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Coauthors
Wonil Oh Biomedical Research Institute, R&D Center, MEDIPOST Co., Ltd., Republic of Korea
1 protocol

Soo Choi Biomedical Research Institute, R&D Center, MEDIPOST Co., Ltd., Republic of Korea
1 protocol

Miyoung Lee Biomedical Research Institute, R&D Center, MEDIPOST Co., Ltd., Republic of Korea
1 protocol

Sang Jeong Biomedical Research Institute, R&D Center, MEDIPOST Co., Ltd., Republic of Korea
1 protocol

Hong Bae Jeon
  • Biomedical Research Institute, R&D Center, MEDIPOST Co., Ltd., Republic of Korea
Contributions
  • 1 Author merit

Education

Ph.D in Protein Biochemistry, Department of Life Science, Gwangju Institute of Science and Technology (GIST), 2007

Current Position

Research Division Leader, Biomedical Research Institute, R&D center, MEDIPOST Co., Ltd., Seoul, Korea 

Publications

  1. You, S. Y., Park, Y. S., Jeon, H. J., Cho, D. H., Jeon, H. B., Kim, S. H., Chang, J. W., Kim, J. S. and Oh, J. S. (2016). Beclin-1 knockdown shows abscission failure but not autophagy defect during oocyte meiotic maturation. Cell Cycle 15(12): 1611-1619.
  2. Jin, H. J., Kwon, J. H., Kim, M., Bae, Y. K., Choi, S. J., Oh, W., Yang, Y. S. and Jeon, H. B. (2016). Downregulation of Melanoma Cell Adhesion Molecule (MCAM/CD146) Accelerates Cellular Senescence in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells. Stem Cells Transl Med 5(4): 427-439.
  3. Jeong, S. Y., Ha, J., Lee, M., Jin, H. J., Kim, D. H., Choi, S. J., Oh, W., Yang, Y. S., Kim, J. S., Kim, B. G., Chang, J. H., Cho, D. H. and Jeon, H. B. (2015). Autocrine Action of Thrombospondin-2 Determines the Chondrogenic Differentiation Potential and Suppresses Hypertrophic Maturation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells. Stem Cells 33(11): 3291-3303.
  4. Kim, E. S., Jeon, H. B., Lim, H., Shin, J. H., Park, S. J., Jo, Y. K., Oh, W., Yang, Y. S., Cho, D. H. and Kim, J. Y. (2015). Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF. PLoS One 10(5): e0128078.
  5. Choe, M. H., Min, J. W., Jeon, H. B., Cho, D. H., Oh, J. S., Lee, H. G., Hwang, S. G., An, S., Han, Y. H. and Kim, J. S. (2015). ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer. Oncotarget 6(5): 2654-2666.
  6. Lee, N., Kim, I., Park, S., Han, D., Ha, S., Kwon, M., Kim, J., Byun, S. H., Oh, W., Jeon, H. B., Kweon, D. H., Cho, J. Y. and Yoon, K. (2015). Creatine inhibits adipogenesis by downregulating insulin-induced activation of the phosphatidylinositol 3-kinase signaling pathway. Stem Cells Dev 24(8): 983-994.
  7. Kim, E. S., Park, S. J., Goh, M. J., Na, Y. J., Jo, D. S., Jo, Y. K., Shin, J. H., Choi, E. S., Lee, H. K., Kim, J. Y., Jeon, H. B., Kim, J. C. and Cho, D. H. (2014). Mitochondrial dynamics regulate melanogenesis through proteasomal degradation of MITF via ROS-ERK activation. Pigment Cell Melanoma Res 27(6): 1051-1062.
  8. Chang, Y. S., Ahn, S. Y., Jeon, H. B., Sung, D. K., Kim, E. S., Sung, S. I., Yoo, H. S., Choi, S. J., Oh, W. I. and Park, W. S. (2014). Critical role of vascular endothelial growth factor secreted by mesenchymal stem cells in hyperoxic lung injury. Am J Respir Cell Mol Biol 51(3): 391-399.
  9. Lee, M., Jeong, S. Y., Ha, J., Kim, M., Jin, H. J., Kwon, S. J., Chang, J. W., Choi, S. J., Oh, W., Yang, Y. S., Kim, J. S. and Jeon, H. B. (2014). Low immunogenicity of allogeneic human umbilical cord blood-derived mesenchymal stem cells in vitro and in vivo. Biochem Biophys Res Commun 446(4): 983-989.
  10. Min, J. W., Kim, K. I., Kim, H. A., Kim, E. K., Noh, W. C., Jeon, H. B., Cho, D. H., Oh, J. S., Park, I. C., Hwang, S. G. and Kim, J. S. (2013). INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells. Biochem Biophys Res Commun 440(1): 137-142.
