Nils Stein Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany
2 protocols

Manuela Knauft Department of Genebank, Leibniz-Institute of Plant Genetics and Crop Plant Research, Germany
1 protocol

Axel Himmelbach
  • Department of Genebank, Leibniz-Institute of Plant Genetics and Crop Plant Research, Germany
  • 1 Author merit


Ph.D. in Biochemistry, University of Basel, Switzerland, 1995

Current position

Postdoctoral fellow, Leibniz-Institute of Plant Genetics and Crop Plant Research, Department of Genebank, Corrensstr. 3, 06466 Gatersleben, Germany


  1. Yang, P., Lupken, T., Habekuss, A., Hensel, G., Steuernagel, B., Kilian, B., Ariyadasa, R., Himmelbach, A., Kumlehn, J., Scholz, U., Ordon, F. and Stein, N. (2014). PROTEIN DISULFIDE ISOMERASE LIKE 5-1 is a susceptibility factor to plant viruses. Proc Natl Acad Sci U S A 111(6): 2104-2109.
  2. Gawronski, P., Ariyadasa, R., Himmelbach, A., Poursarebani, N., Kilian, B., Stein, N., Steuernagel, B., Hensel, G., Kumlehn, J., Sehgal, S. K., Gill, B. S., Gould, P., Hall, A. and Schnurbusch, T. (2014). A distorted circadian clock causes early flowering and temperature-dependent variation in spike development in the Eps-3Am mutant of einkorn wheat. Genetics 196(4): 1253-1261.
  3. Pasquariello, M., Barabaschi, D., Himmelbach, A., Steuernagel, B., Ariyadasa, R., Stein, N., Gandolfi, F., Tenedini, E., Bernardis, I., Tagliafico, E., Pecchioni, N. and Francia, E. (2014). The barley Frost resistance-H2 locus. Funct Integr Genomics 14(1): 85-100.
  4. Ariyadasa, R., Mascher, M., Nussbaumer, T., Schulte, D., Frenkel, Z., Poursarebani, N., Zhou, R., Steuernagel, B., Gundlach, H., Taudien, S., Felder, M., Platzer, M., Himmelbach, A., Schmutzer, T., Hedley, P. E., Muehlbauer, G. J., Scholz, U., Korol, A., Mayer, K. F., Waugh, R., Langridge, P., Graner, A. and Stein, N. (2014). A sequence-ready physical map of barley anchored genetically by two million single-nucleotide polymorphisms. Plant Physiol 164(1): 412-423.
  5. Mascher, M., Muehlbauer, G. J., Rokhsar, D. S., Chapman, J., Schmutz, J., Barry, K., Munoz-Amatriain, M., Close, T. J., Wise, R. P., Schulman, A. H., Himmelbach, A., Mayer, K. F., Scholz, U., Poland, J. A., Stein, N. and Waugh, R. (2013). Anchoring and ordering NGS contig assemblies by population sequencing (POPSEQ). Plant J 76(4): 718-727.
  6. Mascher, M., Richmond, T. A., Gerhardt, D. J., Himmelbach, A., Clissold, L., Sampath, D., Ayling, S., Steuernagel, B., Pfeifer, M., D'Ascenzo, M., Akhunov, E. D., Hedley, P. E., Gonzales, A. M., Morrell, P. L., Kilian, B., Blattner, F. R., Scholz, U., Mayer, K. F., Flavell, A. J., Muehlbauer, G. J., Waugh, R., Jeddeloh, J. A. and Stein, N. (2013). Barley whole exome capture: a tool for genomic research in the genus Hordeum and beyond. Plant J 76(3): 494-505.
  7. Koppolu, R., Anwar, N., Sakuma, S., Tagiri, A., Lundqvist, U., Pourkheirandish, M., Rutten, T., Seiler, C., Himmelbach, A., Ariyadasa, R., Youssef, H. M., Stein, N., Sreenivasulu, N., Komatsuda, T. and Schnurbusch, T. (2013). Six-rowed spike4 (Vrs4) controls spikelet determinacy and row-type in barley. Proc Natl Acad Sci U S A 110(32): 13198-13203.
  8. Kapusi, E., Ma, L., Teo, C. H., Hensel, G., Himmelbach, A., Schubert, I., Mette, M. F., Kumlehn, J. and Houben, A. (2012). Telomere-mediated truncation of barley chromosomes. Chromosoma 121(2): 181-190.
  9. Mayer, K. F., Waugh, R., Brown, J. W., Schulman, A., Langridge, P., Platzer, M., Fincher, G. B., Muehlbauer, G. J., Sato, K., Close, T. J., Wise, R. P. and Stein, N. (2012). A physical, genetic and functional sequence assembly of the barley genome. Nature 491(7426): 711-716.
  10. Spies, A., Korzun, V., Bayles, R., Rajaraman, J., Himmelbach, A., Hedley, P. E. and Schweizer, P. (2011). Allele mining in barley genetic resources reveals genes of race-non-specific powdery mildew resistance. Front Plant Sci 2: 113.
  11. Douchkov, D., Johrde, A., Nowara, D., Himmelbach, A., Lueck, S., Niks, R. and Schweizer, P. (2011). Convergent evidence for a role of WIR1 proteins during the interaction of barley with the powdery mildew fungus Blumeria graminis. J Plant Physiol 168(1): 20-29.
  12. Hensel, G.*, Himmelbach, A.*, Chen, W., Douchkov, D. K. and Kumlehn, J. (2011). Transgene expression systems in the Triticeae cereals. J Plant Physiol 168(1): 30-44.
    *Common first authors
  13. Himmelbach, A., Liu, L., Zierold, U., Altschmied, L., Maucher, H., Beier, F., Muller, D., Hensel, G., Heise, A., Schutzendubel, A., Kumlehn, J. and Schweizer, P. (2010). Promoters of the barley germin-like GER4 gene cluster enable strong transgene expression in response to pathogen attack. Plant Cell 22(3): 937-952.
