Search
Coauthors
Inna Lavrik Translational Inflammation Research, Institute of Experimental Internal Medicine, Otto von Guericke University Magdeburg, Medical Faculty, Germany
1 protocol

Jörn Buchbinder Translational Inflammation Research, Institute of Experimental Internal Medicine, Otto von Guericke University Magdeburg, Medical Faculty, Germany
1 protocol

Clara Wolfe Translational Inflammation Research, Institute of Experimental Internal Medicine, Otto von Guericke University Magdeburg, Medical Faculty, Germany
1 protocol

Sabine Pietkiewicz
  • Translational Inflammation Research, Institute of Experimental Internal Medicine, Otto von Guericke University Magdeburg, Medical Faculty, Germany
Contributions
  • 1 Author merit

Education

Dr. rer. nat. in Biology, Heinrich-Heine-University, Düsseldorf, Germany, 2012

Current Position

Member of the scientific staff, Department of evidence-based medicine, Medical advisory service of social health insurance, Essen, Germany

Publications

  1. Kasiri, M. M., Beer, L., Nemec, L., Gruber, F., Pietkiewicz, S., Haider, T., Simader, E. M., Traxler, D., Schweiger, T., Janik, S., Taghavi, S., Gabriel, C., Mildner, M. and Ankersmit, H. J. (2016). Dying blood mononuclear cell secretome exerts antimicrobial activity. Eur J Clin Invest 46(10): 853-863.
  2. Schleich, K., Buchbinder, J. H., Pietkiewicz, S., Kahne, T., Warnken, U., Ozturk, S., Schnolzer, M., Naumann, M., Krammer, P. H. and Lavrik, I. N. (2016). Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain. Cell Death Differ 23(4): 681-694.
  3. Mohle, L., Israel, N., Paarmann, K., Krohn, M., Pietkiewicz, S., Muller, A., Lavrik, I. N., Buguliskis, J. S., Schott, B. H., Schluter, D., Gundelfinger, E. D., Montag, D., Seifert, U., Pahnke, J. and Dunay, I. R. (2016). Chronic Toxoplasma gondii infection enhances beta-amyloid phagocytosis and clearance by recruited monocytes. Acta Neuropathol Commun 4: 25.
  4. Pietkiewicz, S., Eils, R., Krammer, P. H., Giese, N. and Lavrik, I. N. (2015). Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death network. Exp Cell Res 339(1): 1-9.
  5. Desiree Boehme, J., Pietkiewicz, S., Lavrik, I., Jeron, A. and Bruder, D. (2015). Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease. Lung 193(6): 947-953.
  6. Dieterle, A. M., Bohler, P., Keppeler, H., Alers, S., Berleth, N., Driessen, S., Hieke, N., Pietkiewicz, S., Loffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. and Stork, B. (2014). PDK1 controls upstream PI3K expression and PIP3 generation. Oncogene 33(23): 3043-3053.

  7. Pietkiewicz, S., Schmidt, J. H. and Lavrik, I. N. (2015). Quantification of apoptosis and necroptosis at the single cell level by a combination of Imaging Flow Cytometry with classical Annexin V/propidium iodide staining. J Immunol Methods 423: 99-103.
  8. Schmidt, J. H., Pietkiewicz, S., Naumann, M. and Lavrik, I. N. (2015). Quantification of CD95-induced apoptosis and NF-kappaB activation at the single cell level. J Immunol Methods 423: 12-17.
  9. Pietkiewicz, S., Sohn, D., Piekorz, R. P., Grether-Beck, S., Budach, W., Sabapathy, K. and Janicke, R. U. (2013). Oppositional regulation of Noxa by JNK1 and JNK2 during apoptosis induced by proteasomal inhibitors. PLoS One 8(4): e61438.
1 Protocol published
Measuring Procaspase-8 and -10 Processing upon Apoptosis Induction
Authors:  Sabine Pietkiewicz, Clara Wolfe, Jörn H. Buchbinder and Inna N. Lavrik, date: 01/05/2017, view: 1573, Q&A: 0
Apoptosis or programmed cell death is important for multicellular organisms to keep cell homeostasis and for the clearance of mutated or infected cells. Apoptosis can be induced by intrinsic or extrinsic stimuli. The first event in extrinsic ...