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Coauthors
Hiroyuki Konishi Department of Biochemistry, Aichi Medical University School of Medicine, Japan
1 protocol

Yoshitaka Hosokawa Department of Biochemistry, Aichi Medical University School of Medicine, Japan
1 protocol

Shinobu Tsuzuki Department of Biochemistry, Aichi Medical University School of Medicine, Japan
1 protocol

Md Wahiduzzaman Department of Biochemistry, Aichi Medical University School of Medicine, Japan
1 protocol

Akinobu Ota
  • Department of Biochemistry, Aichi Medical University School of Medicine, Japan
Contributions
  • 1 Author merit

Education

Ph.D in Medical Science, Sapporo Medical University, 2010

Current Position

Lecturer, Department of Biochemistry, Aichi Medical University School of Medicine, Japan

Publications (since 2010)

  1. Ito, K., Ota, A., Ono, T., Nakaoka, T., Wahiduzzaman, M., Karnan, S., Konishi, H., Furuhashi, A., Hayashi, T., Yamada, Y., Hosokawa, Y. and Kazaoka, Y. (2016). Inhibition of Nox1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines. Oncol Rep 36(5): 2991-2998.
  2. Karnan, S., Ota, A., Konishi, Y., Wahiduzzaman, M., Hosokawa, Y. and Konishi, H. (2016). Improved methods of AAV-mediated gene targeting for human cell lines using ribosome-skipping 2A peptide. Nucleic Acids Res 44(6): e54.
  3. Mizuno, S., Hanamura, I., Ota, A., Karnan, S., Narita, T., Ri, M., Mizutani, M., Goto, M., Gotou, M., Tsunekawa, N., Shikami, M., Iida, S., Hosokawa, Y., Miwa, H., Ueda, R., Nitta, M. and Takami, A. (2015). Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells. Int J Hematol 102(5): 569-578.
  4. Tanaka, M., Miura, Y., Numanami, H., Karnan, S., Ota, A., Konishi, H., Hosokawa, Y. and Hanyuda, M. (2015). Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species. Oncol Rep 34(4): 1726-1732.
  5. Ono, T., Ota, A., Ito, K., Nakaoka, T., Karnan, S., Konishi, H., Furuhashi, A., Hayashi, T., Yamada, Y., Hosokawa, Y. and Kazaoka, Y. (2015). Plumbagin suppresses tumor cell growth in oral squamous cell carcinoma cell lines. Oral Dis 21(4): 501-511.
  6. Asai, A., Karnan, S., Ota, A., Takahashi, M., Damdindorj, L., Konishi, Y., Hossain, E., Konishi, H., Nagata, A., Yokoo, K. and Hosokawa, Y. (2015). High-resolution 400K oligonucleotide array comparative genomic hybridization analysis of neurofibromatosis type 1-associated cutaneous neurofibromas. Gene 558(2): 220-226.
  7. Hossain, E., Ota, A., Karnan, S., Takahashi, M., Mannan, S. B., Konishi, H. and Hosokawa, Y. (2015). Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages. Mol Cell Biochem 400(1-2): 29-40.
  8. Damdindorj, L., Karnan, S., Ota, A., Hossain, E., Konishi, Y., Hosokawa, Y. and Konishi, H. (2014). A comparative analysis of constitutive promoters located in adeno-associated viral vectors. PLoS One 9(8): e106472.
  9. Nakaoka, T., Ota, A., Ono, T., Karnan, S., Konishi, H., Furuhashi, A., Ohmura, Y., Yamada, Y., Hosokawa, Y. and Kazaoka, Y. (2014). Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells. Cell Oncol (Dordr) 37(2): 119-129.
1 Protocol published
Efficient AAV-mediated Gene Targeting Using 2A-based Promoter-trap System
Adeno-associated virus (AAV)-based targeting vectors have 1-4-log higher gene targeting efficiencies compared with plasmid-based targeting vectors. The efficiency of AAV-mediated gene targeting is further increased by introducing a promoter-trap ...