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Coauthors
Sugi Panneerselvam Rice University, USA
1 protocol

Brandon Pekarek Department of Molecular and Human Genetics, Baylor College of Medicine, USA
1 protocol

Jessica Swanson Department of Molecular and Human Genetics, Baylor College of Medicine, USA
1 protocol

Burak Tepe Program in Developmental Biology, Baylor College of Medicine, USA
1 protocol

Benjamin Russell Arenkiel
  • Program in Developmental Biology, Baylor College of Medicine, USA
Contributions
  • 1 Author merit

Education

Ph.D, University of Utah School of Medicine, USA, 2004

Current position

Associate Professor, Department of Molecular & Human Genetics with joint appointments in the Department of Neurobiology and the Neurological Research Institute at Texas Children’s Hospital, Baylor College of Medicine, USA

Publications (since2012)

  1. John Lin, C. C., Yu, K., Hatcher, A., Huang, T. W., Lee, H. K., Carlson, J., Weston, M. C., Chen, F., Zhang, Y., Zhu, W., Mohila, C. A., Ahmed, N., Patel, A. J., Arenkiel, B. R., Noebels, J. L., Creighton, C. J. and Deneen, B. (2017). Identification of diverse astrocyte populations and their malignant analogs. Nat Neurosci 20(3): 396-405.
  2. Quast, K. B., Ung, K., Froudarakis, E., Huang, L., Herman, I., Addison, A. P., Ortiz-Guzman, J., Cordiner, K., Saggau, P., Tolias, A. S. and Arenkiel, B. R. (2017). Developmental broadening of inhibitory sensory maps. Nat Neurosci 20(2): 189-199.
  3. Yang, K., Broussard, J. I., Levine, A. T., Jenson, D., Arenkiel, B. R. and Dani, J. A. (2017). Dopamine receptor activity participates in hippocampal synaptic plasticity associated with novel object recognition. Eur J Neurosci 45(1): 138-146.
  4. Herman, A. M., Ortiz-Guzman, J., Kochukov, M., Herman, I., Quast, K. B., Patel, J. M., Tepe, B., Carlson, J. C., Ung, K., Selever, J., Tong, Q. and Arenkiel, B. R. (2016). A cholinergic basal forebrain feeding circuit modulates appetite suppression. Nature 538(7624): 253-256.
  5. Huang, L., Ung, K., Garcia, I., Quast, K. B., Cordiner, K., Saggau, P. and Arenkiel, B. R. (2016). Task Learning Promotes Plasticity of Interneuron Connectivity Maps in the Olfactory Bulb. J Neurosci 36(34): 8856-8871.
  6. Lu, H., Ash, R. T., He, L., Kee, S. E., Wang, W., Yu, D., Hao, S., Meng, X., Ure, K., Ito-Ishida, A., Tang, B., Sun, Y., Ji, D., Tang, J., Arenkiel, B. R., Smirnakis, S. M. and Zoghbi, H. Y. (2016). Loss and Gain of MeCP2 Cause Similar Hippocampal Circuit Dysfunction that Is Rescued by Deep Brain Stimulation in a Rett Syndrome Mouse Model. Neuron 91(4): 739-747.
  7. Huang, T. W., Kochukov, M. Y., Ward, C. S., Merritt, J., Thomas, K., Nguyen, T., Arenkiel, B. R. and Neul, J. L. (2016). Progressive Changes in a Distributed Neural Circuit Underlie Breathing Abnormalities in Mice Lacking MeCP2. J Neurosci 36(20): 5572-5586.
  8. Broussard, J. I., Yang, K., Levine, A. T., Tsetsenis, T., Jenson, D., Cao, F., Garcia, I., Arenkiel, B. R., Zhou, F. M., De Biasi, M. and Dani, J. A. (2016). Dopamine Regulates Aversive Contextual Learning and Associated In Vivo Synaptic Plasticity in the Hippocampus. Cell Rep 14(8): 1930-1939.
  9. Garcia, I., Bhullar, P. K., Tepe, B., Ortiz-Guzman, J., Huang, L., Herman, A. M., Chaboub, L., Deneen, B., Justice, N. J. and Arenkiel, B. R. (2016). Local corticotropin releasing hormone (CRH) signals to its receptor CRHR1 during postnatal development of the mouse olfactory bulb. Brain Struct Funct 221(1): 1-20.
  10. Soiza-Reilly, M., Saggau, P. and Arenkiel, B. R. (2015). Neural circuits revealed. Front Neural Circuits 9: 35.
