Alejandro Penas Molecular Biology Department, IPICYT A. C., Mexico
1 protocol

Irene Castano Molecular Biology Department, IPICYT A. C., Mexico
1 protocol

Marcela Briones-Martin-del-Campo Molecular Biology Department, IPICYT A. C., Mexico
1 protocol
Fanglian He Department of Biology, University of Pennsylvania, USA
205 protocols

Martin Kolev NHLBI, NIH, USA
9 protocols

Michael Tscherner Department of Systems Biology, Harvard Medical School, Boston, MA
3 protocols

Yanjie Li Yale University
15 protocols

Emmanuel Orta-Zavalza
  • Assistant professor, Universidad Autónoma de Ciudad Juárez
Research focus
  • Molecular biology
  • Candida, microbiome, immunology
  • 1 Author merit
  • 5 Reviewer merit


PhD, IPICYT, 2014

Lab information

Emmanuel Orta's Lab


Gutierrez-Escobedo, G., Orta-Zavalza, E., Castano, I., & De Las Penas, A. (2013). Role of glutathione in the oxidative stress response in the fungal pathogen Candida glabrata. Curr Genet, 59(3), 91-106. doi:10.1007/s00294-013-0390-1

Martinez-Jimenez, V., Ramirez-Zavaleta, C. Y., Orta-Zavalza, E., de Leon, G. D., Gutierrez-Escobedo, G., de Leon, A. P., . . . Castano, I. (2013). Sir3 Polymorphisms in Candida glabrata clinical isolates. Mycopathologia, 175(3-4), 207-219. doi:10.1007/s11046-013-9627-2

Orta-Zavalza, E., Guerrero-Serrano, G., Gutierrez-Escobedo, G., Canas-Villamar, I., Juarez-Cepeda, J., Castano, I., & De Las Penas, A. (2013). Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata. Mol Microbiol, 88(6), 1135-1148. doi:10.1111/mmi.12247

Briones-Martin-Del-Campo, M., Orta-Zavalza, E., Juarez-Cepeda, J., Gutierrez-Escobedo, G., Canas-Villamar, I., Castano, I., & De Las Penas, A. (2014). The oxidative stress response of the opportunistic fungal pathogen Candida glabrata. Rev Iberoam Micol, 31(1), 67-71. doi:10.1016/j.riam.2013.09.012

Briones-Martin-del-Campo, M., Orta-Zavalza, E., Canas-Villamar, I., Gutierrez-Escobedo, G., Juarez-Cepeda, J., Robledo-Marquez, K., . . . De Las Penas, A. (2015). The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival. Microbiology, 161(Pt 2), 300-310. doi:10.1099/mic.0.000006

Izquierdo, E., Cuevas, V. D., Fernandez-Arroyo, S., Riera-Borrull, M., Orta-Zavalza, E., Joven, J., . . . Escribese, M. M. (2015). Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways. J Immunol, 195(5), 2442-2451. doi:10.4049/jimmunol.1403045

Juarez-Cepeda, J., Orta-Zavalza, E., Canas-Villamar, I., Arreola-Gomez, J., Perez-Cornejo, G. P., Hernandez-Carballo, C. Y., . . . De Las Penas, A. (2015). The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata. Curr Genet, 61(4), 529-544. doi:10.1007/s00294-015-0473-2

Yanez-Carrillo, P., Orta-Zavalza, E., Gutierrez-Escobedo, G., Patron-Soberano, A., De Las Penas, A., & Castano, I. (2015). Expression vectors for C-terminal fusions with fluorescent proteins and epitope tags in Candida glabrata. Fungal Genet Biol, 80, 43-52. doi:10.1016/j.fgb.2015.04.020

Robledo-Marquez, K., Gutierrez-Escobedo, G., Yanez-Carrillo, P., Vidal-Aguiar, Y., Briones-Martin-Del-Campo, M., Orta-Zavalza, E., . . . Castano, I. (2016). Candida glabrata encodes a longer variant of the mating type (MAT) alpha2 gene in the mating type-like MTL3 locus, which can form homodimers. FEMS Yeast Res, 16(7). doi:10.1093/femsyr/fow082

Cuevas, V. D., Anta, L., Samaniego, R., Orta-Zavalza, E., Vladimir de la Rosa, J., Baujat, G., . . . Corbi, A. L. (2017). MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis. J Immunol. doi:10.4049/jimmunol.1601667

1 Protocol published
Catalase Activity Assay in Candida glabrata
Commensal and pathogenic fungi are exposed to hydrogen peroxide (H2O2) produced by macrophages of the host. Pathogenic fungi counteract the harmful effects of H2O2 with the enzyme catalase (EC, ...
5 Protocols reviewed
Fluorescently Labelled Aerolysin (FLAER) Labelling of Candida albicans Cells
Authors:  Sneh Lata Singh and Sneha Sudha Komath, date: 06/05/2017, view: 701, Q&A: 0
In this protocol we describe a nonradiolabelled labelling of GPI anchor in Candida albicans. The method uses a fluorescent probe to bind specifically to GPI anchors so that the level of GPI-anchored proteins at the cell surface can be ...
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Isolation of PBMCs Using Vacutainer® Cellular Preparation Tubes (CPTTM)
Authors:  Alaina Puleo, Chantia Carroll, Holden Maecker and Rohit Gupta, date: 01/20/2017, view: 3113, Q&A: 0
Peripheral blood mononuclear cell (PBMC) isolation is commonly done via density gradient centrifugation over Ficoll-Hypaque, a labor-intensive procedure that requires skilled technicians and can contribute to sample variability. Cellular Preparation ...
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