Julia Kraimer Biomedical Engineering, University of Cincinnati, USA
1 protocol

Tiffany Lee Radiological Health Engineering Program, Texas A & M University, USA
1 protocol

Wei Cai Materials Science and Engineering Program, University of California at San Diego
La Jolla, USA
1 protocol

Yu-Jui Chiu Materials Science and Engineering Program, University of California at San Diego
La Jolla, USA
1 protocol

Yu-Hwa Lo
  • Materials Science and Engineering Program, University of California at San Diego
La Jolla, USA
  • 1 Author merit


Ph.D in Electrcal Engineering and Computer Sciences, University of California, Berkeley, 1987

Current position

Professor in ECE Department (UC San Diego)
Director, San Diego Nanotechnology Infrastructure (SDNI)
Director, Nano3 (Nanoscience, Nanoengineering, Nanomedicine) Facility, California Institute for Telecommunications and Information Technology

Publications (since 2015)

  1. Wang, Y. W., Chen, T. Y., Yang, T. H., Chang, C. C., Yang, T. L., Lo, Y. H. and Huang, J. J. (2016). Thin-Film Transistor-Based Biosensors for Determining Stoichiometry of Biochemical Reactions. PLoS One 11(12): e0169094.
  2. Zhao, Y., Li, Q., Hu, X. and Lo, Y. (2016). Microfluidic cytometers with integrated on-chip optical systems for red blood cell and platelet counting. Biomicrofluidics 10(6): 064119.
  3. Zhang, T., Wei, T., Han, Y., Ma, H., Samieegohar, M., Chen, P. W., Lian, I. and Lo, Y. H. (2016). Protein-Ligand Interaction Detection with a Novel Method of Transient Induced Molecular Electronic Spectroscopy (TIMES): Experimental and Theoretical Studies. ACS Cent Sci 2(11): 834-842.
  4. Zhang, T., Ku, T. H., Han, Y., Subramanian, R., Niaz, I. A., Luo, H., Chang, D., Huang, J. J. and Lo, Y. H. (2016). Transient Induced Molecular Electronic Spectroscopy (TIMES) for study of protein-ligand interactions. Sci Rep 6: 35570.
  5. Ha, S., Khraiche, M. L., Akinin, A., Jing, Y., Damle, S., Kuang, Y., Bauchner, S., Lo, Y. H., Freeman, W. R., Silva, G. A. and Cauwenberghs, G. (2016). Towards high-resolution retinal prostheses with direct optical addressing and inductive telemetry. J Neural Eng 13(5): 056008.
  6. Chiu, Y. J., Cai, W., Shih, Y. R., Lian, I. and Lo, Y. H. (2016). A Single-Cell Assay for Time Lapse Studies of Exosome Secretion and Cell Behaviors. Small 12(27): 3658-3666.
  7. Zhang, A. C., Gu, Y., Han, Y., Mei, Z., Chiu, Y. J., Geng, L., Cho, S. H. and Lo, Y. H. (2016). Computational cell analysis for label-free detection of cell properties in a microfluidic laminar flow. Analyst 141(13): 4142-4150.
  8. Qiao, W., Wang, C., Ding, Z., Song, J. L., Wei, X. X. and Lo, Y. H. (2016). A two-stage electrophoretic microfluidic device for nucleic acid collection and enrichment. Microfluid Nanofluid 20: 77.
  9. Dai, J., Chiu, Y. J., Lian, I., Wu, T. F., Yang, K. and Lo, Y. H. (2016). A multi-channel clogging-resistant lab-on-a-chip cell counter and analyzer. J. Micromech. Microeng 26 025007.
  10. Aung, A., Bhullar, I. S., Theprungsirikul, J., Davey, S. K., Lim, H. L., Chiu, Y. J., Ma, X., Dewan, S., Lo, Y. H., McCulloch, A. and Varghese, S. (2016). 3D cardiac mutissues within a microfluidic device with real-time contractile stress readout. Lab Chip 16(1): 153-162.
  11. Hall, D., Liu, Y. H., and Lo, Y. H. (2015). Single photon avalanche detectors: prospects of new quenching and gain mechanisms. Nanophotonics 4(4): 397 - 412.
  12. Yen, T. M., Zhang, T., Chen, P. W., Ku, T. H., Chiu, Y. J., Lian, I. and Lo, Y. H. (2015). Self-Assembled Pico-Liter Droplet Microarray for Ultrasensitive Nucleic Acid Quantification. ACS Nano 9(11): 10655-10663.
  13. Hall, D., Li, B., Liu, Y. H., Yan, L. and Lo, Y. H. (2015). Complementary metal-oxide-semiconductor compatible 1060 nm photodetector with ultrahigh gain under low bias. Opt Lett 40(19): 4440-4443.
  14. Sullivan, C. J., Pendleton, E. D., Sasmor, H. H., Hicks, W. L., Farnum, J. B., Muto, M., Amendt, E. M., Schoborg, J. A., Martin, R. W., Clark, L. G., Anderson, M. J., Choudhury, A., Fior, R., Lo, Y. H., Griffey, R. H., Chappell, S. A., Jewett, M. C., Mauro, V. P. and Dresios, J. (2016). A cell-free expression and purification process for rapid production of protein biologics. Biotechnol J 11(2): 238-248.
  15. Han, Y. and Lo, Y-H. (2015). Imaging Cells in Flow Cytometer Using Spatial-Temporal Transformation. Sci Rep 5: 13267.
  16. Chiang, H. I., Chen, C. H. and Lo, Y. H. (2015). Integrated Lab-on-Chip System, Genome Sequencing of Single Microbial Cells, Project. In: Highlander, S. K., Rodriguez-Valera, F., White, B. A. (Eds). Encyclopedia of Metagenomics: Environmental Metagenomics. Springer, 285-290.
  17. Liu, Y. H., Yan, L., Zhang, A. C., D. H., Niaz, I. A., Zhou, Y., Sham, L. J., and Lo, Y. H. (2015). Cycling excitation process: An ultra efficient and quiet signal amplification mechanism in semiconductor. Appl. Phys. Lett. 107: 053505-1 – 053505-4.
  18. Ku, T. H., Zhang, T., Luo, H., Yen, T. M., Chen, P. W., Han, Y. and Lo, Y. H. (2015). Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing. Sensors (Basel) 15(7): 16281-16313.
  19. Wu, T. F., Qiao, W., Chiu, Y. J. and Lo, Y. H. (2015). Optofluidic lab-on-a-chip devices for photomedicine applications. Hamblin, M. R. and Avci, P. (Eds). Applications of Nanoscience in Photomedicine. Elsevier, 169-184.
  20. Zhou, Y., Liu, Y. H., Rahman, S. N., Hall, D., Sham, L. J. and Lo, Y. H. (2015). Discovery of a photoresponse amplification mechanism in compensated PN junctions. Appl Phys Lett 106(3): 031103-1 – 031103-5.
1 Protocol published
Quantitative Analysis of Exosome Secretion Rates of Single Cells
Authors:  Yu-Jui Chiu, Wei Cai, Tiffany Lee, Julia Kraimer and Yu-Hwa Lo, date: 02/20/2017, view: 1685, Q&A: 0
To study the inhomogeneity within a cell population including exosomes properties such as exosome secretion rate of cells and surface markers carried by exosomes, we need to quantify and characterize those exosomes secreted by each individual cell. ...