Alfano Luigi
  • 1 Author merit


Ph.D, Molecular Oncology and Endocrinology, University of Naples “Federico II”, Naples, Italy, 2010

Current position

Postdoc position at NCI Pascale Foundation, Naples, Italy

Publications (since 2005)

  1. Alfano, L., Costa, C., Caporaso, A., Antonini, D., Giordano, A. and Pentimalli, F. (2016). HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation. Oncotarget 7(47): 78127-78139.
  2. Alfano, L., Costa, C., Caporaso, A., Altieri, A., Indovina, P., Macaluso, M., Giordano, A. and Pentimalli, F. (2016). NONO regulates the intra-S-phase checkpoint in response to UV radiation. Oncogene 35(5): 567-576.
  3. Indovina, P., Marcelli, E., Di Marzo, D., Casini, N., Forte, I. M., Giorgi, F., Alfano, L., Pentimalli, F. and Giordano, A. (2014). Abrogating G(2)/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma. Cancer Biol Ther 15(4): 380-388.
  4. Krishnamoorthy, G. P., Guida, T., Alfano, L., Avilla, E., Santoro, M., Carlomagno, F. and Melillo, R. M. (2013). Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation. J Biol Chem 288(24): 17481-17494.
  5. Ciarcia, R., Damiano, S., Fiorito, F., Granato, G., Pagnini, F., Mastellone, V., Iovane, V., Alfano, L., Valenti, F., Florio, S. and Giordano, A. (2012). Hydrocortisone attenuates cyclosporin A-induced nephrotoxicity in rats. J Cell Biochem 113(3): 997-1004.
  6. Alfano, L., Guida, T., Provitera, L., Vecchio, G., Billaud, M., Santoro, M. and Carlomagno, F. (2010). RET is a heat shock protein 90 (HSP90) client protein and is knocked down upon HSP90 pharmacological block. J Clin Endocrinol Metab 95(7): 3552-3557.
1 Protocol published
DNA Fiber Assay upon Treatment with Ultraviolet Radiations
Authors:  Alfano Luigi, Antonio Giordano and Francesca Pentimalli, date: 06/05/2017, view: 831, Q&A: 0
Genome stability is continuously challenged by a wide range of DNA damaging factors. To promote a correct DNA repair and cell survival, cells orchestrate a coordinated and finely tuned cascade of events collectively known as the DNA damage Response ...