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Coauthors
Jeffrey Gimble Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, USA
1 protocol

Amy Strong Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, USA
1 protocol

Robert Jones Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, USA
1 protocol

Bruce A. Bunnell
  • Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, USA
Contributions
  • 1 Author merit

Education

Ph.D of microbiology (molecular genetics), University of Alabama at Birmingham, Birmingham, Alabama, 1990

Current position

Director, Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine
Professor, Department of Pharmacology, Tulane University School of Medicine
Chair, Division of Regenerative Medicine, Tulane National Primate Research Center

Publications (since 2014)

  1. Frazier, T. P., Bowles, A., Lee, S., Abbott, R., Tucker, H. A., Kaplan, D., Wang, M., Strong, A., Brown, Q., He, J., Bunnell, B. A. and Gimble, J. M. (2016). Serially Transplanted Nonpericytic CD146(-) Adipose Stromal/Stem Cells in Silk Bioscaffolds Regenerate Adipose Tissue In Vivo. Stem Cells 34(4): 1097-1111.
  2. Strong, A. L., Bowles, A. C., Wise, R. M., Morand, J. P., Dutreil, M. F., Gimble, J. M. and Bunnell, B. A. (2016). Human Adipose Stromal/Stem Cells from Obese Donors Show Reduced Efficacy in Halting Disease Progression in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. Stem Cells 34(3): 614-626.
  3. Zwezdaryk, K. J., Ferris, M. B., Strong, A. L., Morris, C. A., Bunnell, B. A., Dhurandhar, N. V., Gimble, J. M. and Sullivan, D. E. (2016). Human cytomegalovirus infection of human adipose-derived stromal/stem cells restricts differentiation along the adipogenic lineage. Adipocyte 5(1): 53-64.
  4. Liu, Y., Munoz, N., Bunnell, B. A., Logan, T. M. and Ma, T. (2015). Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells. Stem Cells 33(11): 3368-3381.
  5. Strong, A. L., Ohlstein, J. F., Biagas, B. A., Rhodes, L. V., Pei, D. T., Tucker, H. A., Llamas, C., Bowles, A. C., Dutreil, M. F., Zhang, S., Gimble, J. M., Burow, M. E. and Bunnell, B. A. (2015). Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers. Breast Cancer Res 17: 112.
  6. Strong, A. L., Bowles, A. C., MacCrimmon, C. P., Frazier, T. P., Lee, S. J., Wu, X., Katz, A. J., Gawronska-Kozak, B., Bunnell, B. A. and Gimble, J. M. (2015). Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair. Stem Cells Transl Med 4(6): 632-642.
  7. Scarritt, M. E., Pashos, N. C. and Bunnell, B. A. (2015). A review of cellularization strategies for tissue engineering of whole organs. Front Bioeng Biotechnol 3: 43.
  8. Strong, A. L., Bowles, A. C., MacCrimmon, C. P., Lee, S. J., Frazier, T. P., Katz, A. J., Gawronska-Kozak, B., Bunnell, B. A. and Gimble, J. M. (2015). Characterization of a Murine Pressure Ulcer Model to Assess Efficacy of Adipose-derived Stromal Cells. Plast Reconstr Surg Glob Open 3(3): e334.
  9. Tran, T. D., Yao, S., Hsu, W. H., Gimble, J. M., Bunnell, B. A. and Cheng, H. (2015). Arginine vasopressin inhibits adipogenesis in human adipose-derived stem cells. Mol Cell Endocrinol 406: 1-9.
  10. Strong, A. L., Gimble, J. M. and Bunnell, B. A. (2015). Analysis of the Pro- and Anti-Inflammatory Cytokines Secreted by Adult Stem Cells during Differentiation. Stem Cells Int 2015: 412467.
  11. Grayson, W. L., Bunnell, B. A., Martin, E., Frazier, T., Hung, B. P. and Gimble, J. M. (2015). Stromal cells and stem cells in clinical bone regeneration. Nat Rev Endocrinol 11(3): 140-150.
