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Fabrizio d’Adda di Fagagna

Fabrizio d’Adda di Fagagna


Ph.D. in Molecular Genetics (HIV-1 transcription), International School for Advanced Studies (ISAS-SISSA), Trieste, Italy, 1995

Current position

Tenured Principal Investigator, IFOM Foundation, Milan, Italy (2009-present)
Group leader at the Molecular Genetic Institute (IGM) of the National Research Council, Pavia, Italy (2012-present)


  1. Francia, S., Michelini, F., Saxena, A., Tang, D., de Hoon, M., Anelli, V., Mione, M., Carninci, P. and d'Adda di Fagagna, F. (2012). Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 488(7410): 231-235.
    Citations: 22
    Faculty of 1000: Highlighted as “Must read”. FFa=8
  2. Fumagalli, M., Rossiello, F., Clerici, M., Barozzi, S., Cittaro, D., Kaplunov, J. M., Bucci, G., Dobreva, M., Matti, V., Beausejour, C. M., Herbig, U., Longhese, M. P. and d'Adda di Fagagna, F. (2012). Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat Cell Biol 14(4): 355-365.
    Commented by P. Adams in the same issue and by J.J. Jacobs in NRMCB. Highlighted in Nature Reviews Molecular Cell Biology.Highlighted in Science.
    Citations: 30
  3. d'Adda di Fagagna, F. (2008). Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer 8(7): 512-522.
    Citations: 177
  4. Di Micco, R., Fumagalli, M., Cicalese, A., Piccinin, S., Gasparini, P., Luise, C., Schurra, C., Garre, M., Nuciforo, P. G., Bensimon, A., Maestro, R., Pelicci, P. G. and d'Adda di Fagagna, F. (2006). Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444(7119): 638-642.
    Citations: 666
    Faculty of 1000: Highlighted as “Must read”. FFa=9
  5. d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., Fiegler, H., Carr, P., Von Zglinicki, T., Saretzki, G., Carter, N. P. and Jackson, S. P. (2003). A DNA damage checkpoint response in telomere-initiated senescence. Nature 426(6963): 194-198.
    Citations: 1160
    Faculty of 1000: Highlighted as “Must read”. FFa=8

    Citation records are according to Google Scholar and Faculty of 1000 on March 2013

Protocols by Fabrizio d’Adda di Fagagna
  1. ImmunoFISH for Mice and Baboons Frozen Sections
  2. ImmunoFISH for Adherent Cultured Mammalian Cells