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Coauthors
Ruth Muschel CRUK-MRC Oxford Institute for Radiation Oncology, University of Oxford, UK
1 protocol

Jae Hong Im
  • CRUK-MRC Oxford Institute for Radiation Oncology, University of Oxford, UK
Contributions
  • 1 Author merit

Education

Ph.D in Chemical Engineering, Yonsei University, 1999

Current position

Senior Research Fellow, CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford

Publications (since 2010)

  1. Reymond, N., Im, J. H., Garg, R., Cox, S., Soyer, M., Riou, P., Colomba, A., Muschel, R. J. and Ridley, A. J. (2015). RhoC and ROCKs regulate cancer cell interactions with endothelial cells. Mol Oncol 9(6): 1043-1055.
  2. Im, J. H., Tapmeier, T., Balathasan, L., Gal, A., Yameen, S., Hill, S., Smart, S., Noterdaeme, O., Kelly, M., Brady, M., Fu, W., Kruse, K., Bernhard, E. J., Augustin, H. G. and Muschel, R. J. (2013). G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency. Int J Cancer 132(2): 315-326.
  3. Zhao, L., Lim, S. Y., Gordon-Weeks, A. N., Tapmeier, T. T., Im, J. H., Cao, Y., Beech, J., Allen, D., Smart, S. and Muschel, R. J. (2013). Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis. Hepatology 57(2): 829-839.
  4. Lim, S. Y., Gordon-Weeks, A. N., Zhao, L., Tapmeier, T. T., Im, J. H., Cao, Y., Beech, J., Allen, D., Smart, S. and Muschel, R. J. (2013). Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis. Oncoimmunology 2(3): e23187.
  5. Im, J. H. and Muschel, R. J. (2012). New evidence of lncRNA role in tumor progression and metastasis. Hepatobiliary Surg Nutr 1(1): 55-56.
  6. Reymond, N., Im, J. H., Garg, R., Vega, F. M., Borda d'Agua, B., Riou, P., Cox, S., Valderrama, F., Muschel, R. J. and Ridley, A. J. (2012). Cdc42 promotes transendothelial migration of cancer cells through beta1 integrin. J Cell Biol 199(4): 653-668.
  7. Gil-Bernabe, A. M., Ferjancic, S., Tlalka, M., Zhao, L., Allen, P. D., Im, J. H., Watson, K., Hill, S. A., Amirkhosravi, A., Francis, J. L., Pollard, J. W., Ruf, W. and Muschel, R. J. (2012). Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice. Blood 119(13): 3164-3175.
  8. Fokas, E., Im, J. H., Hill, S., Yameen, S., Stratford, M., Beech, J., Hackl, W., Maira, S. M., Bernhard, E. J., McKenna, W. G. and Muschel, R. J. (2012). Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vasculature. Cancer Res 72(1): 239-248.
  9. Qayum, N., Im, J., Stratford, M. R., Bernhard, E. J., McKenna, W. G. and Muschel, R. J. (2012). Modulation of the tumor microvasculature by phosphoinositide-3 kinase inhibition increases doxorubicin delivery in vivo. Clin Cancer Res 18(1): 161-169.
  10. Liu, S. K., Bham, S. A., Fokas, E., Beech, J., Im, J., Cho, S., Harris, A. L. and Muschel, R. J. (2011). Delta-like ligand 4-notch blockade and tumor radiation response. J Natl Cancer Inst 103(23): 1778-1798.
1 Protocol published
Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo
Authors:  Jae Hong Im and Ruth J. Muschel, date: 02/20/2017, view: 1832, Q&A: 0
Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...