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Coauthors
Silke Meiners Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Germany
1 protocol

Hermen Overkleeft Department of Bio-organic Synthesis, Leiden University, The Netherlands
1 protocol

Bogdan Florea Department of Bio-organic Synthesis, Leiden University, The Netherlands
1 protocol

Oliver Vosyka Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Germany
1 protocol

Ilona E. Kammerl
  • Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Germany
Contributions
  • 1 Author merit

Education

Ph.D in Faculty of Medicine, Ludwig-Maximilians University, Munich

Current Position

Postdoctoral in Comprehensive Pneumology Center (CPC), Ludwig-Maximilians-University, Helmholtz Zentrum München, Munich

Publications

  1. Kammerl, I. E. and Meiners, S. (2016). Proteasome function shapes innate and adaptive immune responses. Am J Physiol Lung Cell Mol Physiol 311(2): L328-336.
  2. Kammerl, I. E., Dann, A., Mossina, A., Brech, D., Lukas, C., Vosyka, O., Nathan, P., Conlon, T. M., Wagner, D. E., Overkleeft, H. S., Prasse, A., Rosas, I. O., Straub, T., Krauss-Etschmann, S., Konigshoff, M., Preissler, G., Winter, H., Lindner, M., Hatz, R., Behr, J., Heinzelmann, K., Yildirim, A. O., Noessner, E., Eickelberg, O. and Meiners, S. (2016). Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 193(11): 1230-1241.
  3. Chen, S., Kammerl, I. E., Vosyka, O., Baumann, T., Yu, Y., Wu, Y., Irmler, M., Overkleeft, H. S., Beckers, J., Eickelberg, O., Meiners, S. and Stoeger, T. (2016). Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages. Cell Death Differ 23(6): 1026-1037.
  4. Semren, N., Welk, V., Korfei, M., Keller, I. E., Fernandez, I. E., Adler, H., Gunther, A., Eickelberg, O. and Meiners, S. (2015). Regulation of 26S Proteasome Activity in Pulmonary Fibrosis. Am J Respir Crit Care Med 192(9): 1089-1101.
  5. Keller, I. E., Vosyka, O., Takenaka, S., Kloss, A., Dahlmann, B., Willems, L. I., Verdoes, M., Overkleeft, H. S., Marcos, E., Adnot, S., Hauck, S. M., Ruppert, C., Gunther, A., Herold, S., Ohno, S., Adler, H., Eickelberg, O. and Meiners, S. (2015). Regulation of immunoproteasome function in the lung. Sci Rep 5: 10230.
  6. Meiners, S., Keller, I. E., Semren, N. and Caniard, A. (2014). Regulation of the proteasome: evaluating the lung proteasome as a new therapeutic target. Antioxid Redox Signal 21(17): 2364-2382.
  7. van Rijt, S. H., Keller, I. E., John, G., Kohse, K., Yildirim, A. O., Eickelberg, O. and Meiners, S. (2012). Acute cigarette smoke exposure impairs proteasome function in the lung. Am J Physiol Lung Cell Mol Physiol 303(9): L814-823.
  8. Wahler, A., Beyer, A. S., Keller, I. E., Schnack, C., von Einem, B., Propper, C., Boeckers, T. M., Peltan, I. D., Strickland, D. K., Hyman, B. T. and von Arnim, C. A. (2013). Engulfment adaptor phosphotyrosine-binding-domain-containing 1 (GULP1) is a nucleocytoplasmic shuttling protein and is transactivationally active together with low-density lipoprotein receptor-related protein 1 (LRP1). Biochem J 450(2): 333-343.
  9. Beyer, A. S., von Einem, B., Schwanzar, D., Keller, I. E., Hellrung, A., Thal, D. R., Ingelsson, M., Makarova, A., Deng, M., Chhabra, E. S., Propper, C., Bockers, T. M., Hyman, B. T. and von Arnim, C. A. (2012). Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-beta precursor protein. Neurobiol Aging 33(4): 732-743.
1 Protocol published
Activity-based Pull-down of Proteolytic Standard and Immunoproteasome Subunits
Activity-based probes (ABP) are small organic molecules that irreversibly bind to the active center of a specific enzyme family and may be coupled to a fluorophore or an affinity tag (Li et al., 2013). Here, we describe a method to ...