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Cristina Pina


Ph.D. in Clinical Medicine, Wolfson College, University of Oxford, UK, 2008
M.D., Faculty of Medicine, University of Lisbon, Portugal, 1998

Current position

Research Associate (Independent Scientist), Department of Haematology, University of Cambridge, UK


  1. Teles, J., Enver, T., Pina, C.* (2014). Single-cell PCR profiling of gene expression in hematopoiesis. In: Bunting, K. D. (ed). Haematopoietic Stem Cell Protocols 3rd Edition. (In press) (*Corresponding author)
  2. Swiers, G., Baumann, C., O'Rourke, J., Giannoulatou, E., Taylor, S., Joshi, A., Moignard, V., Pina, C., Bee, T., Kokkaliaris, K. D., Yoshimoto, M., Yoder, M. C., Frampton, J., Schroeder, T., Enver, T., Gottgens, B. and de Bruijn, M. F. (2013). Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nat Commun 4: 2924.
  3. May, G., Soneji, S., Tipping, A. J., Teles, J., McGowan, S. J., Wu, M., Guo, Y., Fugazza, C., Brown, J., Karlsson, G., Pina, C., Olariu, V., Taylor, S., Tenen, D. G., Peterson, C. and Enver, T. (2013). Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors. Cell Stem Cell 13(6): 754-768.
  4. Teles, J., Pina, C., Eden, P., Ohlsson, M., Enver, T. and Peterson, C. (2013). Transcriptional regulation of lineage commitment--a stochastic model of cell fate decisions. PLoS Comput Biol 9(8): e1003197.
  5. Karlsson, G., Rorby, E., Pina, C., Soneji, S., Reckzeh, K., Miharada, K., Karlsson, C., Guo, Y., Fugazza, C., Gupta, R., Martens, J. H., Stunnenberg, H. G., Karlsson, S. and Enver, T. (2013). The tetraspanin CD9 affords high-purity capture of all murine hematopoietic stem cells. Cell Rep 4(4): 642-648.
  6. Pina, C., Fugazza, C., Tipping, A. J., Brown, J., Soneji, S., Teles, J., Peterson, C. and Enver, T. (2012). Inferring rules of lineage commitment in haematopoiesis. Nat Cell Biol 14(3): 287-294.
  7. De Gobbi, M., Garrick, D., Lynch, M., Vernimmen, D., Hughes, J. R., Goardon, N., Luc, S., Lower, K. M., Sloane-Stanley, J. A., Pina, C., Soneji, S., Renella, R., Enver, T., Taylor, S., Jacobsen, S. E., Vyas, P., Gibbons, R. J. and Higgs, D. R. (2011). Generation of bivalent chromatin domains during cell fate decisions. Epigenetics Chromatin 4(1): 9.
  8. Tipping, A. J., Pina, C., Castor, A., Hong, D., Rodrigues, N. P., Lazzari, L., May, G. E., Jacobsen, S. E. and Enver, T. (2009). High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. Blood 113(12): 2661-2672.
  9. Pina, C., May, G., Soneji, S., Hong, D. and Enver, T. (2008). MLLT3 regulates early human erythroid and megakaryocytic cell fate. Cell Stem Cell 2(3): 264-273.
  10. Pina, C.* and Enver, T. (2007). Differential contributions of haematopoietic stem cells to foetal and adult haematopoiesis: insights from functional analysis of transcriptional regulators. Oncogene 26(47): 6750-6765. (*Corresponding author)
  11. Pina, C., Pinto, F., Feijo, J. A. and Becker, J. D. (2005). Gene family analysis of the Arabidopsis pollen transcriptome reveals biological implications for cell growth, division control, and gene expression regulation. Plant Physiol 138(2): 744-756.
  12. Carvalho, C., Pereira, H. M., Ferreira, J., Pina, C., Mendonca, D., Rosa, A. C. and Carmo-Fonseca, M. (2001). Chromosomal G-dark bands determine the spatial organization of centromeric heterochromatin in the nucleus. Mol Biol Cell 12(11): 3563-3572.
Protocols by Cristina Pina
  1. EML Erythroid and Neutrophil Differentiation Protocols