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Coauthors
Ian Ganley MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, UK
2 protocols

Michael J. Munson
  • MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, UK
Contributions
  • 2 Author merit

Education

Ph.D. in Microbiology, University of Dundee, 2014

Current position

Post-doctoral researcher at the University of Oslo, Department of Molecular Medicine, Division of Biochemistry

Publications

  1. Munson, M. J., Allen, G. F., Toth, R., Campbell, D. G., Lucocq, J. M. and Ganley, I. G. (2015). mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J 34(17): 2272-2290.

  2. Munson, M. J. and Ganley, I. G. (2015). MTOR, PIK3C3, and autophagy: Signaling the beginning from the end. Autophagy 11(12): 2375-2376.

  3. Stretton, C., Hoffmann, T. M., Munson, M. J., Prescott, A., Taylor, P. M., Ganley, I. G. and Hundal, H. S. (2015). GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling. Biochem J 470(2): 207-221.

  4. Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. and Alessi, D. R. (2014). Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. Biochem J 463(3): 413-427.

2 Protocols published
Determination of VPS34/PIK3C3 Activity in vitro Utilising 32P-γATP
Authors:  Michael J. Munson and Ian G. Ganley, date: 08/20/2016, view: 2295, Q&A: 0
VPS34 is the only class III phosphatidylinositol-3-kinase (PI3K) in mammalian cells and produces the vast majority of cellular phosphatidylinositol-3-phosphate [PI(3)P]. PI(3)P is a key signalling lipid that plays many membrane trafficking roles in ...
Determination of Cellular Phosphatidylinositol-3-phosphate (PI3P) Levels Using a Fluorescently Labelled Selective PI3P Binding Domain (PX)
Authors:  Michael J. Munson and Ian G. Ganley, date: 08/20/2016, view: 1924, Q&A: 0
The lipid Phosphatidylinositol-3-phosphate [PtdIns3P or PI(3)P] plays many membrane trafficking roles and is primarily produced by the Class III PI3K, VPS34. Determining the level of cellular PI(3)P however can be complex. Extraction of cellular ...