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Coauthors
Michael Hebeisen Department of Oncology, Lausanne University Hospital Center (CHUV) and University of Lausanne, Switzerland
1 protocol

Nathalie Rufer Department of Oncology, Lausanne University Hospital Center (CHUV) and University of Lausanne, Switzerland
1 protocol

Pedro Romero Ludwig Center for Cancer Research (LICR), Lausanne Branch, Switzerland
3 protocols

Daniel Speiser Ludwig Center for Cancer Research (LICR), Lausanne Branch, Switzerland
1 protocol

Petra Baumgaertner
  • Ludwig Center for Cancer Research (LICR), Lausanne Branch, Switzerland
  • 1 Author merit

Education

PhD in Biochemistry at the JW Goethe University, Frankfurt, Germany, 1998

Publications

  1. Hebeisen, M., Schmidt, J., Guillaume, P., Baumgaertner, P., Speiser, D. E., Luescher, I. and Rufer, N. (2015). Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells. Cancer Res 75(10): 1983-1991.

  2. Meyer, C., Cagnon, L., Costa-Nunes, C. M., Baumgaertner, P., Montandon, N., Leyvraz, L., Michielin, O., Romano, E. and Speiser, D. E. (2014). Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab. Cancer Immunol Immunother 63(3): 247-257.

  3. Mahnke, Y. D., Devevre, E., Baumgaertner, P., Matter, M., Rufer, N., Romero, P. and Speiser, D. E. (2012). Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo. Oncoimmunology 1(4): 467-530.

  4. Lovgren, T., Baumgaertner, P., Wieckowski, S., Devevre, E., Guillaume, P., Luescher, I., Rufer, N. and Speiser, D. E. (2012). Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose. Cancer Immunol Immunother 61(6): 817-826.

  5. Baumgaertner, P., Jandus, C., Rivals, J. P., Derre, L., Lovgren, T., Baitsch, L., Guillaume, P., Luescher, I. F., Berthod, G., Matter, M., Rufer, N., Michielin, O. and Speiser, D. E. (2012). Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. Int J Cancer 130(11): 2607-2617.

  6. Speiser, D. E., Wieckowski, S., Gupta, B., Iancu, E. M., Baumgaertner, P., Baitsch, L., Michielin, O., Romero, P. and Rufer, N. (2011). Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes. Proc Natl Acad Sci U S A 108(37): 15318-15323.

  7. Speiser, D. E., Baumgaertner, P., Voelter, V., Devevre, E., Barbey, C., Rufer, N. and Romero, P. (2008). Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proc Natl Acad Sci U S A 105(10): 3849-3854.

1 Protocol published
Chromium-51 (51Cr) Release Assay to Assess Human T Cells for Functional Avidity and Tumor Cell Recognition
Authors:  Petra Baumgaertner, Daniel E. Speiser, Pedro Romero, Nathalie Rufer and Michael Hebeisen, date: 08/20/2016, view: 2691, Q&A: 0
Cytotoxic CD8+ T cells are able to specifically recognize and kill target cells through specific interaction between their T cell receptors (TCRs) and small immunogenic peptides (antigens) presented by major histocompatibility complex ...