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Coauthors
Joy Feng Gilead Sciences
2 protocols

Yili Xu
  • Department of Biology, Gilead Sciences, USA
Contributions
  • 1 Author merit

Current position

Associate Scientist I, Biochemistry Group in Biology Department, Gilead Bioscences, Foster City, CA (11/2008 to current)

Publications

  1. Feng, J. Y., Cheng, G., Perry, J., Barauskas, O., Xu, Y., Fenaux, M., Eng, S., Tirunagari, N., Peng, B., Yu, M., Tian, Y., Lee, Y. J., Stepan, G., Lagpacan, L. L., Jin, D., Hung, M., Ku, K. S., Han, B., Kitrinos, K., Perron, M., Birkus, G., Wong, K. A., Zhong, W., Kim, C. U., Carey, A., Cho, A. and Ray, A. S. (2014). Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug. Antimicrob Agents Chemother 58(4): 1930-1942.
  2. Tsiang, M., Jones, G. S., Niedziela-Majka, A., Kan, E., Lansdon, E. B., Huang, W., Hung, M., Samuel, D., Novikov, N., Xu, Y., Mitchell, M., Guo, H., Babaoglu, K., Liu, X., Geleziunas, R. and Sakowicz, R. (2012). New class of HIV-1 integrase (IN) inhibitors with a dual mode of action. J Biol Chem 287(25): 21189-21203.
  3. Arnold, J. J., Sharma, S. D., Feng, J. Y., Ray, A. S., Smidansky, E. D., Kireeva, M. L., Cho, A., Perry, J., Vela, J. E., Park, Y., Xu, Y., Tian, Y., Babusis, D., Barauskus, O., Peterson, B. R., Gnatt, A., Kashlev, M., Zhong, W. and Cameron, C. E. (2012). Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. PLoS Pathog 8(11): e1003030.
  4. Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., Bosch, F., Bose, M., Byrne, B. J., Caton, T., Chiorini, J. A., Chtarto, A., Clark, K. R., Conlon, T., Darmon, C., Doria, M., Douar, A., Flotte, T. R., Francis, J. D., Francois, A., Giacca, M., Korn, M. T., Korytov, I., Leon, X., Leuchs, B., Lux, G., Melas, C., Mizukami, H., Moullier, P., Muller, M., Ozawa, K., Philipsberg, T., Poulard, K., Raupp, C., Riviere, C., Roosendaal, S. D., Samulski, R. J., Soltys, S. M., Surosky, R., Tenenbaum, L., Thomas, D. L., van Montfort, B., Veres, G., Wright, J. F., Xu, Y., Zelenaia, O., Zentilin, L. and Snyder, R. O. (2010). Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum Gene Ther 21(10): 1273-1285.
  5. Pulkkinen, L., Meneguzzi, G., McGrath, J. A., Xu, Y., Blanchet-Bardon, C., Ortonne, J. P., Christiano, A. M. and Uitto, J. (1997). Predominance of the recurrent mutation R635X in the LAMB3 gene in European patients with Herlitz junctional epidermolysis bullosa has implications for mutation detection strategy. J Invest Dermatol 109(2): 232-237.
  6. Pulkkinen, L., Kurtz, K., Xu, Y., Bruckner-Tuderman, L. and Uitto, J. (1997). Genomic organization of the integrin beta 4 gene (ITGB4): a homozygous splice-site mutation in a patient with junctional epidermolysis bullosa associated with pyloric atresia. Lab Invest 76(6): 823-833.
  7. Pulkkinen, L., Kimonis, V. E., Xu, Y., Spanou, E. N., McLean, W. H. and Uitto, J. (1997). Homozygous alpha6 integrin mutation in junctional epidermolysis bullosa with congenital duodenal atresia. Hum Mol Genet 6(5): 669-674.
  8. Christiano, A. M., Hoffman, G. G., Zhang, X., Xu, Y., Tamai, Y., Greenspan, D. S. and Uitto, J. (1997). Strategy for identification of sequence variants in COL7A1 and a novel 2-bp deletion mutation in recessive dystrophic epidermolysis bullosa. Hum Mutat 10(5): 408-414.
1 Protocol published
Mitochondrial Biogenesis Assay after 5-day Treatment in PC-3 Cells
Authors:  Yili Xu and Joy Y. Feng, date: 01/20/2015, view: 3692, Q&A: 0
Drug-induced mitochondrial injury can be caused by many different mechanisms including inhibition of mitochondrial DNA replication, transcription, translation, and altered protein function. Determination of the level of mitochondrial protein ...