Search
Coauthors
Dawn Bignell Department of Biology, Memorial University of Newfoundland, Canada
1 protocol

Reviewer
Luke Bown
  • Ph.D Student, Memorial University of Newfoundland
Research focus
  • Microbiology
  • Streptomyces, natural products
  • 1 Author merit

Education

B. Sc. (Hons), Memorial University of Newfoundland, 2014

Publications

Bown, L. †, Srivastava, S.K. †, Piercey, B.M. †, McIsaac, C.K., Tahlan, K. (2017). Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets and Associated Mechanisms of Resistance. The Journal of Membrane Biology: 1-13. (†Co-first authors)

Bown, L. & Bignell, D.R.D. (2017). Draft Genome Sequence of the Plant Pathogen Streptomyces sp. 11-1-2. Genome Announcements 5(37): e00968-17.

Bown,L., Li, Y., Berrue, F., Verhoeven, J., Dufour, S. and Bignell, D. (2017). Biosynthesis and evolution of coronafacoyl phytotoxin production in the common scab pathogen Streptomyces scabies. Applied and Environmental Microbiology, AEM-01169.

Bown, L. & Bignell, D.R. (2017). Purification of N-coronafacoyl Phytotoxins from Streptomyces scabies. Bio-protocol 7(7): e2214. DOI: 10.21769/BioProtoc.2214.

Hynes, A., Shakya, M., Mercer, R., Grüll, M., Bown, L., Davidson, F., Steffen, E., Matchem, H., Peach, M., Berger, T., Grebe, K., Zhaxybayeva, O. & Lang, A. (2016). Functional and evolutionary characterization of a gene transfer agent’s multi-locus “genome”. Molecular Biology and Evolution, 33(10): 2530-2543.

Bown, L.†, Altowairish, M.†, Fyans, J.K. & Bignell, D.R.D. (2016). Production of the Streptomyces scabies coronafacoyl phytotoxins involves a novel biosynthetic pathway with an F420-dependent oxidoreductase and a short-chain dehydrogenase/reductase. Molecular Microbiology, 101(1): 122-135. (†Co-first authors)

Fyans, J.K.†, Bown, L.† & Bignell, D.R.D. (2016). Isolation and characterization of plant pathogenic Streptomyces species associated with common scab-infected potato tubers in Newfoundland. Phytopathology, 106(2): 123-131. (†Co-first authors)

Cheng, Z., Bown, L., Tahlan, K. & Bignell, D.R.D. (2015). Regulation of coronafacoyl phytotoxin production by the PAS-LuxR family regulator CfaR in the common scab pathogen Streptomyces scabies. Plos ONE, 10(3): e0122450.

1 Protocol published
Purification of N-coronafacoyl Phytotoxins from Streptomyces scabies
Authors:  Luke Bown and Dawn R. D. Bignell, date: 04/05/2017, view: 1225, Q&A: 0
This procedure is used for large-scale purification of N-coronafacoyl phytotoxins that are produced by the potato common scab pathogen Streptomyces scabies. The procedure employs organic extraction of S. scabies culture ...