Search
Coauthors
Ana Espinosa-Oliva Departamento de Bioquímica y Biología Molecular, Universidad de Sevilla, Spain
1 protocol

Rocío de Pablos Departamento de Bioquímica y Biología Molecular, Universidad de Sevilla, Spain
1 protocol
Coreviewers
Adler Dillman Department of Nematology, University of California, USA
7 protocols

Edgar Soria-Gomez U1215 INSERM Neurocentre Magendie, University of Bordeaux, France
6 protocols

Jyotiska Chaudhuri The Buck Institute for Research on Aging
17 protocols

Shravani Mukherjee Stanford University
4 protocols

Manuel Sarmiento Soto
  • Departamento de Bioquímica y Biología Molecular, Universidad de Sevilla, Spain
Research focus
  • Cancer biology
Contributions
  • 1 Author merit
  • 7 Reviewer merit

Education

Ph.D. in Biochemistry, Department of Biochemistry University of Seville, Spain, 2010

Current position

Postdoc in Department of Oncology, University of Oxford, UK

Publications

  1. Serres, S., Martin, C. J., Sarmiento Soto, M., Bristow, C., O'Brien, E. R., Connell, J. J., Khrapitchev, A. A. and Sibson, N. R. (2014). Structural and functional effects of metastases in rat brain determined by multimodal MRI. Int J Cancer 134(4): 885-896.
  2. Soto, M. S., Serres, S., Anthony, D. C. and Sibson, N. R. (2014). Functional role of endothelial adhesion molecules in the early stages of brain metastasis. Neuro-oncology 16(4): 540-551.
  3. Espinosa-Oliva, A. M., de Pablos, R. M., Sarmiento, M., Villarán, R. F., Carrillo-Jiménez, A., Santiago, M., Venero, J. L., Herrera, A. J., Cano, J. and Machado, A. (2014). Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures. Neurotoxicology 41: 89-101.
  4. O’Brien, E. R., Kersemans, V., Tredwell, M., Checa, B., Serres, S., Soto, M. S., Gouverneur, V., Leppert, D., Anthony, D. C. and Sibson, N. R. (2014). Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker. J Nucl Med 55(2): 275-280.
  5. de Pablos, R. M., Herrera, A. J., Espinosa-Oliva, A. M., Sarmiento, M., Muñoz, M. F., Machado, A. and Venero, J. L. (2014). Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation. J Neuroinflamm 11(1): 34.
  6. Wang, Y.1,10, Bu, F.2,3,10, Royer, C.1, Serres, S.4, Larkin, J. R.4, Soto, M. S.4, Sibson, N. R.4, Salter, V.1, Fritzsche, F.1,5 and Turnquist, C.1 (2014). ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Nat Cell Biol  16, 1092–1104.
  7. Serres, S., Bristow, C., de Pablos, R. M., Merkler, D., Soto, M. S., Sibson, N. R. and Anthony, D. C. (2013). Magnetic resonance imaging reveals therapeutic effects of interferon-beta on cytokine-induced reactivation of rat model of multiple sclerosis. J Cerebr Blood F Met 33(5): 744-753.
  8. Hernandez-Romero, M. C.*, Delgado-Cortes, M. J.*, Sarmiento, M., de Pablos, R. M., Espinosa-Oliva, A. M., Arguelles, S., Bandez, M. J., Villaran, R. F., Maurino, R., Santiago, M., Venero, J. L., Herrera, A. J., Cano, J. and Machado, A. (2012). Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system. Neurotoxicology 33(3): 347-360.
  9. Serres, S., Soto, M. S., Hamilton, A., McAteer, M. A., Carbonell, W. S., Robson, M. D., Ansorge, O., Khrapitchev, A., Bristow, C. and Balathasan, L. (2012). Molecular MRI enables early and sensitive detection of brain metastases. P Natl Acad Sci 109(17): 6674-6679.
  10. Machado, A., Herrera, A. J., Venero, J. L., Santiago, M., de Pablos, R. M., Villaran, R. F., Espinosa-Oliva, A. M., Arguelles, S., Sarmiento, M., Delgado-Cortes, M. J., Maurino, R. and Cano, J. (2011). Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons. ISRN Neurol 2011: 476158.
  11. Machado, A., Herrera, A. J., Venero, J. L., Santiago, M., De Pablos, R. M., Villaran, R. F., Espinosa-Oliva, A. M., Arguelles, S., Sarmiento, M., Delgado-Cortes, M. J., Maurino, R. and Cano, J. (2011). Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in Parkinson's disease incidence. Parkinsons Dis 2011: 393769.
  12. Villaran, R. F.*, Espinosa-Oliva, A. M.*, Sarmiento, M.*, De Pablos, R. M., Arguelles, S., Delgado-Cortes, M. J., Sobrino, V., Van Rooijen, N., Venero, J. L., Herrera, A. J., Cano, J. and Machado, A. (2010). Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease. J Neurochem 114(6): 1687-1700.
  13. Ana, M. Espinosa Oliva, de Pablos R. M., Villarán R. F., Sarmiento S., Herrera, A. J. y and Machado A. (2010). Proaging effects of stress. A review. Approaches to Aging Control 14, 33-54.
  14. Ribas-Salgueiro, J. L., Matarredona, E. R., Sarmiento, M., Ribas, J. and Pásaro, R. (2009). Respiratory response to systemic inhibition of the Na+/H+ exchanger type 3 in intact rats. Resp Physiol Neurobi 165(2): 254-260.
1 Protocol published
Creating a Rat Model of Chronic Variate Stress
Authors:  Rocío M. de Pablos, Manuel Sarmiento and Ana María Espinosa-Oliva, date: 12/05/2014, view: 3556, Q&A: 0
Stress is a condition of human experience and an important factor in the onset of various diseases. There are numerous studies showing how stress can accelerate cell aging, immune senescence and some age-related diseases such as neurodegenerative ...
7 Protocols reviewed
Locomotor Assay in Drosophila melanogaster
Authors:  Qingqing Liu, Jingsong Tian, Xing Yang, Yan Li and Aike Guo, date: 05/20/2017, view: 884, Q&A: 0
This protocol describes a simple locomotor assay in Drosophila melanogaster. In brief, the locomotor of each single fly in the culture dish is recorded by a web camera. The moving time, walking length, speed and the locomotor trails of the ...
More >
Olfactory Cued Learning Paradigm
Sensory stimulation leads to structural changes within the CNS (Central Nervous System), thus providing the fundamental mechanism for learning and memory. The olfactory circuit offers a unique model for studying experience-dependent plasticity, ...
More >