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Coauthors
William Catherino Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, USA
1 protocol

Minnie Malik Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, USA
1 protocol

Joy Britten
  • Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, USA
Contributions
  • 1 Author merit

Education

Medical Degree in Hahnemann University School of Medicine, 1992

Current position

Lab Manager/Molecular Biologist, Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

Publications

  1. Malik, M., Britten, J., Cox, J., Patel, A. and Catherino, W. H. (2016). Gonadotropin-releasing hormone analogues inhibit leiomyoma extracellular matrix despite presence of gonadal hormones. Fertil Steril 105(1): 214-224.

  2. Patel, A., Malik, M., Britten, J., Cox, J. and Catherino, W. H. (2014). Alternative therapies in management of leiomyomas. Fertil Steril 102(3): 649-655.

  3. Malik, M., Britten, J., Segars, J. and Catherino, W. H. (2014). Leiomyoma cells in 3-dimensional cultures demonstrate an attenuated response to fasudil, a rho-kinase inhibitor, when compared to 2-dimensional cultures. Reprod Sci 21(9): 1126-1138.

  4. Levy, G., Malik, M., Britten, J., Gilden, M., Segars, J. and Catherino, W. H. (2014). Liarozole inhibits transforming growth factor-beta3--mediated extracellular matrix formation in human three-dimensional leiomyoma cultures. Fertil Steril 102(1): 272-281 e272.

  5. Britten, J. L., Malik, M., Levy, G., Mendoza, M. and Catherino, W. H. (2012). Gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate and GnRH antagonist cetrorelix acetate directly inhibit leiomyoma extracellular matrix production. Fertil Steril 98(5): 1299-1307.

  6. Gilden, M., Malik, M., Britten, J., Delgado, T., Levy, G. and Catherino, W. H. (2012). Leiomyoma fibrosis inhibited by liarozole, a retinoic acid metabolic blocking agent. Fertil Steril 98(6): 1557-1562.

  7. McCarthy-Keith, D. M., Malik, M., Britten, J., Segars, J. and Catherino, W. H. (2011). Gonadotropin-releasing hormone agonist increases expression of osmotic response genes in leiomyoma cells. Fertil Steril 95(7): 2383-2387.

  8. Malik, M., Norian, J., McCarthy-Keith, D., Britten, J. and Catherino, W. H. (2010). Why leiomyomas are called fibroids: the central role of extracellular matrix in symptomatic women. Semin Reprod Med 28(3): 169-179.

  9. Malik, M., Webb, J. and Catherino, W. H. (2008). Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells. Clin Endocrinol (Oxf) 69(3): 462-470.

  10. Gonzales, E., Chen, H., Munuve, R., Mehrani, T., Britten-Webb, J., Nadel, A., Alam, H. B., Wherry, D., Burris, D. and Koustova, E. (2006). Valproic acid prevents hemorrhage-associated lethality and affects the acetylation pattern of cardiac histones. Shock 25(4): 395-401.

  11. Lin, T., Alam, H. B., Chen, H., Britten-Webb, J., Rhee, P., Kirkpatrick, J. and Koustova, E. (2006). Cardiac histones are substrates of histone deacetylase activity in hemorrhagic shock and resuscitation. Surgery 139(3): 365-376.

  12. Jaskille, A., Koustova, E., Rhee, P., Britten-Webb, J., Chen, H., Valeri, C. R., Kirkpatrick, J. R. and Alam, H. B. (2006). Hepatic apoptosis after hemorrhagic shock in rats can be reduced through modifications of conventional Ringer's solution. J Am Coll Surg 202(1): 25-35.

  13. Seldin, M. F., Morse, H. C., 3rd, D'Hoostelaere, L., Britten, J. L. and Steinberg, A. D. (1987). Mapping of alpha-spectrin on distal mouse chromosome 1. Cytogenet Cell Genet 45(1): 52-54.

  14. Steinberg, A. D., Klinman, D. M., Kastner, D. L., Seldin, M. F., Gause, W. C., Scribner, C. L., Britten, J. L., Siegel, J. N. and Mountz, J. D. (1987). Genetic and molecular genetic studies of murine and human lupus. J Rheumatol Suppl 14 Suppl 13: 166-176.

1 Protocol published
A 3D Culture System of Human Immortalized Myometrial Cells
Authors:  Minnie Malik, Joy Britten and William H. Catherino, date: 10/20/2016, view: 1868, Q&A: 0
Myometrium forms the middle layer of the uterus and is mainly composed of the smooth muscle cells. The cells in vitro are usually grown in a single layer (2-dimensional; 2D) format, whereas in vivo cells are structured in an ...