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Coauthors
Wei Cui Institute of Reproductive and Developmental Biology, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, UK
1 protocol
Coreviewers
Hui Zhu Department of Medicine, Stanford University, USA
16 protocols

Nicoletta Cordani Scientific Institute, Italy
10 protocols

Patrick Ovando-Roche
  • Post-Doc, Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School.
Research focus
  • Stem cell
  • Stem Cells. Retina. Brain. Ataxia.
Contributions
  • 1 Author merit
  • 2 Reviewer merit

Education

PhD, Imperial College London, 2014

Lab information

Vikram Khurana Lab.

Publications

1. Ovando-Roche, P., J. S. Yu, S. Testori, C. Ho and W. Cui (2014). "TRF2-Mediated Stabilization of hREST4 Is Critical for the Differentiation and Maintenance of Neural Progenitors." Stem Cells 32(8): 2111-2122. DOI: 10.1002/stem.1725

2. Ovando-Roche, P and W. Cui (2015). "Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination". Bio-protocol 5(13): e1525. DOI: 10.21769/BioProtoc.1525

3. Ovando-Roche, P., G. Annastasios, A. J. Smith, R. A. Pearson and Ali, R.R (2017). "Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration." Current Stem Cell Reports 3: 112. DOI:10.1007/s40778-017-0078-4.

1 Protocol published
Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination
Authors:  Wei Cui and Patrick Ovando-Roche, date: 07/05/2015, view: 3032, Q&A: 0
Ubiquitination is the first step of the ubiquitin-proteasome pathway that regulates cells for their homeostatic functions and is an enzymatic, protein post-translational modification process in which ubiquitin is transferred to a target protein ...
2 Protocols reviewed
Screening for Novel Endogenous Inflammatory Stimuli Using the Secreted Embryonic Alkaline Phosphatase NF-κB Reporter Assay
Authors:  Lorena Zuliani-Alvarez, Anna M. Piccinini and Kim S Midwood, date: 04/05/2017, view: 1301, Q&A: 0
An immune response can be activated by pathogenic stimuli, as well as endogenous danger signals, triggering the activation of pattern recognition receptors and initiating signalling cascades that lead to inflammation. This method uses THP1-BlueTM ...
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Retinal Differentiation of Mouse Embryonic Stem Cells
Author:  Anna La Torre, date: 07/05/2016, view: 2650, Q&A: 0
Groundbreaking studies from Dr. Yoshiki Sasai’s laboratory have recently introduced novel methods to differentiate mouse and human Embryonic Stem Cells (mESCs and hESCs) into organ-like 3D structures aimed to recapitulate developmental organogenesis ...
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