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Coauthors
Johan Neyts KU Leuven – University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Belgium
3 protocols

Carmen Mirabelli KU Leuven – University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Belgium
1 protocol

Leen Delang KU Leuven – University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Belgium
1 protocol

Liang Sun
  • KU Leuven – University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Belgium
Contributions
  • 1 Author merit

Education

Ph.D candidate, Rega institute, KU Leuven, Belgium, 2017

Current position

Ph.D student, Virology, Rega institute, KU Leuven, Belgium

Publications

  1. Tassini, S., Sun, L., Lanko, K., Crespan, E., Langron, E., Falchi, F., Kissova, M., Armijos-Rivera, J. I., Delang, L., Mirabelli, C., Neyts, J., Pieroni, M., Cavalli, A., Costantino, G., Maga, G., Vergani, P., Leyssen, P. and Radi, M. (2017). Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases. J Med Chem 60(4): 1400-1416.
  2. Martinez-Gualda, B., Sun, L., Rivero-Buceta, E., Flores, A., Quesada, E., Balzarini, J., Noppen, S., Liekens, S., Schols, D., Neyts, J., Leyssen, P., Mirabelli, C., Camarasa, M. J. and San-Felix, A. (2017). Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid. Antiviral Res 139: 32-40.
  3. Rivero-Buceta, E., Sun, L., Martinez-Gualda, B., Doyaguez, E. G., Donckers, K., Quesada, E., Camarasa, M. J., Delang, L., San-Felix, A., Neyts, J. and Leyssen, P. (2016). Optimization of a Class of Tryptophan Dendrimers That Inhibit HIV Replication Leads to a Selective, Specific, and Low-Nanomolar Inhibitor of Clinical Isolates of Enterovirus A71. Antimicrob Agents Chemother 60(8): 5064-5067.
  4. Drenichev, M. S., Oslovsky, V. E., Sun, L., Tijsma, A., Kurochkin, N. N., Tararov, V. I., Chizhov, A. O., Neyts, J., Pannecouque, C., Leyssen, P. and Mikhailov, S. N. (2016). Modification of the length and structure of the linker of N(6)-benzyladenosine modulates its selective antiviral activity against enterovirus 71. Eur J Med Chem 111: 84-94.
  5. Sun, L., Meijer, A., Froeyen, M., Zhang, L., Thibaut, H. J., Baggen, J., George, S., Vernachio, J., van Kuppeveld, F. J., Leyssen, P., Hilgenfeld, R., Neyts, J. and Delang, L. (2015). Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother 59(12): 7782-7785.
  6. Sun, L., Sun, E. C., Yang, T., Xu, Q. Y., Feng, Y. F., Li, J. P., Sun, J., Wang, W. S., Wei, P. and Wu, D. L. (2014). In silico prediction and in vitro identification of bluetongue virus 4 VP5 protein B-cell epitopes. Appl Microbiol Biotechnol 98(7): 3033-3047.
  7. Sun, E., Zhao, J., Sun, L., Xu, Q., Yang, T., Qin, Y., Wang, W., Wei, P., Sun, J. and Wu, D. (2013). Comprehensive mapping of common immunodominant epitopes in the eastern equine encephalitis virus E2 protein recognized by avian antibody responses. PLoS One 8(7): e69349.
1 Protocol published
In vitro Assay to Assess Efficacy of Potential Antiviral Compounds against Enterovirus D68
Authors:  Liang Sun, Leen Delang, Carmen Mirabelli and Johan Neyts, date: 03/20/2017, view: 1092, Q&A: 0
In 2014 enterovirus D68 (EV-D68) caused the largest outbreak in the United States since the discovery of the virus. Distinct from before, the 2014 infections were associated with more severe respiratory disease and occasional neurological ...