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Coauthors
Claudia Kemper MRC Centre for Transplantation, King's College, UK
1 protocol
Coreviewers
Alka Mehra Institute of Genomics and Integrative Biology
14 protocols

Cody Kime Center of Developmental Biology, RIKEN
1 protocol

Elizabeth Clarke Kaiser Permanente
5 protocols

Emmanuel Orta-Zavalza Universidad Autónoma de Ciudad Juárez
6 protocols

Reviewer
Martin V Kolev
  • Research associate, National Institutes of Health
Research focus
  • Immunology
  • T cells, intracellular complement, metabolism
  • 1 Author merit

Education

PhD, Cardiff University

Publications

Keeping It All Going-Complement Meets Metabolism. Kolev M, Kemper C.
Front Immunol. 2017 Jan 18;8:1. doi: 10.3389/fimmu.2017.00001. eCollection 2017. Review.

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.
Kolev M, Dimeloe S, Le Friec G, Navarini A, Arbore G, Povoleri GA, Fischer M, Belle R, Loeliger J, Develioglu L, Bantug GR, Watson J, Couzi L, Afzali B, Lavender P, Hess C, Kemper C.
Immunity. 2015 Jun 16;42(6):1033-47. doi: 10.1016/j.immuni.2015.05.024.
Complement--tapping into new sites and effector systems.
Kolev M, Le Friec G, Kemper C.
Nat Rev Immunol. 2014 Dec;14(12):811-20. doi: 10.1038/nri3761. Epub 2014 Nov 14. Review.
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C.
Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5.

1 Protocol published
Enzymatic Reactions and Detection of C3 Cleavage Fragments
Authors:  Claudia Kemper and Martin Kolev, date: 08/20/2014, view: 3834, Q&A: 0
The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions ...
9 Protocols reviewed
Semi-quantitative Analysis of H4K20me1 Levels in Living Cells Using Mintbody
Authors:  Yuko Sato and Hiroshi Kimura, date: 05/20/2017, view: 1378, Q&A: 0
Eukaryotic nuclear DNA wraps around histone proteins to form a nucleosome, a basic unit of chromatin. Posttranslational modification of histones plays an important role in gene regulation and chromosome duplication. Some modifications are quite ...
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Isolation of PBMCs Using Vacutainer® Cellular Preparation Tubes (CPTTM)
Authors:  Alaina Puleo, Chantia Carroll, Holden Maecker and Rohit Gupta, date: 01/20/2017, view: 4585, Q&A: 0
Peripheral blood mononuclear cell (PBMC) isolation is commonly done via density gradient centrifugation over Ficoll-Hypaque, a labor-intensive procedure that requires skilled technicians and can contribute to sample variability. Cellular Preparation ...
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