  11. Jin, H. J., Bae, Y. K., Kim, M., Kwon, S. J., Jeon, H. B., Choi, S. J., Kim, S. W., Yang, Y. S., Oh, W. and Chang, J. W. (2013). Comparative analysis of human mesenchymal stem cells from bone marrow, adipose tissue, and umbilical cord blood as sources of cell therapy. Int J Mol Sci 14(9): 17986-18001.
  12. Jeong, S. Y., Kim, D. H., Ha, J., Jin, H. J., Kwon, S. J., Chang, J. W., Choi, S. J., Oh, W., Yang, Y. S., Kim, G., Kim, J. S., Yoon, J. R., Cho, D. H. and Jeon, H. B. (2013). Thrombospondin-2 secreted by human umbilical cord blood-derived mesenchymal stem cells promotes chondrogenic differentiation. Stem Cells 31(10): 2136-2148.
  13. Lee, E. J., Park, S. J., Kang, S. K., Kim, G. H., Kang, H. J., Lee, S. W., Jeon, H. B. and Kim, H. S. (2012). Spherical bullet formation via E-cadherin promotes therapeutic potency of mesenchymal stem cells derived from human umbilical cord blood for myocardial infarction. Mol Ther 20(7): 1424-1433.
  14. Kim, J. Y., Kim, D. H., Kim, J. H., Lee, D., Jeon, H. B., Kwon, S. J., Kim, S. M., Yoo, Y. J., Lee, E. H., Choi, S. J., Seo, S. W., Lee, J. I., Na, D. L., Yang, Y. S., Oh, W. and Chang, J. W. (2012). Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-beta plaques. Cell Death Differ 19(4): 680-691.
  15. Kim, S. M., Kim, D. S., Jeong, C. H., Kim, D. H., Kim, J. H., Jeon, H. B., Kwon, S. J., Jeun, S. S., Yang, Y. S., Oh, W. and Chang, J. W. (2011). CXC chemokine receptor 1 enhances the ability of human umbilical cord blood-derived mesenchymal stem cells to migrate toward gliomas. Biochem Biophys Res Commun 407(4): 741-746.
  16. Kim, J. Y., Kim, D. H., Kim, J. H., Yang, Y. S., Oh, W., Lee, E. H. and Chang, J. W. (2012). Umbilical cord blood mesenchymal stem cells protect amyloid-beta42 neurotoxicity via paracrine. World J Stem Cells 4(11): 110-116.
  17. Kim, J. Y., Jeon, H. B., Yang, Y. S., Oh, W. and Chang, J. W. (2010). Application of human umbilical cord blood-derived mesenchymal stem cells in disease models. World J Stem Cells 2(2): 34-38.
  18. Jeon, H. B., Choi, E. S., Yoon, J. H., Hwang, J. H., Chang, J. W., Lee, E. K., Choi, H. W., Park, Z. Y. and Yoo, Y. J. (2007). A proteomics approach to identify the ubiquitinated proteins in mouse heart. Biochem Biophys Res Commun 357(3): 731-736.
  19. Hwang, S. G., Yu, S. S., Ryu, J. H., Jeon, H. B., Yoo, Y. J., Eom, S. H. and Chun, J. S. (2005). Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin. J Biol Chem 280(13): 12758-12765.
  20. Cho, Y. R., Lee, S. J., Jeon, H. B., Park, Z. Y., Chun, J. S. and Yoo, Y. J. (2004). Under-sulfation by PAPS synthetase inhibition modulates the expression of ECM molecules during chondrogenesis. Biochem Biophys Res Commun 323(3): 769-775.
  21. Lee, S. J., Jeon, H. B., Lee, J. H., Yoo, J. S., Chun, J. S. and Yoo, Y. J. (2004). Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells. FEBS Lett 563(1-3): 35-40.
  22. Choi, W., Yoo, Y. J., Kim, M., Shin, D., Jeon, H. B. and Choi, W. (2003). Identification of proteins highly expressed in the hyphae of Candida albicans by two-dimensional electrophoresis. Yeast 20(12): 1053-1060.
  23. Chang, J. W., Jeon, H. B., Lee, J. H., Yoo, J. S., Chun, J. S., Kim, J. H. and Yoo, Y. J. (2001). Augmented expression of peroxiredoxin I in lung cancer. Biochem Biophys Res Commun 289(2): 507-512.
1 Protocol published
In vitro Chondrogenic Hypertrophy Induction of Mesenchymal Stem Cells
Authors:  Sang Young Jeong, Miyoung Lee, Soo Jin Choi, Wonil Oh and Hong Bae Jeon, date: 12/05/2016, view: 1933, Q&A: 0
To investigate underlying mechanism of chondrogenic hypertrophy, we need proper in vitro hypertrophic model of mesenchymal stem cells (MSCs). This protocol describes our defined method for induction of in vitro chondrogenic ...