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Coauthors
Guillermo Gomez University of South Australia
3 protocols

Xuan Liang Divisions of Cell Biology and Molecular Medicine, Institute for Molecular Bioscience, The University of Queensland, Australia
2 protocols

Magdalene Michael
  • Randall Division of Cell and Molecular Biophysics, King’s College London, Guy’s Campus, UK
Contributions
  • 2 Author merit

Education

Ph.D in Biomedical Sciences, Randall Division, King’s College London, 2009

Current Position

Postdoctoral Research Fellow, Randall Division, King’s College London, UK

Publications

  1. Priya, R., Wee, K., Budnar, S., Gomez, G. A., Yap, A. S. and Michael, M. (2016). Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle 15(22): 3033-3041.
  2. Michael, M., Meiring, J. C., Acharya, B. R., Matthews, D. R., Verma, S., Han, S. P., Hill, M. M., Parton, R. G., Gomez, G. A. and Yap, A. S. (2016). Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions. Dev Cell 37(1): 58-71.
  3. Lee, N. K., Fok, K. W., White, A., Wilson, N. H., O'Leary, C. J., Cox, H. L., Michael, M., Yap, A. S. and Cooper, H. M. (2016). Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun 7: 11082.
  4. Yap, A. S., Michael, M. and Parton, R. G. (2015). Seeing and believing: recent advances in imaging cell-cell interactions. F1000Res 4(F1000 Faculty Rev): 273.
  5. Moore, T., Wu, S. K., Michael, M., Yap, A. S., Gomez, G. A. and Neufeld, Z. (2014). Self-organizing actomyosin patterns on the cell cortex at epithelial cell-cell junctions. Biophys J 107(11): 2652-2661.
  6. Michael, M., Begum, R., Fong, K., Pourreyron, C., South, A. P., McGrath, J. A. and Parsons, M. (2014). BPAG1-e restricts keratinocyte migration through control of adhesion stability. J Invest Dermatol 134(3): 773-782.
  7. Han, S. P., Gambin, Y., Gomez, G. A., Verma, S., Giles, N., Michael, M., Wu, S. K., Guo, Z., Johnston, W., Sierecki, E., Parton, R. G., Alexandrov, K. and Yap, A. S. (2014). Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. J Biol Chem 289(11): 7764-7775.
  8. Wu, S. K., Gomez, G. A., Michael, M., Verma, S., Cox, H. L., Lefevre, J. G., Parton, R. G., Hamilton, N. A., Neufeld, Z. and Yap, A. S. (2014). Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia. Nat Cell Biol 16(2):167-178.
  9. Law, A. L., Vehlow, A., Kotini, M., Dodgson, L., Soong, D., Theveneau, E., Bodo, C., Taylor, E., Navarro, C., Perera, U., Michael, M., Dunn, G. A., Bennett, D., Mayor, R. and Krause, M. (2013). Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo. J Cell Biol 203(4): 673-689.
  10. Michael, M. and Yap, A. S. (2013). The regulation and functional impact of actin assembly at cadherin cell-cell adhesions. Semin Cell Dev Biol 24(4): 298-307.
  11. Verma, S., Han, S. P., Michael, M., Gomez, G. A., Yang, Z., Teasdale, R. D., Ratheesh, A., Kovacs, E. M., Ali, R. G. and Yap, A. S. (2012). A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Mol Biol Cell 23(23): 4601-4610.
  12. Liu, L., Dopping-Hepenstal, P. J., Lovell, P. A., Michael, M., Horn, H., Fong, K., Lai-Cheong, J. E., Mellerio, J. E., Parsons, M. and McGrath, J. A. (2012). Autosomal recessive epidermolysis bullosa simplex due to loss of BPAG1-e expression. J Invest Dermatol 132(3 Pt 1): 742-744.
  13. Michael, M., Vehlow, A., Navarro, C. and Krause, M. (2010). c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis. Curr Biol 20(9): 783-791.
  14. Lyulcheva, E., Taylor, E., Michael, M., Vehlow, A., Tan, S., Fletcher, A., Krause, M. and Bennett, D. (2008). Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferation. Dev Cell 15(5): 680-690.
2 Protocols published
Measurement of Mechanical Tension at cell-cell junctions using two-photon laser ablation
Authors:  Xuan Liang, Magdalene Michael and Guillermo A. Gomez, date: 12/20/2016, view: 1973, Q&A: 0
The cortical actomyosin cytoskeleton is found in all non-muscle cells where a key function is to control mechanical force (Salbreux et al., 2012). When coupled to E-cadherin cell-cell adhesion, cortical actomyosin generates junctional ...
Analysis of Myosin II Minifilament Orientation at Epithelial Zonula Adherens
Authors:  Magdalene Michael, Xuan Liang and Guillermo A. Gomez, date: 12/05/2016, view: 1819, Q&A: 0
Non-muscle myosin II (NMII) form bipolar filaments, which bind F-actin to exert cellular contractility during physiological processes (Vicente-Manzanares et al., 2009). Using a combinatorial approach to fluorescently label both N- and ...