L., Zhang, H., Liu, N., Liu, T., Liu, L., Hu, X., Yan, D., Yang, K., Yin, B., Wang, J., Li, Q. and Li, Z. (2011). The involvement of beta-actin in the signaling of transmembrane TNF-alpha-mediated cytotoxicity. J Leukoc Biol 89(6): 917-926.
  6. Chen, Y., Wang, X., Li, W., Zhang, H., Zhao, C., Li, Y., Wang, Z. and Chen, C. (2011). Sp1 upregulates survivin expression in adenocarcinoma of lung cell line A549. Anat Rec (Hoboken) 294(5): 774-780.
  7. Zhang, H., Yan, D., Shi, X., Liang, H., Pang, Y., Qin, N., Chen, H., Wang, J., Yin, B., Jiang, X., Feng, W., Zhang, W., Zhou, M. and Li, Z. (2008). Transmembrane TNF-alpha mediates "forward" and "reverse" signaling, inducing cell death or survival via the NF-kappaB pathway in Raji Burkitt lymphoma cells. J Leukoc Biol 84(3): 789-797.
  8. He, J., Gu, L., Zhang, H. and Zhou, M. (2011). Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma. Cell Cycle 10(17): 2994-3002.
  9. Chen, H., Xiao, L., Zhang, H., Liu, N., Liu, T., Liu, L., Hu, X., Yan, D., Yang, K., Yin, B., Wang, J., Li, Q. and Li, Z. (2011). The involvement of beta-actin in the signaling of transmembrane TNF-alpha-mediated cytotoxicity. J Leukoc Biol 89(6): 917-926.
  10. Chen, Y., Wang, X., Li, W., Zhang, H., Zhao, C., Li, Y., Wang, Z. and Chen, C. (2011). Sp1 upregulates survivin expression in adenocarcinoma of lung cell line A549. Anat Rec (Hoboken) 294(5): 774-780.
  11. Gu, L., Zhang, H., He, J., Li, J., Huang, M. and Zhou, M. (2012). MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells. Oncogene 31(11): 1342-1353.
  12. Zhang, S., Liu, T., Liang, H., Zhang, H., Yan, D., Wang, N., Jiang, X., Feng, W., Wang, J., Li, P. and Li, Z. (2009). Lipid rafts uncouple surface expression of transmembrane TNF-alpha from its cytotoxicity associated with ICAM-1 clustering in Raji cells. Mol Immunol 46(7): 1551-1560.
  13. Yan, D., Qin, N., Zhang, H., Liu, T., Yu, M., Jiang, X., Feng, W., Wang, J., Yin, B., Zhang, T., Zhou, M. and Li, Z. (2009). Expression of TNF-alpha leader sequence renders MCF-7 tumor cells resistant to the cytotoxicity of soluble TNF-alpha. Breast Cancer Res Treat 116(1): 91-102.
  14. Zhang, H., Yan, D., Shi, X., Liang, H., Pang, Y., Qin, N., Chen, H., Wang, J., Yin, B., Jiang, X., Feng, W., Zhang, W., Zhou, M. and Li, Z. (2008). Transmembrane TNF-alpha mediates "forward" and "reverse" signaling, inducing cell death or survival via the NF-kappaB pathway in Raji Burkitt lymphoma cells. J Leukoc Biol 84(3): 789-797.
  15. Liang, H., Yin, B., Zhang, H., Zhang, S., Zeng, Q., Wang, J., Jiang, X., Yuan, L., Wang, C. Y. and Li, Z. (2008). Blockade of tumor necrosis factor (TNF) receptor type 1-mediated TNF-alpha signaling protected Wistar rats from diet-induced obesity and insulin resistance. Endocrinology 149(6): 2943-2951.
  16. Chen, H., Zhang, H., Qin, N., Jiang, X. and Li, Z. (2007). Study of the function of actin in TM-TNFα induced cell apoptosis by TNFRII. (30200257) Journal of Huazhong Medicine 31(3): 195-197.
  17. Xin, L., Wang, J., Zhang, H., Shi, W., Yu, M., Li, Q., Jiang, X., Gong, F., Gardner, K., Li, Q. Q. and Li, Z. (2006). Dual regulation of soluble tumor necrosis factor-alpha induced activation of human monocytic cells via modulating transmembrane TNF-alpha-mediated 'reverse signaling'. Int J Mol Med 18(5): 885-892.
  18. Fan, W., Zhang, H. L. and Wu, X. M. (2005). [Enhancement effect of nucleotide excision repair gene xeroderma pigmentosun group a antisense RNA on sensitivity of human lung adenocarcinoma cell line A549 to cisplatin]. Ai Zheng 24(4): 403-407.
Protocols by Hailong Zhang
  1. Polysome Preparation, RNA Isolation and Analysis
  2. In vitro RNA-protein Binding Assay by UV Crosslinking