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Xiumin Yan


Ph.D. in Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 2002

Current position

Associate Professor, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China


  1. Zhao, H., Zhu, L., Zhu, Y., Cao, J., Li, S., Huang, Q., Xu, T., Huang, X., Yan, X.* and Zhu, X.* (2013). The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis. Nat Cell Biol 15(12): 1434-1444. (*Co-corresponding author)
  2. Ran, X., Bian, X., Ji, Y., Yan, X., Yang, F. and Li, F. (2013). White spot syndrome virus IE1 and WSV056 modulate the G1/S transition by binding to the host retinoblastoma protein. J Virol 87(23): 12576-12582.
  3. Yan, X. and Zhu, X. (2013). Branched F-actin as a negative regulator of cilia formation. Exp Cell Res 319(2): 147-151.
  4. Cao, J., Shen, Y., Zhu, L., Xu, Y., Zhou, Y., Wu, Z., Li, Y., Yan, X.* and Zhu, X.* (2012). miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat Cell Biol 14(7): 697-706. (*Co-corresponding author)
  5. Zhao, H., Zhu, L., Jin, Y., Ji, H., Yan, X.* and Zhu, X.* (2012). miR-375 is highly expressed and possibly transactivated by achaete-scute complex homolog 1 in small-cell lung cancer cells. Acta Biochim Biophys Sin (Shanghai) 44(2): 177-182. (*Co-corresponding author)
  6. Ruan, L., Bian, X., Ji, Y., Li, M., Li, F. and Yan, X.* (2011). Isolation and identification of novel microRNAs from Marsupenaeus japonicus. Fish Shellfish Immunol 31(2): 334-340.
  7. Yan, X., Shen, Y. and Zhu, X. (2010). Live show of Rho GTPases in cell migration. J Mol Cell Biol 2(2): 68-69.
  8. Li, F., Li, M., Ke, W., Ji, Y., Bian, X. and Yan, X.* (2009). Identification of the immediate-early genes of white spot syndrome virus. Virology 385(1): 267-274.
  9. van Wijk, E., Kersten, F. F., Kartono, A., Mans, D. A., Brandwijk, K., Letteboer, S. J., Peters, T. A., Marker, T., Yan, X., Cremers, C. W., Cremers, F. P., Wolfrum, U., Roepman, R. and Kremer, H. (2009). Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein. Hum Mol Genet 18(1): 51-64.
  10. Ruan, L., Bian, X., Wang, X., Yan, X., Li, F. and Xu, X. (2008). Molecular characteristics of the tubeworm, Ridgeia piscesae, from the deep-sea hydrothermal vent. Extremophiles 12(5): 735-739.
  11. Mikolajka, A., Yan, X., Popowicz, G. M., Smialowski, P., Nigg, E. A. and Holak, T. A. (2006). Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. J Mol Biol 359(4): 863-875.
  12. Yan, X., Habedanck, R. and Nigg, E. A. (2006). A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Mol Biol Cell 17(2): 634-644.
  13. Liang, Y., Yu, W., Li, Y., Yang, Z., Yan, X., Huang, Q. and Zhu, X. (2004). Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J Cell Biol 164(4): 557-566.
  14. Yan, X., Li, F., Liang, Y., Shen, Y., Zhao, X., Huang, Q. and Zhu, X. (2003). Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle. Mol Cell Biol 23(4): 1239-1250.
  15. Yan, X., Zhao, X., Qian, M., Guo, N., Gong, X. and Zhu, X. (2000). Characterization and gene structure of a novel retinoblastoma-protein-associated protein similar to the transcription regulator TFII-I. Biochem J 345 Pt 3: 749-757.
Protocols by Xiumin Yan
  1. Fluorescence Microscopy for Cilia in Cultured Cells and Zebrafish Embryos