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Coauthors
John Beatty Department of Microbiology and Immunology, University of British Columbia, Canada
5 protocols

Paul Fogg Department of Microbiology and Immunology, University of British Columbia, Canada
1 protocol
Coreviewers
Esteban Paredes-Osses Institute of Public Health, Chile
5 protocols

Migla Miskinyte University of Edinburgh
6 protocols

Sofiane El-Kirat-Chatel CNRS LCPME
2 protocols

Valentine Trotter Environmental Genomics and Systems Biology Division - Lawrence Berkeley National Laboratory
41 protocols

Alexander B Westbye
  • Post-Doc, Department of Marine Microbiology and Biogeochemistry, NIOZ Royal Netherlands Institute for Sea Research, Netherlands
Research focus
  • Microbiology
  • Prokaryotic physiology, genetics and gene flow
Contributions
  • 1 Author merit
  • 5 Reviewer merit

Education

PhD, The University of British Columbia

Publications

The SOS Response Master Regulator LexA Regulates the Gene Transfer Agent of Rhodobacter capsulatus and Represses Transcription of the Signal Transduction Protein CckA.
Kuchinski KS, Brimacombe CA, Westbye AB, Ding H, Beatty JT.
J Bacteriol. 2016 Feb 1;198(7):1137-48. doi: 10.1128/JB.00839-15.

The Gene Transfer Agent RcGTA Contains Head Spikes Needed for Binding to the Rhodobacter capsulatus Polysaccharide Cell Capsule.
Westbye AB, Kuchinski K, Yip CK, Beatty JT.
J Mol Biol. 2016 Jan 29;428(2 Pt B):477-91. doi: 10.1016/j.jmb.2015.12.010.

Gene co-expression network analysis in Rhodobacter capsulatus and application to comparative expression analysis of Rhodobacter sphaeroides.
Peña-Castillo L, Mercer RG, Gurinovich A, Callister SJ, Wright AT, Westbye AB, Beatty JT, Lang AS.
BMC Genomics. 2014 Aug 28;15:730. doi: 10.1186/1471-2164-15-730.

Phosphate concentration and the putative sensor kinase protein CckA modulate cell lysis and release of the Rhodobacter capsulatus gene transfer agent.
Westbye AB, Leung MM, Florizone SM, Taylor TA, Johnson JA, Fogg PC, Beatty JT.
J Bacteriol. 2013 Nov;195(22):5025-40. doi: 10.1128/JB.00669-13.

One for all or all for one: heterogeneous expression and host cell lysis are key to gene transfer agent activity in Rhodobacter capsulatus.
Fogg PC, Westbye AB, Beatty JT.
PLoS One. 2012;7(8):e43772. doi: 10.1371/journal.pone.0043772.

1 Protocol published
Endolysin Expression, Purification and Activity Determination by Zymography
Authors:  Alexander B. Westbye, Paul C. Fogg and John Thomas Beatty, date: 08/20/2014, view: 5016, Q&A: 0
Endolysins are peptidoglycan-degrading (muralytic) enzymes produced by many bacteriophages for cell lysis of the host bacterium. The enzymatic activity of muralytic enzymes can be assayed qualitatively using a zymogram containing incorporated ...
5 Protocols reviewed
Adhesion and Invasion Assay Procedure Using Caco-2 Cells for Listeria monocytogenes
Authors:  Swetha Reddy and Frank Austin, date: 05/05/2017, view: 1036, Q&A: 0
Listeria monocytogenes is an important Gram-positive foodborne pathogen that is a particular problem in ready-to-eat food. It has an ability to survive in harsh conditions like refrigeration temperatures and high salt concentrations and is ...
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Preparation of Purified Gram-positive Bacterial Cell Wall and Detection in Placenta and Fetal Tissues
Authors:  Beth Mann, Lip Nam Loh, Geli Gao and Elaine Tuomanen, date: 12/05/2016, view: 1688, Q&A: 0
Cell wall is a complex biopolymer on the surface of all Gram-positive bacteria. During infection, cell wall is recognized by the innate immune receptor Toll-like receptor 2 causing intense inflammation and tissue damage. In animal models, cell wall ...
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