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Coauthors
Sangeeta Bhaskar National Institute of Immunology, Aruna Asaf Ali Marg, India
2 protocols

Soumitra Marathe National Institute of Immunology, Aruna Asaf Ali Marg, India
1 protocol

Pawan Kumar
  • National Institute of Immunology, Aruna Asaf Ali Marg, India
Contributions
  • 2 Author merit

Education

Ph.D, University of Southampton, UK

Current Position

Research Instructor, University of Pittsburgh

Publications

  1. McAleer, J. P., Nguyen, N. L., Chen, K., Kumar, P., Ricks, D. M., Binnie, M., Armentrout, R. A., Pociask, D. A., Hein, A., Yu, A., Vikram, A., Bibby, K., Umesaki, Y., Rivera, A., Sheppard, D., Ouyang, W., Hooper, L. V. and Kolls, J. K. (2016). Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome. J Immunol 197(1): 97-107.
  2. Kumar, P., Monin, L., Castillo, P., Elsegeiny, W., Horne, W., Eddens, T., Vikram, A., Good, M., Schoenborn, A. A., Bibby, K., Montelaro, R. C., Metzger, D. W., Gulati, A. S. and Kolls, J. K. (2016). Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity 44(3): 659-671.
  3. Shih, V. F., Cox, J., Kljavin, N. M., Dengler, H. S., Reichelt, M., Kumar, P., Rangell, L., Kolls, J. K., Diehl, L., Ouyang, W. and Ghilardi, N. (2014). Homeostatic IL-23 receptor signaling limits Th17 response through IL-22-mediated containment of commensal microbiota. Proc Natl Acad Sci U S A 111(38): 13942-13947.
  4. Rajasekaran, K., Kumar, P., Schuldt, K. M., Peterson, E. J., Vanhaesebroeck, B., Dixit, V., Thakar, M. S. and Malarkannan, S. (2013). Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells. Nat Immunol 14(11): 1127-1136.
  5. Kumar, P., Thakar, M. S., Ouyang, W. and Malarkannan, S. (2013). IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection. Mucosal Immunol 6(1): 69-82.
  6. Kumar, P., Chen, K. and Kolls, J. K. (2013). Th17 cell based vaccines in mucosal immunity. Curr Opin Immunol 25(3): 373-380.
  7. Kumar, P. and Kolls, J. K. (2013). Act1-hsp90 heats up TH17 inflammation. Nat Immunol 14(1): 16-17.
  8. Kumar, P., Rajasekaran, K., Palmer, J. M., Thakar, M. S. and Malarkannan, S. (2013). IL-22: An Evolutionary Missing-Link Authenticating the Role of the Immune System in Tissue Regeneration. J Cancer 4(1): 57-65.
  9. Kumar, P., Bartoszek, A. E., Moran, T. M., Gorski, J., Bhattacharyya, S., Navidad, J. F., Thakar, M. S. and Malarkannan, S. (2012). High-throughput detection method for influenza virus. J Vis Exp(60).
  10. Malarkannan, S., Awasthi, A., Rajasekaran, K., Kumar, P., Schuldt, K. M., Bartoszek, A., Manoharan, N., Goldner, N. K., Umhoefer, C. M. and Thakar, M. S. (2012). IQGAP1: a regulator of intracellular spacetime relativity. J Immunol 188(5): 2057-2063.
  11. Rajasekaran, K., Chu, H., Kumar, P., Xiao, Y., Tinguely, M., Samarakoon, A., Kim, T. W., Li, X., Thakar, M. S., Zhang, J. and Malarkannan, S. (2011). Transforming growth factor-beta-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production. J Biol Chem 286(36): 31213-31224.
  12. Guo, H., Kumar, P. and Malarkannan, S. (2011). Evasion of natural killer cells by influenza virus. J Leukoc Biol 89(2): 189-194.
  13. Guo, H., Kumar, P., Moran, T. M., Garcia-Sastre, A., Zhou, Y. and Malarkannan, S. (2009). The functional impairment of natural killer cells during influenza virus infection. Immunol Cell Biol 87(8): 579-589.
  14. Majtan, J., Kumar, P., Majtan, T., Walls, A. F. and Klaudiny, J. (2010). Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes. Exp Dermatol 19(8): e73-79.
  15. Kumar, P., Williams, J. N., Durkin, K. L., Heckels, J. E., Friedmann, P. S., Healy, E. and Christodoulides, M. (2010). Neuropeptide alpha-MSH exerts pro-inflammatory effects on Neisseria meningitidis infection in vitro. Inflamm Res 59(2): 105-113.
  16. Pickard, C., Louafi, F., McGuire, C., Lowings, K., Kumar, P., Cooper, H., Dearman, R. J., Cumberbatch, M., Kimber, I., Healy, E. and Friedmann, P. S. (2009). The cutaneous biochemical redox barrier: a component of the innate immune defenses against sensitization by highly reactive environmental xenobiotics. J Immunol 183(11): 7576-7584.
  17. Majtan, J., Kumar, P., Koller, J., Dragunova, J. and Gabriz, J. (2009). Induction of metalloproteinase 9 secretion from human keratinocytes by pleuran (beta-glucan from Pleurotus ostreatus). Z Naturforsch C 64(7-8): 597-600.
2 Protocols published
Isolation of Genomic DNA from Mycobacterium Species
Authors:  Pawan Kumar, Soumitra Marathe and Sangeeta Bhaskar, date: 03/05/2016, view: 2853, Q&A: 1
Isolation of genomic DNA from Mycobacterium species has been a tedious procedure. This can primarily be attributed to thick and waxy cell wall of mycobacteria which hampers lysis of the bacterial cell. We have tested various approaches to ...
Analysis of T Cell Proliferating and Polarizing Potential of Murine Dendritic Cells in Allogeneic-mixed Leukocyte Reaction
Authors:  Pawan Kumar and Sangeeta Bhaskar, date: 03/05/2016, view: 2153, Q&A: 0
Dendritic cells (DCs) play a critical role in mounting the T cell response against different infectious agents. Nature and intensity of the induced T cell responses are defined by activation status of DCs. It is generally accepted that IL-12, ...