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Modesto Redrejo-Rodríguez


Ph.D. in Molecular Biology, Madrid Autonomous University, Spain, 2009

Current position

Postdoctoral researcher, Molecular Biology Center (CSIC), Madrid, Spain


  1. Redrejo-Rodríguez, M. and Salas, M. L. (2014). Repair of base damage and genome maintenance in the nucleo-cytoplasmic large DNA viruses. Virus Res 179: 12-25.
  2. Holguera, I., Redrejo-Rodríguez, M., Salas, M. and Muñoz-Espín, D. (2014). New insights in the varphi29 terminal protein DNA-binding and host nucleoid localization functions. Mol Microbiol 91(2): 232-241.
  3. RRedrejo-Rodríguez, M., Muñoz-Espín, D., Holguera, I., Mencía, M. and Salas, M. (2013). Nuclear and nucleoid localization are independently conserved functions in bacteriophage terminal proteins. Mol Microbiol 90(4): 858-868.
  4. Redrejo-Rodríguez, M., Rodríguez, J. M., Suárez, C., Salas, J. and Salas, M. L. (2013). Involvement of the reparative DNA polymerase Pol X of African swine fever virus in the maintenance of viral genome stability in vivo. J Virol 87(17): 9780-9787.
  5. Redrejo-Rodríguez, M., Muñoz-Espín, D., Holguera, I., Mencía, M. and Salas, M. (2012). Functional eukaryotic nuclear localization signals are widespread in terminal proteins of bacteriophages. Proc Natl Acad Sci U S A 109(45): 18482-18487.
  6. Redrejo-Rodríguez, M., Muñoz-Espín, D., Holguera, I., Mencía, M. and Salas, M. (2013). Nuclear localization signals in phage terminal proteins provide a novel gene delivery tool in mammalian cells. Commun Integr Biol 6(2): e22829.
  7. Redrejo-Rodríguez, M., Saint-Pierre, C., Couve, S., Mazouzi, A., Ishchenko, A. A., Gasparutto, D. and Saparbaev, M. (2011). New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. PLoS One 6(7): e21039.
  8. Gelin, A., Redrejo-Rodríguez, M., Laval, J., Fedorova, O. S., Saparbaev, M. and Ishchenko, A. A. (2010). Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. PLoS One 5(8): e12241.
  9. Redrejo-Rodríguez, M., Ishchenko, A. A., Saparbaev, M. K., Salas, M. L. and Salas, J. (2009). African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. Virology 390(1): 102-109.
  10. Rodríguez, I., Nogal, M. L., Redrejo-Rodríguez, M., Bustos, M. J. and Salas, M. L. (2009). The African swine fever virus virion membrane protein pE248R is required for virus infectivity and an early postentry event. J Virol 83(23): 12290-12300.
  11. Redrejo-Rodríguez, M., García-Escudero, R., Yáñez-Muñoz, R. J., Salas, M. L. and Salas, J. (2006). African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. J Virol 80(10): 4847-4857.
  12. Rodríguez, I., Redrejo-Rodríguez, M., Rodríguez, J. M., Alejo, A., Salas, J. and Salas, M. L. (2006). African swine fever virus pB119L protein is a flavin adenine dinucleotide-linked sulfhydryl oxidase. J Virol 80(7): 3157-3166.
  13. Redrejo-Rodríguez, M., Tejeda-Cano, A., del Carmen Pinto, M. and Macı́as, P. (2004). Lipoxygenase inhibition by flavonoids: semiempirical study of the structure–activity relation. Journal of Molecular Structure: THEOCHEM 674(1): 121-124.
Protocols by Modesto Redrejo-Rodríguez
  1. Determination of Mutation Frequency During Viral DNA Replication