  12. Jackson, K. L., Dayton, R. D., Fisher-Perkins, J. M., Didier, P. J., Baker, K. C., Weimer, M., Gutierrez, A., Cain, C. D., Mathis, J. M., Gitcho, M. A., Bunnell, B. A. and Klein, R. L. (2015). Initial gene vector dosing for studying symptomatology of amyotrophic lateral sclerosis in non-human primates. J Med Primatol 44(2): 66-75.
  13. Strong, A. L., Burow, M. E., Gimble, J. M. and Bunnell, B. A. (2015). Concise review: The obesity cancer paradigm: exploration of the interactions and crosstalk with adipose stem cells. Stem Cells 33(2): 318-326.
  14. Strong, A. L., Shi, Z., Strong, M. J., Miller, D. F., Rusch, D. B., Buechlein, A. M., Flemington, E. K., McLachlan, J. A., Nephew, K. P., Burow, M. E. and Bunnell, B. A. (2015). Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells. Environ Health Perspect 123(1): 42-48.
  15. Strong, A. L., Ohlstein, J. F., Jiang, Q., Zhang, Q., Zheng, S., Boue, S. M., Elliott, S., Gimble, J. M., Burow, M. E., Wang, G. and Bunnell, B. A. (2014). Novel daidzein analogs enhance osteogenic activity of bone marrow-derived mesenchymal stem cells and adipose-derived stromal/stem cells through estrogen receptor dependent and independent mechanisms. Stem Cell Res Ther 5(4): 105.
  16. Espandar, L., Caldwell, D., Watson, R., Blanco-Mezquita, T., Zhang, S. and Bunnell, B. (2014). Application of adipose-derived stem cells on scleral contact lens carrier in an animal model of severe acute alkaline burn. Eye Contact Lens 40(4): 243-247.
  17. Strong, A. L., Gimble, J. M., Burow, M. E. and Bunnell, B. A. (2014). The effects of obesity on adipose-derived stromal cells and impact on breast cancer tumorigenesis. J. Cancer Biol. Res. 2:1031.
  18. Hong, S., Lu, Y., Tian, H., Alapure, B. V., Wang, Q., Bunnell, B. A. and Laborde, J. M. (2014). Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages. Chem Biol 21(10): 1318-1329.
  19. Ohlstein, J. F., Strong, A. L., McLachlan, J. A., Gimble, J. M., Burow, M. E. and Bunnell, B. A. (2014). Bisphenol A enhances adipogenic differentiation of human adipose stromal/stem cells. J Mol Endocrinol 53(3): 345-353.
  20. Ge, D., Zhang, Q. S., Zabaleta, J., Zhang, Q., Liu, S., Reiser, B., Bunnell, B. A., Braun, S. E., O'Brien, M. J., Savoie, F. H. and You, Z. (2014). Doublecortin may play a role in defining chondrocyte phenotype. Int J Mol Sci 15(4): 6941-6960.
  21. Zhang, S., Danchuk, S. D., Bonvillain, R. W., Xu, B., Scruggs, B. A., Strong, A. L., Semon, J. A., Gimble, J. M., Betancourt, A. M., Sullivan, D. E. and Bunnell, B. A. (2014). Interleukin 6 mediates the therapeutic effects of adipose-derived stromal/stem cells in lipopolysaccharide-induced acute lung injury. Stem Cells 32(6): 1616-1628.
  22. Strong, A. L., Jiang, Q., Zhang, Q., Zheng, S., Boue, S. M., Elliott, S., Burow, M. E., Bunnell, B. A. and Wang, G. (2014). Design, synthesis, and osteogenic activity of daidzein analogs on human mesenchymal stem cells. ACS Med Chem Lett 5(2): 143-148.
  23. Semon, J. A., Maness, C., Zhang, X., Sharkey, S. A., Beuttler, M. M., Shah, F. S., Pandey, A. C., Gimble, J. M., Zhang, S., Scruggs, B. A., Strong, A. L., Strong, T. A. and Bunnell, B. A. (2014). Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis. Stem Cell Res Ther 5(1): 2.
1 Protocol published
Isolation and Primary Culture of Adult Human Adipose-derived Stromal/Stem Cells
Authors:  Robert B. Jones, Amy L. Strong, Jeffrey M. Gimble and Bruce A. Bunnell, date: 03/05/2017, view: 1466, Q&A: 0
Adipose-derived stromal/stem cells (ASCs) are multipotent cells that can be isolated from adipose tissue. Studies have shown that cells have the capacity to self-renew and differentiate into adipocyte, chondrocyte, myocyte, and osteoblast lineages. ...