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Niraj Tolia Department of Molecular Microbiology, Washington University in St. Louis, USA
2 protocols

John Jimah Department of Molecular Microbiology, Washington University in St. Louis, USA
2 protocols

Paul H Schlesinger
  • Department of Cell Biology and Physiology, Washington University in St. Louis, USA
  • 2 Author merit
2 Protocols published
Liposome Disruption Assay to Examine Lytic Properties of Biomolecules
Authors:  John R. Jimah, Paul H. Schlesinger and Niraj H. Tolia, date: 08/05/2017, view: 1226, Q&A: 0
Proteins may have three dimensional structural or amino acid features that suggest a role in targeting and disrupting lipids within cell membranes. It is often necessary to experimentally investigate if these proteins and biomolecules are able to ...
Membrane Lipid Screen to Identify Molecular Targets of Biomolecules
Authors:  John R. Jimah, Paul H. Schlesinger and Niraj H. Tolia, date: 08/05/2017, view: 1100, Q&A: 0
Proteins that bind to and disrupt cell membranes may target specific phospholipids. Here we describe a protocol to identify the lipid targets of proteins and biomolecules. First, we describe a screen to identify lipids in membranes that are ...