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Michael Sauer


Ph.D. in Biology, ZMBP University of Tübingen, Germany

Current position

Senior Researcher, Institute for Biochemistry and Biology, University of Potsdam, Germany


Original articles

  1. Sauer, M., Delgadillo, M. O., Zouhar, J., Reynolds, G. D., Pennington, J. G., Jiang, L., Liljegren, S. J., Stierhof, Y. D., De Jaeger, G., Otegui, M. S., Bednarek, S. Y. and Rojo, E. (2013). MTV1 and MTV4 encode plant-specific ENTH and ARF GAP proteins that mediate clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network. Plant Cell 25(6): 2217-2235.
  2. Covanova, M., Sauer, M., Rychtar, J., Friml, J., Petrasek, J. and Zazimalova, E. (2013). Overexpression of the auxin binding protein1 modulates PIN-dependent auxin transport in tobacco cells. PLoS One 8(7): e70050.
  3. Ballesteros, I., Dominguez, T., Sauer, M., Paredes, P., Duprat, A., Rojo, E., Sanmartin, M. and Sanchez-Serrano, J. J. (2013). Specialized functions of the PP2A subfamily II catalytic subunits PP2A-C3 and PP2A-C4 in the distribution of auxin fluxes and development in Arabidopsis. Plant J 73(5): 862-872.
  4. Lanza, M., Garcia-Ponce, B., Castrillo, G., Catarecha, P., Sauer, M., Rodriguez-Serrano, M., Paez-Garcia, A., Sanchez-Bermejo, E., T, C. M., Leo del Puerto, Y., Sandalio, L. M., Paz-Ares, J. and Leyva, A. (2012). Role of actin cytoskeleton in brassinosteroid signaling and in its integration with the auxin response in plants. Dev Cell 22(6): 1275-1285.
  5. Sanmartin, M., Sauer, M., Munoz, A., Zouhar, J., Ordonez, A., van de Ven, W. T., Caro, E., de la Paz Sanchez, M., Raikhel, N. V., Gutierrez, C., Sanchez-Serrano, J. J. and Rojo, E. (2011). A molecular switch for initiating cell differentiation in Arabidopsis. Curr Biol 21(12): 999-1008.
  6. Sauer, M. and Friml, J. (2010). Immunolocalization of proteins in plants. Methods Mol Biol 655: 253-263.
  7. Robert, S., Kleine-Vehn, J., Barbez, E., Sauer, M., Paciorek, T., Baster, P., Vanneste, S., Zhang, J., Simon, S., Covanova, M., Hayashi, K., Dhonukshe, P., Yang, Z., Bednarek, S. Y., Jones, A. M., Luschnig, C., Aniento, F., Zazimalova, E. and Friml, J. (2010). ABP1 mediates auxin inhibition of clathrin-dependent endocytosis in Arabidopsis. Cell 143(1): 111-121.
  8. Wabnik, K., Kleine-Vehn, J., Balla, J., Sauer, M., Naramoto, S., Reinohl, V., Merks, R. M., Govaerts, W. and Friml, J. (2010). Emergence of tissue polarization from synergy of intracellular and extracellular auxin signaling. Mol Syst Biol 6: 447.
  9. Bayer, E. M., Smith, R. S., Mandel, T., Nakayama, N., Sauer, M., Prusinkiewicz, P. and Kuhlemeier, C. (2009). Integration of transport-based models for phyllotaxis and midvein formation. Genes Dev 23(3): 373-384.
  10. Titapiwatanakun, B., Blakeslee, J. J., Bandyopadhyay, A., Yang, H., Mravec, J., Sauer, M., Cheng, Y., Adamec, J., Nagashima, A., Geisler, M., Sakai, T., Friml, J., Peer, W. A. and Murphy, A. S. (2009). ABCB19/PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis. Plant J 57(1): 27-44.
  11. Santelia, D., Henrichs, S., Vincenzetti, V., Sauer, M., Bigler, L., Klein, M., Bailly, A., Lee, Y., Friml, J., Geisler, M. and Martinoia, E. (2008). Flavonoids redirect PIN-mediated polar auxin fluxes during root gravitropic responses. J Biol Chem 283(45): 31218-31226.
  12. Dubrovsky, J. G., Sauer, M., Napsucialy-Mendivil, S., Ivanchenko, M. G., Friml, J., Shishkova, S., Celenza, J. and Benkova, E. (2008). Auxin acts as a local morphogenetic trigger to specify lateral root founder cells. Proc Natl Acad Sci U S A 105(25): 8790-8794.
  13. Kleine-Vehn, J., Dhonukshe, P., Sauer, M., Brewer, P. B., Wisniewska, J., Paciorek, T., Benkova, E. and Friml, J. (2008). ARF GEF-dependent transcytosis and polar delivery of PIN auxin carriers in Arabidopsis. Curr Biol 18(7): 526-531.
  14. Kleine-Vehn, J., Leitner, J., Zwiewka, M., Sauer, M., Abas, L., Luschnig, C. and Friml, J. (2008). Differential degradation of PIN2 auxin efflux carrier by retromer-dependent vacuolar targeting. Proc Natl Acad Sci U S A 105(46): 17812-17817.
  15. Blakeslee, J. J., Bandyopadhyay, A., Lee, O. R., Mravec, J., Titapiwatanakun, B., Sauer, M., Makam, S. N., Cheng, Y., Bouchard, R., Adamec, J., Geisler, M., Nagashima, A., Sakai, T., Martinoia, E., Friml, J., Peer, W. A. and Murphy, A. S. (2007). Interactions among PIN-FORMED and P-glycoprotein auxin transporters in Arabidopsis. Plant Cell 19(1): 131-147.
  16. Sauer, M., Balla, J., Luschnig, C., Wisniewska, J., Reinohl, V., Friml, J. and Benkova, E. (2006). Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. Genes Dev 20(20): 2902-2911.
  17. Xu, J., Hofhuis, H., Heidstra, R., Sauer, M., Friml, J. and Scheres, B. (2006). A molecular framework for plant regeneration. Science 311(5759): 385-388.
  18. Sauer, M., Paciorek, T., Benkova, E. and Friml, J. (2006). Immunocytochemical techniques for whole-mount in situ protein localization in plants. Nat Protoc 1(1): 98-103.
  19. Paciorek, T., Sauer, M., Balla, J., Wisniewska, J. and Friml, J. (2006). Immunocytochemical technique for protein localization in sections of plant tissues. Nat Protoc 1(1): 104-107.
  20. Weijers, D., Sauer, M., Meurette, O., Friml, J., Ljung, K., Sandberg, G., Hooykaas, P. and Offringa, R. (2005). Maintenance of embryonic auxin distribution for apical-basal patterning by PIN-FORMED-dependent auxin transport in Arabidopsis. Plant Cell 17(9): 2517-2526.
  21. Sauer, M. and Friml, J. (2004). In vitro culture of Arabidopsis embryos within their ovules. Plant J 40(5): 835-843.
  22. Benkova, E., Michniewicz, M., Sauer, M., Teichmann, T., Seifertova, D., Jurgens, G. and Friml, J. (2003). Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell 115(5): 591-602.
  23. Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., Offringa, R. and Jurgens, G. (2003). Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis. Nature 426(6963): 147-153.


