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Coauthors
Hui Zheng Huffington Center on Aging, Baylor College of Medicine, USA
2 protocols

Ethan Roy Huffington Center on Aging, Baylor College of Medicine, USA
2 protocols

Hong Lian
  • Institute of Neuroscience, Zhejiang University School of Medicine, China
Contributions
  • 2 Author merit

Education

Ph.D., Department of Molecular and Human Genetics, Huffington Center on Aging, 2014

Current position

Associate professor, Department of Basic Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

Publications

  1. Lian, H. and Zheng, H. (2016). Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease. J Neurochem 136(3): 475-491.

  2. Lian, H., Litvinchuk, A., Chang, A., Aithmitti, N., Jankowsky, J. L. and Zheng, H. (2016). Astrocyte-Microglia Crosstalk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease. Journal of Neuroscience 36(2):577-589.

  3. Lian, H., Yang, L., Cole, A., Sun, L., Chiang, A. C., Fowler, S. W., Shim, D. J., Rodriguez-Rivera, J., Taglialatela, G., Jankowsky, J. L., Lu, H. C. and Zheng, H. (2015). NFkappaB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease. Neuron 85(1): 101-115.

  4. Lian, H., Shim, D. J., Gaddam, S. S., Rodriguez-Rivera, J., Bitner, B. R., Pautler, R. G., Robertson, C. S. and Zheng, H. (2012). IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: Implications for functional recovery. Molecular Neurodegeneration 7:47.

  5. Lian, H., Yu, J. Q., Ge, Y. F. and Fang, S. G. (2009). Nine novel microsatellite markers for the hog deer (Axis porcinus). Conservation Genetics 10(3):681-683.

2 Protocols published
Protocol for Primary Microglial Culture Preparation
Authors:  Hong Lian, Ethan Roy and Hui Zheng, date: 11/05/2016, view: 3097, Q&A: 0
Primary microglia, in either mono-culture or co-culture with neurons or astrocytes, are a powerful tool for studying mechanisms underlying microglial inflammatory responses and cell type-specific interactions in the central nervous system (CNS). ...
Microglial Phagocytosis Assay
Authors:  Hong Lian, Ethan Roy and Hui Zheng, date: 11/05/2016, view: 3021, Q&A: 0
Phagocytosis is essential for microglial clearance of apoptotic cells, extracellular protein aggregates, and infectious bacteria in the central nervous system (CNS). While the preparation of primary microglial culture has been described elsewhere, ...