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Coauthors
Juha Klefström Cancer Cell Circuitry Laboratory, Research Programs Unit/Translational Cancer Biology, University of Helsinki, Finland
2 protocols

Elsa Marques
  • Cancer Cell Circuitry Laboratory, Research Programs Unit/Translational Cancer Biology, University of Helsinki, Finland
Contributions
  • 1 Author merit

Education

Master of Science in Cellular and Molecular Biology by the Center of Neurosciences Coimbra & Faculty of Science and Technology, University of Coimbra, Portugal

Current Position

PhD student in Cancer Cell Circuitry Laboratory, Translational Cancer Biology Research Program of the Medical Faculty, University of Helsinki

Publications

  1. Haikala, H. M., Marques, E., Turunen, M. and Klefstrom, J. (2016). Myc requires RhoA/SRF to reprogram glutamine metabolism. Small GTPases: 1-9.
  2. Tervonen, T. A., Belitskin, D., Pant, S. M., Englund, J. I., Marques, E., Ala-Hongisto, H., Nevalaita, L., Sihto, H., Heikkila, P., Leidenius, M., Hewitson, K., Ramachandra, M., Moilanen, A., Joensuu, H., Kovanen, P. E., Poso, A. and Klefstrom, J. (2016). Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene 35(14): 1832-1846.
  3. Marques, E., Englund, J. I., Tervonen, T. A., Virkunen, E., Laakso, M., Myllynen, M., Makela, A., Ahvenainen, M., Lepikhova, T., Monni, O., Hautaniemi, S. and Klefstrom, J. (2016). Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers. Oncogene 35(11): 1386-1398.
  4. Marques, E. and Klefstrom, J. (2015). Par6 family proteins in cancer. Oncoscience 2(11): 894-895.
  5. Werner, S., Brors, B., Eick, J., Marques, E., Pogenberg, V., Parret, A., Kemming, D., Wood, A. W., Edgren, H., Neubauer, H., Streichert, T., Riethdorf, S., Bedi, U., Baccelli, I., Jucker, M., Eils, R., Fehm, T., Trumpp, A., Johnsen, S. A., Klefstrom, J., Wilmanns, M., Muller, V., Pantel, K. and Wikman, H. (2015). Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2. Cancer Discov 5(5): 506-519.
  6. Fontes-Ribeiro, C. A., Marques, E., Pereira, F. C., Silva, A. P. and Macedo, T. R. (2011). May exercise prevent addiction? Curr Neuropharmacol 9(1): 45-48.
  7. Tervonen, T. A., Partanen, J. I., Saarikoski, S. T., Myllynen, M., Marques, E., Paasonen, K., Moilanen, A., Wohlfahrt, G., Kovanen, P. E. and Klefstrom, J. (2011). Faulty epithelial polarity genes and cancer. Adv Cancer Res 111: 97-161.
  8. Pereira, F. C., Rolo, M. R., Marques, E., Mendes, V. M., Ribeiro, C. F., Ali, S. F., Morgadinho, T. and Macedo, T. R. (2008). Acute increase of the glutamate-glutamine cycling in discrete brain areas after administration of a single dose of amphetamine. Ann N Y Acad Sci 1139: 212-221.
  9. Simoes, P. F., Silva, A. P., Pereira, F. C., Marques, E., Milhazes, N., Borges, F., Ribeiro, C. F. and Macedo, T. R. (2008). Methamphetamine changes NMDA and AMPA glutamate receptor subunit levels in the rat striatum and frontal cortex. Ann N Y Acad Sci 1139: 232-241.
  10. Marques, E., Vasconcelos, F., Rolo, M. R., Pereira, F. C., Silva, A. P., Macedo, T. R. and Ribeiro, C. F. (2008). Influence of chronic exercise on the amphetamine-induced dopamine release and neurodegeneration in the striatum of the rat. Ann N Y Acad Sci 1139: 222-231.
  11. Simoes, P. F., Silva, A. P., Pereira, F. C., Marques, E., Grade, S., Milhazes, N., Borges, F., Ribeiro, C. F. and Macedo, T. R. (2007). Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory. Neuroscience 150(2): 433-441.
1 Protocol published
Lentiviral shRNA Screen to Identify Epithelial Integrity Regulating Genes in MCF10A 3D Culture
Authors:  Elsa Marques and Juha Klefström, date: 12/05/2016, view: 2019, Q&A: 0
MCF10A 3D culture system provides a reductionist model of glandular mammary epithelium which is widely used to study development of glandular architecture, the role of cell polarity and epithelial integrity in control of epithelial cell functions, ...