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Coauthors
Fanghui Lu Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children’s Hospital Medical Center, USA
1 protocol

Ravinder Verma Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children’s Hospital Medical Center, USA
1 protocol

Qing Richard Lu
  • Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children’s Hospital Medical Center, USA
  • 1 Author merit

Education

Ph.D, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA, 1997

Current position

Scientific Director, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, USA

Professor, Department of Pediatrics, University of Cincinnati, USA

Publications

  1. Wang, H., Moyano, A. L., Ma, Z., Deng, Y., Lin, Y., Zhao, C., Zhang, L., Jiang, M., He, X., Ma, Z., Lu, F., Xin, M., Zhou, W., Yoon, S. O., Bongarzone, E. R. and Lu, Q. R. (2017). miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS. Dev Cell 40(6): 566-582 e565.
  2. Deng, Y., Wu, L., Bai, S., Zhao, C., Wang, H., Wang, J., Xu, L., Zhou, W., Xin, M. and Lu, Q. R. (2017). A Reciprocal Regulatory Loop Between TAZ/YAP and G protein Gαs Regulates Schwann Cell Proliferation and Differentiation. Nature Commun 8: 15161.
  3. He, D., Wang, J., Lu, Y., Deng, Y., Zhao, C., Xu, L., Chen, Y., Hu, Y. C., Zhou, W. and Lu, Q. R. (2017). lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS. Neuron 93(2): 362-378.
  4. Jiang, M., Liu, L., He, X., Wang, H., Lin, W., Wang, H., Yoon, S. O., Wood, T. L. and Lu, Q. R. (2016). Regulation of PERK-eIF2α Signaling by Tuberous Sclerosis Complex-1 Controls Homeostasis and Survival of Myelinating Oligodendrocytes. Nat Commun 7: 12185.
  5. Wu, L. M., Wang, J., Conidi, A., Zhao, C., Wang, H., Ford, Z., Zhang, L., Zweier, C., Ayee, B. G., Maurel, P., Zwijsen, A., Chan, J. R., Jankowski, M. P., Huylebroeck, D. and Lu, Q. R. (2016). Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination. Nat Neurosci 19(8): 1060-1072.
  6. Lu, F., Chen, Y., Zhao, C., Wang, H., He, D., Xu, L., Wang, J., He, X., Deng, Y., Lu, E. E., Liu, X., Verma, R., Bu, H., Drissi, R., Fouladi, M., Stemmer-Rachamimov, A. O., Burns, D., Xin, M., Rubin, J. B., Bahassi el, M., Canoll, P., Holland, E. C. and Lu, Q. R. (2016). Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell 29(5): 669-683.
  7. He, D., Marie, C., Zhao, C., Kim, B., Wang, J., Deng, Y., Clavairoly, A., Frah, M., Wang, H., He, X., Hmidan, H., Jones, B. V., Witte, D., Zalc, B., Zhou, X., Choo, D. I., Martin, D. M., Parras, C. and Lu, Q. R. (2016). Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Nat Neurosci 19(5): 678-689.
  8. Zhao, C., Deng, Y., Liu, L., Yu, K., Zhang, L., Wang, H., He, X., Wang, J., Lu, C., Wu, L. N., Weng, Q., Mao, M., Li, J., van Es, J. H., Xin, M., Parry, L., Goldman, S. A., Clevers, H. and Lu, Q. R. (2016). Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nat Commun 7: 10883.
  9. Zhang, L., He, X., Liu, L., Jiang, M., Zhao, C., Wang, H., He, D., Zheng, T., Zhou, X., Hassan, A., Ma, Z., Xin, M., Sun, Z., Lazar, M. A., Goldman, S. A., Olson, E. N. and Richard Lu, Q. (2016). Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. Dev Cell 37(6): 582.
  10. He, X., Zhang, L., Chen, Y., Remke, M., Shih, D., Lu, F., Wang, H., Deng, Y., Yu, Y., Xia, Y., Wu, X., Ramaswamy, V., Hu, T., Wang, F., Zhou, W., Burns, D. K., Kim, S. H., Kool, M., Pfister, S. M., Weinstein, L. S., Pomeroy, S. L., Gilbertson, R. J., Rubin, J. B., Hou, Y., Wechsler-Reya, R., Taylor, M. D. and Lu, Q. R. (2014). The G protein alpha subunit Galphas is a tumor suppressor in Sonic hedgehog-driven medulloblastoma. Nat Med 20(9): 1035-1042.
  11. Yu, Y., Chen, Y., Kim, B., Wang, H., Zhao, C., He, X., Liu, L., Liu, W., Wu, L. M., Mao, M., Chan, J. R., Wu, J. and Lu, Q. R. (2013). Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell 152(1-2): 248-261.
1 Protocol published
Glioma Induction by Intracerebral Retrovirus Injection
Authors:  Ravinder K Verma , Fanghui Lu and Qing Richard Lu, date: 07/20/2017, view: 1027, Q&A: 0
Glioblastoma (GBM) is the most common primary brain cancer in adults and has a poor prognosis. It is characterized by a high degree of cellular infiltration that leads to tumor recurrence, atypical hyperplasia, necrosis, and angiogenesis. Despite ...