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Coauthors
Jennifer Welch Department of Microbiology, Carver College of Medicine, University of Iowa, USA
1 protocol

Marisa Madison Department of Mathematics and Natural Sciences, Miami Dade College, USA
1 protocol

Chioma M. Okeoma
  • Department of Microbiology, Carver College of Medicine, University of Iowa, USA
  • 1 Author merit

Education

Ph.D in Animal Science, Massey University, Palmerston North, New Zealand, 2006

Current position

Assistant Professor in Microbiology, University of Iowa, Iowa City, USA

Publications

  1. Welch, J. L., Madison, M. N., Margolick, J. B., Galvin, S., Gupta, P., Martinez-Maza, O., Dash, C. and Okeoma, C. M. (2017). Effect of prolonged freezing of semen on exosome recovery and biologic activity. Sci Rep 7: 45034.
  2. Mahauad-Fernandez, W. D. and Okeoma, C. M. (2017). Cysteine-linked dimerization of BST-2 confers anoikis resistance to breast cancer cells by negating proapoptotic activities to promote tumor cell survival and growth. Cell Death Dis 8(3): e2687.
  3. Madison, M. N., Jones, P. H. and Okeoma, C. M. (2015). Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex. Virology 482: 189-201.
  4. Madison, M. N. and Okeoma, C. M. (2015). Exosomes: Implications in HIV-1 Pathogenesis. Viruses 7(7): 4093-4118.
  5. Mahauad-Fernandez, W. D., Borcherding, N. C., Zhang, W. and Okeoma, C. M. (2015). Bone marrow stromal antigen 2 (BST-2) DNA is demethylated in breast tumors and breast cancer cells. PLoS One 10(4): e0123931.
  6. Madison, M. N., Roller, R. J. and Okeoma, C. M. (2014). Human semen contains exosomes with potent anti-HIV-1 activity. Retrovirology 11: 102.
  7. Mahauad-Fernandez, W. D., DeMali, K. A., Olivier, A. K. and Okeoma, C. M. (2014). Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis. Breast Cancer Res 16(6): 493.
  8. Jones, P. H., Mahauad-Fernandez, W. D., Madison, M. N. and Okeoma, C. M. (2013). BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer. Virology 444(1-2): 124-139.
  9. Jones, P. H. and Okeoma, C. M. (2013). Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated BST-2/tetherin regulation. Cell Signal 25(12): 2752-2761.
  10. Mehta, H. V., Jones, P. H., Weiss, J. P. and Okeoma, C. M. (2012). IFN-alpha and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways. J Immunol 189(8): 4088-4103.
  11. Jones, P. H., Mehta, H. V. and Okeoma, C. M. (2012). A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice. Retrovirology 9: 50.
  12. Okeoma, C. M., Huegel, A. L., Lingappa, J., Feldman, M. D. and Ross, S. R. (2010). APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions. Cell Host Microbe 8(6): 534-543.
  13. Okeoma, C. M., Petersen, J. and Ross, S. R. (2009). Expression of murine APOBEC3 alleles in different mouse strains and their effect on mouse mammary tumor virus infection. J Virol 83(7): 3029-3038.
  14. Okeoma, C. M., Low, A., Bailis, W., Fan, H. Y., Peterlin, B. M. and Ross, S. R. (2009). Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection. J Virol 83(8): 3486-3495.
  15. Okeoma, C. M., Lovsin, N., Peterlin, B. M. and Ross, S. R. (2007). APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature 445(7130): 927-930.
1 Protocol published
Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection Assays
Authors:  Marisa N. Madison, Jennifer L. Welch and Chioma M. Okeoma, date: 04/05/2017, view: 1536, Q&A: 0
Exosomes are membranous extracellular nanovesicles of endocytic origin. Exosomes are known to carry host and pathogen-derived genomic, proteomic, lipidomic cargos and other extraneous molecules. Exosomes are secreted by diverse cell types into the ...