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Coauthors
Seyed Hasnain Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, India
1 protocol

Madhuri Suragani Department of Biochemistry, School of Life Sciences, University of Hyderabad, India
1 protocol

Manish Bhuwan Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, India
1 protocol

Nasreen Z. Ehtesham
  • Inflammation Biology and Cell Signaling Laboratory, National Institute of Pathology, India
  • 1 Author merit

Education

Ph.D in Human Genetics, National Institute of Immunology, Delhi, 1991

Current position

Scientist “G”, Director Grade Scientist, National Institute of Pathology, New Delhi, India

Publications (since 2012)

  1. Grover, S., Gupta, P., Kahlon, P. S., Goyal, S., Grover, A., Dalal, K., Sabeeha, Ehtesham, N. Z. and Hasnain, S. E. (2016). Analyses of methyltransferases across the pathogenicity spectrum of different mycobacterial species point to an extremophile connection. Mol Biosyst 12(5): 1615-1625.
  2. Khubaib, M., Sheikh, J. A., Pandey, S., Srikanth, B., Bhuwan, M., Khan, N., Hasnain, S. E. and Ehtesham, N. Z. (2016). Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response. Front Microbiol 7: 719.
  3. Pandey, S., Sharma, A., Tripathi, D., Kumar, A., Khubaib, M., Bhuwan, M., Chaudhuri, T. K., Hasnain, S. E. and Ehtesham, N. Z. (2016). Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-Vivo. PLoS One 11(3): e0150288.
  4. Bhuwan, M., Arora, N., Sharma, A., Khubaib, M., Pandey, S., Chaudhuri, T. K., Hasnain, S. E. and Ehtesham, N. Z. (2016). Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System. MBio 7(2): e02259.
  5. Rasheedi, S., Suragani, M., Raviprasad, P., Ghosh, S., Suragani, R. N., Ramaiah, K. V. and Ehtesham, N. Z. (2015). Functional characterization of PeIF5B as eIF5B homologue from Pisum sativum. Biochimie 118: 36-43.
  6. Kohli, S., Singh, Y., Sowpati, D. T., Ehtesham, N. Z., Dobrindt, U., Hacker, J. and Hasnain, S. E. (2015). Human mesenchymal stem cells: New sojourn of bacterial pathogens. Int J Med Microbiol 305(3): 322-326.
  7. Rahman, S. A., Singh, Y., Kohli, S., Ahmad, J., Ehtesham, N. Z., Tyagi, A. K. and Hasnain, S. E. (2015). Reply to '"Mycobacterium indicus pranii" is a strain of Mycobacterium intracellulare': "M. indicus pranii" is a distinct strain, not derived from M. intracellulare, and is an organism at an evolutionary transition point between a fast grower and slow grower. MBio 6(2).
  8. Singh, A., Suragani, M., Ehtesham, N. Z. and Krishna, A. (2015). Localization of resistin and its possible roles in the ovary of a vespertilionid bat, Scotophilus heathi. Steroids 95: 17-23.
  9. Hasnain, S. E., O'Toole, R. F., Grover, S. and Ehtesham, N. Z. (2015). Whole genome sequencing: a new paradigm in the surveillance and control of human tuberculosis. Tuberculosis (Edinb) 95(2): 91-94.
  10. Rahman, S. A., Singh, Y., Kohli, S., Ahmad, J., Ehtesham, N. Z., Tyagi, A. K. and Hasnain, S. E. (2014). Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis. MBio 5(6): e02020.
  11. Kolli, S. K., Prasad, B., Babu, P. V., Ashfaq, M. A., Ehtesham, N. Z., Raju, R. R. and Pal, M. (2014). TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells. Org Biomol Chem 12(32): 6080-6084.
  12. Alamuru, N. P., Behera, S., Butchar, J. P., Tridandapani, S., Kaimal Suraj, S., Babu, P. P., Hasnain, S. E., Ehtesham, N. Z. and Parsa, K. V. (2014). A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages. J Leukoc Biol 95(5): 775-783.
  13. Basak, S., Ehtesham, N. Z., Sesikeran, B. and Ghosh, S. (2014). Detection and identification of transgenic elements by fluorescent-PCR-based capillary gel electrophoresis in genetically modified cotton and soybean. J AOAC Int 97(1): 159-165.
  14. Suragani, M., Aadinarayana, V. D., Pinjari, A. B., Tanneeru, K., Guruprasad, L., Banerjee, S., Pandey, S., Chaudhuri, T. K. and Ehtesham, N. Z. (2013). Human resistin, a proinflammatory cytokine, shows chaperone-like activity. Proc Natl Acad Sci U S A 110(51): 20467-20472.
  15. Singh, Y., Ahmad, J., Musarrat, J., Ehtesham, N. Z. and Hasnain, S. E. (2013). Emerging importance of holobionts in evolution and in probiotics. Gut Pathog 5(1): 12.
  16. Tyagi, A., Kumar, U., Reddy, S., Santosh, V. S., Mohammed, S. B., Ehtesham, N. Z. and Ibrahim, A. (2012). Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with alpha-linolenic acid in a rat model of inflammatory bowel disease. Br J Nutr 108(9): 1612-1622.
  17. Kohli, S., Singh, Y., Sharma, K., Mittal, A., Ehtesham, N. Z. and Hasnain, S. E. (2012). Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H37Rv and H37Ra reveal novel and interesting differences with implications in virulence. Nucleic Acids Res 2012 40(15):7113-22.
1 Protocol published
Aggregation Prevention Assay for Chaperone Activity of Proteins Using Spectroflurometry
Authors:  Manish Bhuwan, Madhuri Suragani, Nasreen Z. Ehtesham and Seyed E. Hasnain, date: 01/20/2017, view: 2352, Q&A: 0
The ability to stabilize other proteins against thermal aggregation is one of the major characteristics of chaperone proteins. Molecular chaperones bind to nonnative conformations of proteins. Folding of the substrate is triggered by a dynamic ...