  1. Sauer, M., Robert, S. and Kleine-Vehn, J. (2013). Auxin: simply complicated. J Exp Bot 64(9): 2565-2577.
  2. Sanmartin, M., Sauer, M., Munoz, A. and Rojo, E. (2012). MINIYO and transcriptional elongation: lifting the roadblock to differentiation. Transcription 3(1): 25-28.
  3. Sauer, M. and Kleine-Vehn, J. (2011). AUXIN BINDING PROTEIN1: the outsider. Plant Cell 23(6): 2033-2043.
  4. Vieten, A., Sauer, M., Brewer, P. B. and Friml, J. (2007). Molecular and cellular aspects of auxin-transport-mediated development. Trends Plant Sci 12(4): 160-168.
  5. Bandyopadhyay, A., Blakeslee, J. J., Lee, O. R., Mravec, J., Sauer, M., Titapiwatanakun, B., Makam, S. N., Bouchard, R., Geisler, M., Martinoia, E., Friml, J., Peer, W. A. and Murphy, A. S. (2007). Interactions of PIN and PGP auxin transport mechanisms. Biochem Soc Trans 35(Pt 1): 137-141.

Mini-reviews and bookchapters

  1. Sauer, M. and Friml, J. (2014). Plant biology: gatekeepers of the road to protein perdition. Curr Biol 24(1): R27-29.
  2. Sauer, M. and Friml, J. (2011). Fleeting hormone cues get stabilized for plant organogenesis. Mol Syst Biol 7: 507.
  3. Sauer, M. and Friml, J. (2010). Immunolocalization of proteins in plants. Methods Mol Biol 655: 253-263.
  4. Friml, J. and Sauer, M. (2008). Plant biology: in their neighbour's shadow. Nature 453(7193): 298-299.
  5. Sauer, M. and Friml, J. (2008). In vitro culture of Arabidopsis embryos. Methods Mol Biol 427: 71-76.
  6. Sauer, M. and Friml, J. (2008). Visualization of auxin gradients in embryogenesis. Methods Mol Biol 427: 137-144.
  7. Sauer, M. and Friml, J. (2004). The Matryoshka dolls of plant polarity. Development 131(23): 5774–5775.
Protocols by Michael Sauer
  1. MTV1 Pull-down Assay in Arabidopsis