Mark Burns Department of Neuroscience, Georgetown University, United States, United States,
1 protocol

Italo Mocchetti Department of Neuroscience, Georgetown University, United States, United States,
1 protocol

David Loane Department of Anesthesiology, Center for Shock, Trauma, and Anesthesiology Research (STAR), University of Maryland School of Medicine, United States, United States,
1 protocol

Maria Fe Lanfranco Department of Neuroscience, Georgetown University, United States, United States,
1 protocol

Sonia Villapol
  • Department of Neuroscience, Georgetown University, United States, United States,
  • 1 Author merit


Ph.D., Autonomous University of Barcelona, Spain, 2007

Current position

Assistant Professor, Neuroscience, Georgetown University , USA


  3. De Magalhaes Filho, C. D., Kappeler, L., Dupont, J., Solinc, J., Villapol, S., Denis, C., Nosten-Bertrand, M., Billard, J. M., Blaise, A., Tronche, F., Giros, B., Charriaut-Marlangue, C., Aid, S., Le Bouc, Y. and Holzenberger, M. (2017). Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin. J Cereb Blood Flow Metab 37(2): 396-412.
  4. Barrett, J. P., Henry, R. J., Villapol, S., Stoica, B. A., Kumar, A., Burns, M. P., Faden, A. I. and Loane, D. J. (2017). NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. J Neuroinflammation 14(1): 65.
  5. Neustadtl, A. L., Winston, C. N., Parsadanian, M., Main, B. S., Villapol, S. and Burns, M. P. (2017). Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity. Neuroreport 28(10): 618-624.
  6. Main, B. S., Sloley, S. S., Villapol, S., Zapple, D. N. and Burns, M. P. (2017). A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury. J Vis Exp(124).
  7. Zhou, J., Burns, M. P., Huynh, L., Villapol, S., Taub, D. D., Saavedra, J. M. and Blackman, M. R. (2017). Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice. Front Endocrinol (Lausanne) 8: 231.
  8. Villapol, S. (2017). Roles of Peroxisome Proliferator-Activated Receptor Gamma on Brain and Peripheral Inflammation. Cell Mol Neurobiol.
  9. Villapol, S., Loane, D. J. and Burns, M. P. (2017). Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia 65(9): 1423-1438.
  10. Winston, C. N., Noel, A., Neustadtl, A., Parsadanian, M., Barton, D. J., Chellappa, D., Wilkins, T. E., Alikhani, A. D., Zapple, D. N., Villapol, S., Planel, E. and Burns, M. P. (2016). Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. Am J Pathol 186(3): 552-567.
  11. Villapol, S. (2016). Consequences of hepatic damage after traumatic brain injury: current outlook and potential therapeutic targets. Neural Regen Res 11(2): 226-227.
  12. Allen, M., Ghosh, S., Ahern, G. P., Villapol, S., Maguire-Zeiss, K. A. and Conant, K. (2016). Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1. Sci Rep 6: 35497.
  13. Washington, P. M., Villapol, S. and Burns, M. P. (2016). Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy? Exp Neurol 275 Pt 3: 381-388.
  14. Villapol, S. and Saavedra, J. M. (2015). Neuroprotective effects of angiotensin receptor blockers. Am J Hypertens 28(3): 289-299.
  15. Villapol, S., Balarezo, M. G., Affram, K., Saavedra, J. M. and Symes, A. J. (2015). Neurorestoration after traumatic brain injury through angiotensin II receptor blockage. Brain 138(Pt 11): 3299-3315.
  16. Villapol, S., Kryndushkin, D., Balarezo, M. G., Campbell, A. M., Saavedra, J. M., Shewmaker, F. P. and Symes, A. J. (2015). Hepatic expression of serum amyloid A1 is induced by traumatic brain injury and modulated by telmisartan. Am J Pathol 185(10): 2641-2652.
1 Protocol published
Combination of Fluorescent in situ Hybridization (FISH) and Immunofluorescence Imaging for Detection of Cytokine Expression in Microglia/Macrophage Cells
Authors:  Maria Fe Lanfranco, David J. Loane, Italo Mocchetti, Mark P. Burns and Sonia Villapol, date: 11/20/2017, view: 52, Q&A: 0
Microglia and macrophage cells are the primary producers of cytokines in response to neuroinflammatory processes. But these cytokines are also produced by other glial cells, endothelial cells, and neurons. It is essential to identify the cells that ...