  14. Kocsy, G., Athmer, B., Perovic, D., Himmelbach, A., Szucs, A., Vashegyi, I., Schweizer, P., Galiba, G. and Stein, N. (2010). Regulation of gene expression by chromosome 5A during cold hardening in wheat. Mol Genet Genomics 283(4): 351-363.
  15. Zellerhoff, N.*, Himmelbach, A.*, Dong, W., Bieri, S., Schaffrath, U. and Schweizer, P. (2010). Nonhost resistance of barley to different fungal pathogens is associated with largely distinct, quantitative transcriptional responses. Plant Physiol 152(4): 2053-2066.
    *Common first authors
  16. Arend, M., Schnitzler, J. P., Ehlting, B., Hansch, R., Lange, T., Rennenberg, H., Himmelbach, A., Grill, E. and Fromm, J. (2009). Expression of the Arabidopsis mutant ABI1 gene alters abscisic acid sensitivity, stomatal development, and growth morphology in gray poplars. Plant Physiol 151(4): 2110-2119.
  17. Moes, D., Himmelbach, A., Korte, A., Haberer, G. and Grill, E. (2008). Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis. Plant J 54(5): 806-819.
  18. Himmelbach, A.*, Zierold, U.*, Hensel, G., Riechen, J., Douchkov, D., Schweizer, P. and Kumlehn, J. (2007). A set of modular binary vectors for transformation of cereals. Plant Physiol 145(4): 1192-1200.
    *Common first authors
  19. Lange, M., Himmelbach, A., Schweizer, P. and Scholz, U. (2007). Data Linkage Graph: computation, querying and knowledge discovery of life science database networks. Journal of Integrative Bioinformatics 4(3): e68.
  20. Hensel, G., Marthe, C., Kusserow, A., Himmelbach, A., Borisjuk, N., Goedeke, S., Kapusi, E., Otto, I., Kaydamov, C. and Broeders, S. (2007). Transgenic barley in applied research and biotechnology. Journal für Verbraucherschutz und Lebensmittelsicherheit 2: 104-104.
  21. Christmann, A., Moes, D., Himmelbach, A., Yang, Y., Tang, Y. and Grill, E. (2006). Integration of abscisic acid signalling into plant responses. Plant Biol (Stuttg) 8(3): 314-325.
  22. Zimmermann, G., Baumlein, H., Mock, H. P., Himmelbach, A. and Schweizer, P. (2006). The multigene family encoding germin-like proteins of barley. Regulation and function in Basal host resistance. Plant Physiol 142(1): 181-192.
  23. Yang, Y., Sulpice, R., Himmelbach, A., Meinhard, M., Christmann, A. and Grill, E. (2006). Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection. Proc Natl Acad Sci U S A 103(15): 6061-6066.
  24. Wu, Y., Sanchez, J. P., Lopez-Molina, L., Himmelbach, A., Grill, E. and Chua, N. H. (2003). The abi1-1 mutation blocks ABA signaling downstream of cADPR action. Plant J 34(3): 307-315.
  25. Himmelbach, A., Yang, Y. and Grill, E. (2003). Relay and control of abscisic acid signaling. Curr Opin Plant Biol 6(5): 470-479.
  26. Himmelbach, A., Hoffmann, T., Leube, M., Hohener, B. and Grill, E. (2002). Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis. EMBO J 21(12): 3029-3038.
  27. Park, H. S., Himmelbach, A., Browning, K. S., Hohn, T. and Ryabova, L. A. (2001). A plant viral "reinitiation" factor interacts with the host translational machinery. Cell 106(6): 723-733.
  28. Himmelbach, A., Benning, G., Hoffmann, T. and Grill, E. (2000). Targets of modifying plant growth and development by ABA-mediated signaling. In: Cherry et al. (eds). Plant Tolerance to Abiotic Stresses in Agriculture: Role of Genetic Engineering. NATO Science Series, 83, 223-232.
  29. Himmelbach, A., Iten, M. and Grill, E. (1998). Signalling of abscisic acid to regulate plant growth. Phil. Trans. R. Soc. Lond. B. Biol. Sci., 353, 1439-1444.
  30. Grill, E. and Himmelbach, A. (1998). ABA signal transduction. Curr Opin Plant Biol 1(5): 412-418.
  31. Himmelbach, A., Chapdelaine, Y. and Hohn, T. (1996). Interaction between cauliflower mosaic virus inclusion body protein and capsid protein: implications for viral assembly. Virology 217(1): 147-157.
  32. De Tapia, M., Himmelbach, A. and Hohn, T. (1993). Molecular dissection of the cauliflower mosaic virus translation transactivator. EMBO J 12(8): 3305-3314.
  33. Kondorosi, E., Györgypal, Z., Dusha, I., Baev, N., Pierre, M., Hoffmann, B., Himmelbach, A., Banfalvi, Z. and Kondorosi, A. (1990). Rhizobium meliloti nodulation genes and their regulation. In: Gresshoff, Roth, Stacey and Newton (eds). Nitrogen Fixation: Achievements and Objectives. Chapman and Hall, 207-213.
1 Protocol published
Plant Sequence Capture Optimised for Illumina Sequencing
Authors:  Axel Himmelbach, Manuela Knauft and Nils Stein, date: 07/05/2014, view: 5588, Q&A: 0
Plant Sequence Capture is used for targeted resequencing of whole exomes (all exons of a genome) of complex genomes e.g. barley and its relatives (Mascher et al., 2013). Sequencing and computing costs are significantly reduced ...