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Coauthors
Matthew Albert Cancer Immunology, Genentech, USA
2 protocols

Rosa Barreira da Silva Cancer Immunology, Genentech, USA
2 protocols

Molly A. Ingersoll
  • Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, France
Contributions
  • 1 Author merit

Education

Ph.D of Microbiology, Department of Microbiology, New York University School of Medicine, New York, NY and Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany, 2005

Current position

Tenured Scientist, Team Leader, Laboratory of dendritic cell immunobiology, Department of Immunology, Institute Pasteur, Paris, France

Publications

  1. Rousseau, M., Goh, H. M., Holec, S., Albert, M. L., Williams, R. B., Ingersoll, M. A. and Kline, K. A. (2016). Bladder catheterization increases susceptibility to infection that can be prevented by prophylactic antibiotic treatment. JCI Insight 1(15): e88178.
  2. Grossman, H. B., Lamm, D. L., Kamat, A. M., Keefe, S., Taylor, J. A., 3rd and Ingersoll, M. A. (2016). Innovation in Bladder Cancer Immunotherapy. J Immunother 39(8): 291-297.
  3. Zdimerova, H., Albert, M. L. and Ingersoll, M. A. (2015). Harnessing the Host Immune Response to Infection – BCG Immunotherapy for Bladder Cancer. In: Shurin, M. R., Thanavala, Y. and Ismail, N. (Eds). Infection and Cancer: Bi-Directorial Interactions. Springer, 387-403.
  4. Cui, Y., Franciszkiewicz, K., Mburu, Y. K., Mondot, S., Le Bourhis, L., Premel, V., Martin, E., Kachaner, A., Duban, L., Ingersoll, M. A., Rabot, S., Jaubert, J., De Villartay, J. P., Soudais, C. and Lantz, O. (2015). Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation. J Clin Invest 125(11): 4171-4185.
  5. Barreira da Silva, R., Laird, M. E., Yatim, N., Fiette, L., Ingersoll, M. A. and Albert, M. L. (2015). Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol 16(8): 850-858.
  6. Mora-Bau, G., Platt, A. M., van Rooijen, N., Randolph, G. J., Albert, M. L. and Ingersoll, M. A. (2015). Macrophages Subvert Adaptive Immunity to Urinary Tract Infection. PLoS Pathog 11(7): e1005044.
  7. Rentsch, C. A., Birkhauser, F. D., Biot, C., Gsponer, J. R., Bisiaux, A., Wetterauer, C., Lagranderie, M., Marchal, G., Orgeur, M., Bouchier, C., Bachmann, A., Ingersoll, M. A., Brosch, R., Albert, M. L. and Thalmann, G. N. (2014). Bacillus Calmette-Guerin strain differences have an impact on clinical outcome in bladder cancer immunotherapy. Eur Urol 66(4): 677-688.
  8. Kamat, A. M., Vlahou, A., Taylor, J. A., Hudson, M. L., Pesch, B., Ingersoll, M. A., Todenhofer, T., van Rhijn, B., Kassouf, W., Barton Grossman, H., Behrens, T., Chandra, A., Goebell, P. J., Palou, J., Sanchez-Carbayo, M. and Schmitz-Drager, B. J. (2014). Considerations on the use of urine markers in the management of patients with high-grade non-muscle-invasive bladder cancer. Urol Oncol 32(7): 1069-1077.
  9. Schmitz-Drager, B. J., Todenhofer, T., van Rhijn, B., Pesch, B., Hudson, M. A., Chandra, A., Ingersoll, M. A., Kassouf, W., Palou, J., Taylor, J., Vlahou, A., Behrens, T., Critelli, R., Grossman, H. B., Sanchez-Carbayo, M. and Kamat, A. (2014). Considerations on the use of urine markers in the management of patients with low-/intermediate-risk non-muscle invasive bladder cancer. Urol Oncol 32(7): 1061-1068.
  10. Ingersoll, M. A. and Albert, M. L. (2013). From infection to immunotherapy: host immune responses to bacteria at the bladder mucosa. Mucosal Immunol 6(6): 1041-1053.
  11. Perot, B. P., Ingersoll, M. A. and Albert, M. L. (2013). The impact of macroautophagy on CD8(+) T-cell-mediated antiviral immunity. Immunol Rev 255(1): 40-56.
  12. Ingersoll, M. A., Potteaux, S., Alvarez, D., Hutchison, S. B., van Rooijen, N. and Randolph, G. J. (2012). Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis. Immunobiology 217(5): 548-557.
  13. Fischer, M. A., Davies, M. L., Reider, I. E., Heipertz, E. L., Epler, M. R., Sei, J. J., Ingersoll, M. A., Rooijen, N. V., Randolph, G. J. and Norbury, C. C. (2011). CD11b(+), Ly6G(+) cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog 7(11): e1002374.
  14. Ingersoll, M. A., Platt, A. M., Potteaux, S. and Randolph, G. J. (2011). Monocyte trafficking in acute and chronic inflammation. Trends Immunol 32(10): 470-477.
  15. Kline, K. A., Ingersoll, M. A., Nielsen, H. V., Sakinc, T., Henriques-Normark, B., Gatermann, S., Caparon, M. G. and Hultgren, S. J. (2010). Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence. Infect Immun 78(5): 1943-1951.
  16. Ingersoll, M. A., Spanbroek, R., Lottaz, C., Gautier, E. L., Frankenberger, M., Hoffmann, R., Lang, R., Haniffa, M., Collin, M., Tacke, F., Habenicht, A. J., Ziegler-Heitbrock, L. and Randolph, G. J. (2010). Comparison of gene expression profiles between human and mouse monocyte subsets. Blood 115(3): e10-19.
  17. Bogunovic, M., Ginhoux, F., Helft, J., Shang, L., Hashimoto, D., Greter, M., Liu, K., Jakubzick, C., Ingersoll, M. A., Leboeuf, M., Stanley, E. R., Nussenzweig, M., Lira, S. A., Randolph, G. J. and Merad, M. (2009). Origin of the lamina propria dendritic cell network. Immunity 31(3): 513-525.
  18. Ingersoll, M. A., Kline, K. A., Nielsen, H. V. and Hultgren, S. J. (2008). G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity. Cell Microbiol 10(12): 2568-2578.
  19. Ingersoll, M. A. and Zychlinsky, A. (2006). ShiA abrogates the innate T-cell response to Shigella flexneri infection. Infect Immun 74(4): 2317-2327.
  20. Ingersoll, M. A., Moss, J. E., Weinrauch, Y., Fisher, P. E., Groisman, E. A. and Zychlinsky, A. (2003). The ShiA protein encoded by the Shigella flexneri SHI-2 pathogenicity island attenuates inflammation. Cell Microbiol 5(11): 797-807.
  21. Ingersoll, M., Groisman, E. A. and Zychlinsky, A. (2002). Pathogenicity islands of Shigella. Curr Top Microbiol Immunol 264(1): 49-65.
1 Protocol published
Measurement of Dipeptidylpeptidase Activity in vitro and in vivo
Authors:  Rosa Barreira da Silva, Molly A. Ingersoll and Matthew L. Albert, date: 03/20/2017, view: 1037, Q&A: 0
Dipeptidylpeptidases (DPPs) are serine proteases, which cleave small proteins and peptides possessing a proline or an alanine in the second position of their N-terminus. Among the members of this family, dipeptidylpeptidase 4 (DPP4) is ...