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Coauthors
Jerry Shay Department of Cell Biology, University of Texas Southwestern Medical Center, USA
3 protocols
Coreviewers
Amriti Lulla Fox Chase Cancer Center
1 protocol

Ana Santos Almeida APC Microbiome Institute, University College Cork
2 protocols

ilgen Middle name Mender
  • Department of Cell Biology, University of Texas Southwestern Medical Center, USA
Research focus
  • Cancer biology
  • Provide 3 or more keywords about your research focus.
Contributions
  • 3 Author merit
  • 2 Reviewer merit

Education

Highest academic degree, College or university

Lab information

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Publications

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3 Protocols published
Telomere Restriction Fragment (TRF) Analysis
Authors:  Ilgen Mender and Jerry W. Shay, date: 11/20/2015, view: 5333, Q&A: 0
While telomerase is expressed in ~90% of primary human tumors, most somatic tissue cells except transiently proliferating stem-like cells do not have detectable telomerase activity (Shay and Wright, 1996; Shay and Wright, 2001). Telomeres ...
Telomerase Repeated Amplification Protocol (TRAP)
Authors:  Ilgen Mender and Jerry W. Shay, date: 11/20/2015, view: 4896, Q&A: 1
Telomeres are found at the end of eukaryotic linear chromosomes, and proteins that bind to telomeres protect DNA from being recognized as double-strand breaks thus preventing end-to-end fusions (Griffith et al., 1999). However, due to the ...
2 Protocols reviewed
Intracaecal Orthotopic Colorectal Cancer Xenograft Mouse Model
Authors:  Hsin-Wei Liao and Mien-Chie Hung, date: 06/05/2017, view: 775, Q&A: 0
The host microenvironment plays a prominent role in tumor growth, angiogenesis, invasion, metastasis, and response to therapy. Orthotopic tumor model mimics the natural environment of tumor development and provides an effective approach to ...
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