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Fabrizio   Pontarelli

Fabrizio Pontarelli


Bachelor in Biomedical Science and Technology at the University of Rome “La Sapienza” (108/110), Italy, 2003

Work experience

Research Technician, Dept. of Neuroscience, Albert Einstein College of Medicine, New York


  1. Ofengeim, D., Chen, Y. B., Miyawaki, T., Li, H., Sacchetti, S., Flannery, R. J., Alavian, K. N., Pontarelli, F., Roelofs, B. A., Hickman, J. A., Hardwick, J. M., Zukin, R. S. and Jonas, E. A. (2012). N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nat Neurosci 15(4): 574-580.
  2. Giorgi, F. S., Pizzanelli, C., Ferrucci, M., Lazzeri, G., Faetti, M., Giusiani, M., Pontarelli, F., Busceti, C. L., Murri, L. and Fornai, F. (2005). Previous exposure to (+/-) 3,4-methylenedioxymethamphetamine produces long-lasting alteration in limbic brain excitability measured by electroencephalogram spectrum analysis, brain metabolism and seizure susceptibility. Neuroscience 136(1): 43-53.
  3. Fornai, F., Schluter, O. M., Lenzi, P., Gesi, M., Ruffoli, R., Ferrucci, M., Lazzeri, G., Busceti, C. L., Pontarelli, F., Battaglia, G., Pellegrini, A., Nicoletti, F., Ruggieri, S., Paparelli, A. and Sudhof, T. C. (2005). Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proc Natl Acad Sci U S A 102(9): 3413-3418.
  4. Cappuccio, I., Calderone, A., Busceti, C. L., Biagioni, F., Pontarelli, F., Bruno, V., Storto, M., Terstappen, G. T., Gaviraghi, G., Fornai, F., Battaglia, G., Melchiorri, D., Zukin, R. S., Nicoletti, F. and Caricasole, A. (2005). Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death. J Neurosci 25(10): 2647-2657.
  5. Battaglia, G., Busceti, C. L., Pontarelli, F., Biagioni, F., Fornai, F., Paparelli, A., Bruno, V., Ruggieri, S. and Nicoletti, F. (2003). Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology 45(2): 155-166.
Protocols by Fabrizio Pontarelli
  1. Mouse Transient Global Ischemia Two-Vessel Occlusion Model