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Coauthors
Beat Bornhauser Department of Oncology and Children’s Research Center, University Children's Hospital Zurich, Switzerland
1 protocol

Jean-Pierre Bourquin Department of Oncology and Children’s Research Center, University Children’s Hospital Zurich, Switzerland
1 protocol

Pawel Pelczar Institute of Laboratory Animal Science, University of Zurich, Switzerland
1 protocol

Mario Hermann Institute of Laboratory Animal Science, University of Zurich, Switzerland
1 protocol

Adriano Aguzzi
  • Institute of Neuropathology, University Hospital of Zurich, Switzerland
  • 1 Author merit
1 Protocol published
Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
CRISPR-Cas9 based knockout strategies are increasingly used to analyze gene function. However, redundancies and overlapping functions in biological signaling pathways can call for generating multi-gene knockout cells, which remains a relatively ...