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Coauthors
Nasreen Ehtesham Inflammation Biology and Cell Signaling Laboratory, National Institute of Pathology, India
1 protocol

Madhuri Suragani Department of Biochemistry, School of Life Sciences, University of Hyderabad, India
1 protocol

Manish Bhuwan Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, India
1 protocol

Seyed E. Hasnain
  • Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, India
Contributions
  • 1 Author merit

Education

Ph. D in Life Science, Jawaharlal Nehru University, Delhi, 1980

Current position

Vice Chancellor, Jamia Hamdard (Hamdard University), and Professor & Head, Jamia Hamdard-Institute of Molecular Medicine, Hamdard Nagar, New Delhi, India

Publications (since 2012)

  1. Grover, S., Gupta, P., Kahlon, P. S., Goyal, S., Grover, A., Dalal, K., Sabeeha, Ehtesham, N. Z. and Hasnain, S. E. (2016). Analyses of methyltransferases across the pathogenicity spectrum of different mycobacterial species point to an extremophile connection. Mol Biosyst 12(5): 1615-1625.
  2. Khubaib, M., Sheikh, J. A., Pandey, S., Srikanth, B., Bhuwan, M., Khan, N., Hasnain, S. E. and Ehtesham, N. Z. (2016). Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response. Front Microbiol 7: 719.
  3. Pandey, S., Sharma, A., Tripathi, D., Kumar, A., Khubaib, M., Bhuwan, M., Chaudhuri, T. K., Hasnain, S. E. and Ehtesham, N. Z. (2016). Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-Vivo. PLoS One 11(3): e0150288.
  4. Bhuwan, M., Arora, N., Sharma, A., Khubaib, M., Pandey, S., Chaudhuri, T. K., Hasnain, S. E. and Ehtesham, N. Z. (2016). Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System. MBio 7(2): e02259.
  5. Arish, M., Husein, A., Kashif, M., Sandhu, P., Hasnain, S. E., Akhter, Y. and Rub, A. (2015). Orchestration of membrane receptor signaling by membrane lipids. Biochimie 113: 111-124.
  6. Kohli, S., Singh, Y., Sowpati, D. T., Ehtesham, N. Z., Dobrindt, U., Hacker, J. and Hasnain, S. E. (2015). Human mesenchymal stem cells: New sojourn of bacterial pathogens. Int J Med Microbiol 305(3): 322-326.
  7. Hasnain, S. E., O'Toole, R. F., Grover, S. and Ehtesham, N. Z. (2015). Whole genome sequencing: a new paradigm in the surveillance and control of human tuberculosis. Tuberculosis (Edinb) 95(2): 91-94.
  8. Parsa, K. and Hasnain, S. E. (2015). Proteomics of multidrug resistant Mycobacterium tuberculosis clinical isolates: a peep show on mechanism of drug resistance & perhaps more. Indian J Med Res 141(1): 8-9.
  9. Kumar, N., Mariappan, V., Baddam, R., Lankapalli, A. K., Shaik, S., Goh, K. L., Loke, M. F., Perkins, T., Benghezal, M., Hasnain, S. E., Vadivelu, J., Marshall, B. J. and Ahmed, N. (2015). Comparative genomic analysis of Helicobacter pylori from Malaysia identifies three distinct lineages suggestive of differential evolution. Nucleic Acids Res 43(1): 324-335.
  10. Rahman, S. A., Singh, Y., Kohli, S., Ahmad, J., Ehtesham, N. Z., Tyagi, A. K. and Hasnain, S. E. (2014). Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis. MBio 5(6): e02020.
  11. Tundup, S., Mohareer, K. and Hasnain, S. E. (2014). Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation? FEBS Open Bio 4: 822-828.
  12. Singh, Y. and Hasnain, S. E. (2014). Holobionts: emerging strategy for interventions against infectious diseases, metabolic disorders & cancer. Indian J Med Res 140(1): 11-14.
  13. Singh, Y., Kohli, S., Sowpati, D. T., Rahman, S. A., Tyagi, A. K. and Hasnain, S. E. (2014). Gene cooption in mycobacteria and search for virulence attributes: comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria. Int J Med Microbiol 304(5-6): 742-748.
  14. Rani, P. S., Doddam, S. N., Agrawal, S., Hasnain, S. E., Sechi, L. A., Kumar, A. and Ahmed, N. (2014). Mycobacterium avium subsp. paratuberculosis is not discerned in diabetes mellitus patients in Hyderabad, India. Int J Med Microbiol 304(5-6): 620-625.
  15. Alamuru, N. P., Behera, S., Butchar, J. P., Tridandapani, S., Kaimal Suraj, S., Babu, P. P., Hasnain, S. E., Ehtesham, N. Z. and Parsa, K. V. (2014). A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages. J Leukoc Biol 95(5): 775-783.
  16. Kumar, A., Lewin, A., Rani, P. S., Qureshi, I. A., Devi, S., Majid, M., Kamal, E., Marek, S., Hasnain, S. E. and Ahmed, N. (2013). Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression. Cytokine 64(1): 25864.
  17. Singh, Y., Ahmad, J., Musarrat, J., Ehtesham, N. Z. and Hasnain, S. E. (2013). Emerging importance of holobionts in evolution and in probiotics. Gut Pathog 5(1): 12.
  18. Ahmad, J., Hasnain, S. E., Siddiqui, M. A., Ahamed, M., Musarrat, J. and Al-Khedhairy, A. A. (2013). MicroRNA in carcinogenesis & cancer diagnostics: a new paradigm. Indian J Med Res 137(4): 680-694.
  19. Mohareer, K., Sahdev, S. and Hasnain, S. E. (2013). Spodoptera frugiperda FKBP-46 is a consensus p53 motif binding protein. J Cell Biochem 114(4): 899-907.
  20. Saini, V., Raghuvanshi, S., Khurana, J. P., Ahmed, N., Hasnain, S. E., Tyagi, A. K. and Tyagi, A. K. (2012). Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution. Nucleic Acids Res 40(21): 10832-10850.
  21. Kohli, S., Singh, Y., Sharma, K., Mittal, A., Ehtesham, N. Z. and Hasnain, S. E. (2012). Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H37Rv and H37Ra reveal novel and interesting differences with implications in virulence. Nucleic Acids Res 2012 40(15):7113-22.
  22. Akhter, Y., Ehebauer, M. T., Mukhopadhyay, S. and Hasnain, S. E. (2012). The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more? Biochimie 94(1): 110-116.
1 Protocol published
Aggregation Prevention Assay for Chaperone Activity of Proteins Using Spectroflurometry
Authors:  Manish Bhuwan, Madhuri Suragani, Nasreen Z. Ehtesham and Seyed E. Hasnain, date: 01/20/2017, view: 2342, Q&A: 0
The ability to stabilize other proteins against thermal aggregation is one of the major characteristics of chaperone proteins. Molecular chaperones bind to nonnative conformations of proteins. Folding of the substrate is triggered by a dynamic ...