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Coauthors
Mitsuru Mizuno Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan
1 protocol

Takeshi Muneta Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, Japan
1 protocol

Nobutake Ozeki Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan
1 protocol

Ichiro Sekiya
  • Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan
Contributions
  • 1 Author merit

Education

Ph.D., School of Medicine, Tokyo Medical and Dental University, 2000

Current position

Director, Center for Stem Cell and Regenerative Medicine
Professor, Department of Applied Regenerative Medicine, Tokyo Medical and Dental University

Publications

  1. Kondo, S., Muneta, T., Nakagawa, Y., Koga, H., Watanabe, T., Tsuji, K., Sotome, S., Okawa, A., Kiuchi, S., Ono, H., Mizuno, M. and Sekiya, I. (2016). Transplantation of autologous synovial mesenchymal stem cells promotes meniscus regeneration in aged primates. J Orthop Res.
  2. Sekiya, I., Muneta, T., Horie, M. and Koga, H. (2015). Arthroscopic Transplantation of Synovial Stem Cells Improves Clinical Outcomes in Knees With Cartilage Defects. Clin Orthop Relat Res 473(7): 2316-2326.
  3. Nakagawa, Y., Muneta, T., Kondo, S., Mizuno, M., Takakuda, K., Ichinose, S., Tabuchi, T., Koga, H., Tsuji, K. and Sekiya, I. (2015). Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs. Osteoarthritis Cartilage 23(6): 1007-1017.
  4. Otabe, K., Nakahara, H., Hasegawa, A., Matsukawa, T., Ayabe, F., Onizuka, N., Inui, M., Takada, S., Ito, Y., Sekiya, I., Muneta, T., Lotz, M. and Asahara, H. (2015). Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. J Orthop Res 33(1): 1-8.
  5. Hatsushika, D., Muneta, T., Nakamura, T., Horie, M., Koga, H., Nakagawa, Y., Tsuji, K., Hishikawa, S., Kobayashi, E. and Sekiya, I. (2014). Repetitive allogeneic intraarticular injections of synovial mesenchymal stem cells promote meniscus regeneration in a porcine massive meniscus defect model. Osteoarthritis Cartilage 22(7): 941-950.
  6. Matsukura, Y., Muneta, T., Tsuji, K., Koga, H. and Sekiya, I. (2014). Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin Orthop Relat Res 472(5): 1357-1364.
  7. Nakamura, T., Sekiya, I., Muneta, T., Hatsushika, D., Horie, M., Tsuji, K., Kawarasaki, T., Watanabe, A., Hishikawa, S., Fujimoto, Y., Tanaka, H. and Kobayashi, E. (2012). Arthroscopic, histological and MRI analyses of cartilage repair after a minimally invasive method of transplantation of allogeneic synovial mesenchymal stromal cells into cartilage defects in pigs. Cytotherapy 14(3): 327-338.
  8. Sakaguchi, Y., Sekiya, I., Yagishita, K. and Muneta, T. (2005). Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 52(8): 2521-2529.
  9. Sekiya, I., Vuoristo, J. T., Larson, B. L. and Prockop, D. J. (2002). In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc Natl Acad Sci U S A 99(7): 4397-4402.

1 Protocol published
Preparation of Synovial Mesenchymal Stem Cells from a Rat Knee Joint
Authors:  Nobutake Ozeki, Takeshi Muneta, Mitsuru Mizuno and Ichiro Sekiya, date: 05/05/2016, view: 2076, Q&A: 0
Mesenchymal stem cells (MSCs), first described in human bone marrow, are emerging as promising cell-based therapeutics for a wide range of diseases (Caplan and Correa, 2011). MSCs have been isolated from various organs in the body, and synovial MSCs ...