  11. Lee, H. K., Laug, D., Zhu, W., Patel, J. M., Ung, K., Arenkiel, B. R., Fancy, S. P., Mohila, C. and Deneen, B. (2015). Apcdd1 stimulates oligodendrocyte differentiation after white matter injury. Glia 63(10): 1840-1849.
  12. Justice, N. J., Huang, L., Tian, J. B., Cole, A., Pruski, M., Hunt, A. J., Jr., Flores, R., Zhu, M. X., Arenkiel, B. R. and Zheng, H. (2015). Posttraumatic stress disorder-like induction elevates beta-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses. J Neurosci 35(6): 2612-2623.
  13. Wu, Z., Kim, E. R., Sun, H., Xu, Y., Mangieri, L. R., Li, D. P., Pan, H. L., Xu, Y., Arenkiel, B. R. and Tong, Q. (2015). GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. J Neurosci 35(8): 3312-3318.
  14. Murphey, D. K., Herman, A. M. and Arenkiel, B. R. (2014). Dissecting inhibitory brain circuits with genetically-targeted technologies. Front Neural Circuits 8: 124.
  15. Garcia, I., Quast, K. B., Huang, L., Herman, A. M., Selever, J., Deussing, J. M., Justice, N. J. and Arenkiel, B. R. (2014). Local CRH signaling promotes synaptogenesis and circuit integration of adult-born neurons. Dev Cell 30(6): 645-659.
  16. Wang, M., Perova, Z., Arenkiel, B. R. and Li, B. (2014). Synaptic modifications in the medial prefrontal cortex in susceptibility and resilience to stress. J Neurosci 34(22): 7485-7492.
  17. Herman, A. M., Huang, L., Murphey, D. K., Garcia, I. and Arenkiel, B. R. (2014). Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2. Elife 3: e01481.
  18. Xu, Y., Wu, Z., Sun, H., Zhu, Y., Kim, E. R., Lowell, B. B., Arenkiel, B. R., Xu, Y. and Tong, Q. (2013). Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation. Cell Metab 18(6): 860-870.
  19. Garcia, I., Kim, C. and Arenkiel, B. R. (2013). Revealing neuronal circuitry using stem cell-derived neurons. Curr Protoc Stem Cell Biol Chapter 2: Unit 2D 15.
  20. Huang, L., Garcia, I., Jen, H. I. and Arenkiel, B. R. (2013). Reciprocal connectivity between mitral cells and external plexiform layer interneurons in the mouse olfactory bulb. Front Neural Circuits 7: 32.
  21. Takatoh, J., Nelson, A., Zhou, X., Bolton, M. M., Ehlers, M. D., Arenkiel, B. R., Mooney, R. and Wang, F. (2013). New modules are added to vibrissal premotor circuitry with the emergence of exploratory whisking. Neuron 77(2): 346-360.
  22. Garcia, I., Kim, C. and Arenkiel, B. R. (2012). Genetic strategies to investigate neuronal circuit properties using stem cell-derived neurons. Front Cell Neurosci 6: 59.
  23. Chen, Q., Cichon, J., Wang, W., Qiu, L., Lee, S. J., Campbell, N. R., Destefino, N., Goard, M. J., Fu, Z., Yasuda, R., Looger, L. L., Arenkiel, B. R., Gan, W. B. and Feng, G. (2012). Imaging neural activity using Thy1-GCaMP transgenic mice. Neuron 76(2): 297-308.
  24. Ung, K. and Arenkiel, B. R. (2012). Fiber-optic implantation for chronic optogenetic stimulation of brain tissue. J Vis Exp(68): e50004.
  25. Garcia, I., Huang, L., Ung, K. and Arenkiel, B. R. (2012). Tracing synaptic connectivity onto embryonic stem cell-derived neurons. Stem Cells 30(10): 2140-2151.
  26. Guler, A. D., Rainwater, A., Parker, J. G., Jones, G. L., Argilli, E., Arenkiel, B. R., Ehlers, M. D., Bonci, A., Zweifel, L. S. and Palmiter, R. D. (2012). Transient activation of specific neurons in mice by selective expression of the capsaicin receptor. Nat Commun 3: 746.
  27. Wulff, P. and Arenkiel, B. R. (2012). Chemical genetics: receptor-ligand pairs for rapid manipulation of neuronal activity. Curr Opin Neurobiol 22(1): 54-60.
1 Protocol published
Olfactory Cued Learning Paradigm
Sensory stimulation leads to structural changes within the CNS (Central Nervous System), thus providing the fundamental mechanism for learning and memory. The olfactory circuit offers a unique model for studying experience-dependent plasticity, ...