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Coauthors
Barbara Groth T Cell Biology Research Program, Centenary Institute of Cancer Medicine and Cell Biology, Australia
1 protocol

Holly A. Bolton
  • T Cell Biology Research Program, Centenary Institute of Cancer Medicine and Cell Biology, Australia
Contributions
  • 1 Author merit

Education

Ph.D. in Immunology, Faculty of Medicine, University of Sydney, 2013

Current position

Research Officer, Centenary Institute, The University of Sydney, Sydney, Australia

Publications

  1. Shklovskaya, E., Terry, A. M., Guy, T. V., Buckley, A., Bolton, H. A., Zhu, E., Holst, J. and Fazekas de St Groth, B. (2016). Tumour-specific CD4 T cells eradicate melanoma via indirect recognition of tumour-derived antigen. Immunol Cell Biol. (Epub ahead of print)
  2. Bolton, H. A., Zhu, E., Terry, A. M., Guy, T. V., Koh, W. P., Tan, S. Y., Power, C. A., Bertolino, P., Lahl, K., Sparwasser, T., Shklovskaya, E. and Fazekas de St Groth, B. (2015). Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease. J Clin Invest 125(9): 3627-3641.
  3. Bolton, H. A., Roediger, B. and Fazekas de St Groth, B. (2015). The effects of IL-2 and Treg cells on dendritic cell homeostasis are mediated indirectly via activation of conventional T cells. Eur J Immunol 45(4): 1141-1147.
  4. Roediger, B., Kyle, R., Tay, S. S., Mitchell, A. J., Bolton, H. A., Guy, T. V., Tan, S. Y., Forbes-Blom, E., Tong, P. L., Koller, Y., Shklovskaya, E., Iwashima, M., McCoy, K. D., Le Gros, G., Fazekas de St Groth, B. and Weninger, W. (2015). IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation. J Allergy Clin Immunol 136(6): 1653-1663 e1651-1657.
  5. Roediger, B., Kyle, R., Yip, K. H., Sumaria, N., Guy, T. V., Kim, B. S., Mitchell, A. J., Tay, S. S., Jain, R., Forbes-Blom, E., Chen, X., Tong, P. L., Bolton, H. A., Artis, D., Paul, W. E., Fazekas de St Groth, B., Grimbaldeston, M. A., Le Gros, G. and Weninger, W. (2013). Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol 14(6): 564-573.
1 Protocol published
Reconstitution of Lymphopaenic Mice with Regulatory and Conventional T cell Subsets
Authors:  Holly A. Bolton and Barbara Fazekas de St Groth, date: 05/20/2016, view: 1786, Q&A: 0
Transfer of mature T cells into immunodeficient mice results in sub-optimal reconstitution of the peripheral T cell pool. Under lymphopenic conditions, dendritic cells are released from tonic control by regulatory T cells (Tregs), and consequently ...