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Mackenzie K. Herroon

Mackenzie K. Herroon


M.A. in Psychology, concentration in Behavioral Neuroscience, University of Delaware, 2008

Current position

Research Assistant, Podgorski Laboratory, Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI


  1. Respondek, T., Sharma, R., Herroon, M. K., Garner, R. N., Knoll, J. D., Cueny, E., Turro, C., Podgorski, I. and Kodanko, J. J. (2014). Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound. ChemMedChem. (Epub ahead of print)
  2. Hardaway, A. L., Herroon, M. K., Rajagurubandara, E. and Podgorski, I. (2014). Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases. Cancer Metastasis Rev. (Epub ahead of print)
  3. Herroon, M. K., Rajagurubandara, E., Hardaway, A. L., Powell, K.*, Turchick, A., Feldmann, D. and Podgorski, I. (2013). Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms. Oncotarget 4(11): 2108-2123.
  4. Herroon, M. K., Rajagurubandara, E., Rudy, D. L., Chalasani, A., Hardaway, A. L. and Podgorski, I. (2013). Macrophage cathepsin K promotes prostate tumor progression in bone. Oncogene 32(12): 1580-1593.
  5. Respondek, T., Garner, R. N., Herroon, M. K., Podgorski, I., Turro, C. and Kodanko, J. J. (2011). Light activation of a cysteine protease inhibitor: caging of a peptidomimetic nitrile with Ru(II)(bpy)2. J Am Chem Soc 133(43): 17164-17167.
  6. Podgorski, I., Linebaugh, B. E., Koblinski, J. E., Rudy, D. L., Herroon, M. K., Olive, M. B. and Sloane, B. F. (2009). Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. Am J Pathol 175(3): 1255-1269.
Protocols by Mackenzie K. Herroon
  1. Transwell Co-culture of Bone Marrow Macrophages with Tumor Cells