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Coauthors
Clifford Lowell Department of Laboratory Medicine and the Program in Immunology, University of California, USA
1 protocol
Coreviewers
Andrea Puhar The Laboratory for Molecular Infection Medicine Sweden (MIMS) and Department of Molecular Biology, Umea University, Sweden
13 protocols

Benoit Chassaing Clermont Université, Université d'Auvergne, M2iSH, UMR 1071 INSERM, UNC 2018 INRA, France
11 protocols

Emilie Besnard Buck Institute for Research on Aging
6 protocols

Fanglian He Department of Biology, University of Pennsylvania, USA
205 protocols

Meenal Sinha
  • Department of Laboratory Medicine and the Program in Immunology, University of California, USA
Research focus
  • Immunology
Contributions
  • 1 Author merit
  • 14 Reviewer merit

Education

Ph.D in Immunology, University of Texas at Houston, 2008

Current Position

Associate Specialist, University of California, San Francisco, USA

Publications

  1. Chen, J., Zhong, M. C., Guo, H., Davidson, D., Mishel, S., Lu, Y., Rhee, I., Perez-Quintero, L. A., Zhang, S., Cruz-Munoz, M. E., Wu, N., Vinh, D. C., Sinha, M., Lowell, C. A., Danska, J. S. and Veillette, A. (2017). SLAMF7 is critical receptor for phagocytosis of hematopoietic tumor cells via Mac-1 integrin-dependent mechanism. Nature.

  2. Lee, L. M., Ji, M., Sinha, M., Dong, M. B., Ren, X., Wang, Y., Lowell, C. A., Ghosh, S., Locksley, R. M. and DeFranco, A. L. (2016). Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9. PLoS One 11(12): e0167693.

  3. Wang, H., Li, M., Hung, C. Y., Sinha, M., Lee, L. M., Wiesner, D. L., LeBert, V., Lerksuthirat, T., Galles, K., Suresh, M., DeFranco, A. L., Lowell, C. A., Klein, B. S. and Wuthrich, M. (2016). MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. PLoS Pathog 12(8): e1005787.

  4. Sinha, M. and Lowell, C. A. (2016). Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells. Am J Respir Cell Mol Biol 54(6): 802-813.
  5. Kerr, S. C., Fischer, G. J., Sinha, M., McCabe, O., Palmer, J. M., Choera, T., Lim, F. Y., Wimmerova, M., Carrington, S. D., Yuan, S., Lowell, C. A., Oscarson, S., Keller, N. P. and Fahy, J. V. (2016). FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. PLoS Pathog 12(4): e1005555.
  6. Deguine, J., Sinha, M., Lowell, C. A. and Barton, G. (2015). Regulation of neutrophil cytokine production during inflammation. J Immunol 194(1 Supplement): 192.21.
  7. Sinha, M., Drouin, S. M., Woodruff, T., Taylor, S. and Wetsel, R. A. (2008). The Receptor for Complement Anaphylatoxin C5a Protects Against the Development of Airway Hyperresponsiveness in Allergic Asthma by Inhibiting Cysteinyl Leukotriene Pathway. Mol Immunol 45: 4109-4110.
  8. Sinha, M., Drouin, S. M. and Wetsel, R. A. (2008). The Receptor for Complement Anaphylatoxin C5a Protects Against the Development of Airway Hyperresponsiveness in Allergic Asthma by Inhibiting Cysteinyl Leukotriene Pathway. FASEB J 22(1 Supplement): 574.2.
  9. Dillard, P., Wetsel, R. A. and Drouin, S. M. (2007). Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses. Am J Respir Crit Care Med 175(12): 1250-1258.
  10. Connelly, M. A., Moulton, R. A., Smith, A. K., Lindsey, D. R., Sinha, M., Wetsel, R. A. and Jagannath, C. (2007). Mycobacteria-primed macrophages and dendritic cells induce an up-regulation of complement C5a anaphylatoxin receptor (CD88) in CD3+ murine T cells. J Leukoc Biol 81(1): 212-220.
  11. Drouin, S. M., Sinha, M., Sfyroera, G., Lambris, J. D. and Wetsel, R. A. (2006). A protective role for the fifth complement component (c5) in allergic airway disease. Am J Respir Crit Care Med 173(8): 852-857.
  12. Planque, S., Zhou, Y. X., Nishiyama, Y., Sinha, M., O'Connor-Mccourt, M., Arnett, F. C. and Paul, S. (2003). Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice. FASEB J 17(2): 136-143.
  13. Sinha, M. and Molldrem, J. J. (2002). A Single Nucleotide Polymorphism in Proteinase 3 That Codes for HLA-A2-Binding Peptides Protects Against Development of Acute Myelogenous Leukemia. Blood 100(11): Abstract No 2194.
1 Protocol published
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting
Authors:  Meenal Sinha and Clifford A. Lowell, date: 11/20/2016, view: 2714, Q&A: 0
In this protocol, we describe the method for isolating highly pure primary alveolar epithelial type II (ATII) cells from lungs of naïve mice. The method combines negative selection for a variety of lineage markers along with positive selection for ...
14 Protocols reviewed
Detection of ASC Oligomerization by Western Blotting
Authors:  Jérôme Lugrin and Fabio Martinon , date: 05/20/2017, view: 899, Q&A: 0
The apoptosis-associated speck-like protein with a caspase-recruitment domain (ASC) adaptor protein bridges inflammasome sensors and caspase-1. Upon inflammasome activation, ASC nucleates in a prion-like manner into a large and single platform ...
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Mouse CD8+ T Cell Migration in vitro and CXCR3 Internalization Assays
Authors:  Rosa Barreira da Silva and Matthew L. Albert, date: 03/20/2017, view: 1030, Q&A: 0
Chemokines are molecules that regulate the positioning of cells during homeostasis and inflammation. CXCL10 is an interferon-induced chemokine that attracts cells that express the chemokine receptor CXCR3 on their surface. CXCL10 expression is often ...
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