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Coauthors
Dan Littman The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, USA
1 protocol

Reviewer
Mickaël Mathieu Ménager
  • Group leader, Institut Imagine
Research focus
  • Immunology
  • Inflammatory diseases, Transcriptomic Networks, HIV
Contributions
  • 1 Author merit
  • 1 Reviewer merit

Education

PhD

Lab information

Mickael Menager Lab

Publications

Ménager MM, Littman DR. Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell. (2016) Jan 27. pii: S0092-8674(15)01700-6. doi: 10.1016/j.cell.2015.12.036. [Epub ahead of print]. PMID:26830877

Côte M*, Ménager MM*, Burgess A, Mahlaoui N, Picard C, Schaffner C, Al-Manjomi F, Al-Harbi M, Alangari A, Le Deist F, Gennery AR, Prince N, Cariou A, Nitschke P, Blank U, El-Ghazali G, Ménasché G, Latour S, Fischer A, de Saint Basile G. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest. (2009) Dec;119(12):3765-73. doi: 10.1172/JCI40732. Epub 2009 Nov 2. PMID: 19884660 (* Co-first-authors).

Ménasché G*, Ménager MM*, Lefebvre JM, Deutsch E, Athman R, Lambert N, Mahlaoui N, Court M, Garin J, Fischer A, de Saint Basile G. A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion. Blood. (2008) Dec 15;112(13):5052-62. Epub 2008 Sep 23. PMID: 18812475. (* Co-first-authors).

Ménager MM, Ménasché G, Romao M, Knapnougel P, Ho CH, Garfa M, Raposo G, Feldmann J, Fischer A, de Saint Basile G. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol. (2007) Mar;8(3):257-67. Epub 2007 Jan 21.PMID: 17237785

1 Protocol published
Quantitative Measurements of HIV-1 and Dextran Capture by Human Monocyte-derived Dendritic Cells (MDDCs)
Authors:  Mickaël M. Ménager and Dan R. Littman, date: 11/20/2016, view: 2019, Q&A: 0
The aim of this protocol is to describe how to measure and quantify the amount of HIV-1 particles and dextran molecules internalized in human monocyte derived dendritic cells (MDDCs), using three different techniques: flow cytometry, quantitative ...